Development is a leading research journal in the field of developmental biology, covering topics ranging from stem cells and nuclear reprogramming to evolutionary developmental and systems biology, from neurobiology to regional specification, morphogenesis and organogenesis, and from epigenetics to the aetiology of disease.
Toots by Online Editor, Joyce Yu, Reviews Editor @amjeve & Executive Editor Katherine Brown
Oncogene overexpression accelerates heart regeneration
Read this Research Highlight showcasing work from Catherine Pfefferli, Anna Jaźwińska and colleagues from University of Fribourg:
Read the Stem Cells and Regeneration Article 'Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish' here:
Non-canonical imprinting in the spotlight
Read this Spotlight by Julien Richard Albert & Maxim Greenberg on non-canonical imprinting, what is known about the conservation of this phenomenon & how it impacts mammalian development:
Issue 11 is now complete!
On the cover: mouse blastocysts were cultured and trophoectoderm was differentiated to highly polyploid trophoblast giant cells. See Singh et al.: https://journals.biologists.com/dev/article/150/11/dev201581/316006/Myc-promotes-polyploidy-in-murine-trophoblast
Also in Issue 11:
▪ 4 Research Highlights on cell trajectories, EHT, Myc & Notch
▪ Author interview with Yuki Sato
▪ 2 Spotlights on hPSCs maturation & the challenges studying early human development
▪ Meeting review on quantitative modelling workshop
Maturing differentiated human pluripotent stem cells in vitro: methods and challenges
A Spotlight by Daniele Ottaviani, Milena Bellin, Christine Mummery & colleagues, discussing the challenges of hPSC maturation in vitro, using cardiomyocytes as an example.
Calculating cell differentiation trajectories
Read this Research Highlight showcasing work from
Simon Freedman, Bingxian Xu, Sidhartha Goyal & Madhav Mani:
Read the full #OpenAccess Research Article 'A dynamical systems treatment of transcriptomic trajectories in hematopoiesis' here:
Issue 10 is now complete!
On the cover: newly differentiated fat bodies (green) with lipid droplets (magenta) in the abdomen of a pharate adult fly. See Research article by Tsuyama et al: https://journals.biologists.com/dev/article/150/10/dev200815/310416/Dynamic-de-novo-adipose-tissue-development-during
Also in Issue 10:
▪5 Research Highlights on DH31, Hoxb, Shrub, EIF4A3 & morphogen gradients
▪Juan Modolell Obituary
▪Author interview with Zainab Afzal & Robb Krumlauf
▪Brain development & neurodegeneration Spotlight
▪Human embryo implantation Review
Human embryo implantation
Read this #OpenAccess Review from Joanne Muter, Vincent Lynch, Rajiv McCoy,
Jan Brosens from the University of Warwick, examining the foundational processes of pregnancy from an evolutionary perspective:
https://journals.biologists.com/dev/article/150/10/dev201507/310869/Human-embryo-implantation
I'm at #cshlsymp23! Happy to chat about @Dev_journal, @the_node and the @Co_Biologists charitable activities!
Of mice and men: a conserved role for EIF4A3 in neurogenesis
Read this Research Highlight showcasing work from Bianca Lupan, Rachel Solecki, Camila Musso, Fernando Alsina & Debra Silver from Duke University Medical Center:
https://journals.biologists.com/dev/article/150/10/e150_e1004/310766/Of-mice-and-men-a-conserved-role-for-EIF4A3-in
Read the Research Article 'The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis' here:
https://journals.biologists.com/dev/article/150/10/dev201619/310754/The-exon-junction-complex-component-EIF4A3-is
Smaller cells make more precise patterns
Read this Research Highlight showcasing work from Jan A. Adelmann, Roman Vetter, and
Dagmar Iber:
Read the full #OpenAcess Research Article 'The impact of cell size on morphogen gradient precision' here:
Shrub's double life in epithelial cell division
Read this Research Highlight showcasing work from Céline Bruelle, Roland Le Borgne and colleagues from Institut de Génétique et Développement de Rennes (IGDR):
Read the full Research Article here:
This paper planted tree number 1902, a silver birch (Betula pendula), in the Young People's Forest in Mead, UK.
Learn more about the
@For_Biologists:
https://forest.biologists.com/landscape/?id=85391
Regulation of anterior neurectoderm specification and differentiation by BMP signaling in ascidians
Read this Research Article by Agnès Roure, Rafath Chowdhury and Sébastien Darras:
CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation
Read this Research Article by Huiwen Zheng, Xiaobo Zhang, Jing Fu, Guohua Yuan and colleagues:
Mesodermal FGF and BMP govern the sequential stages of zebrafish thyroid specification
Read this #OpenAccess Research Article from Benoit Haerlingen, Sabine Costagliola and colleagues from the Institute of Interdisciplinary Research in Molecular Human Biology (IRIBHM), Université Libre de Bruxelles:
The brain on time: links between development and neurodegeneration
In this Spotlight,
Khadijeh Shabani and Bassem A. Hassan proposes that genetic forms of neurodegeneration might be rooted in neural development:
https://journals.biologists.com/dev/article/150/10/dev200397/310173/The-brain-on-time-links-between-development-and
RARE peek into Hoxb transcriptional regulation
New Research Highlight showcasing work from
Zainab Afzal, Robb Krumlauf and colleagues at Stowers Institute for Medical Research:
Read the #OpenAccess Research Article 'Shared retinoic acid responsive enhancers coordinately regulate nascent transcription of Hoxb coding and non-coding RNAs in the developing mouse neural tube':
And 'the people #behindthepaper' interview:
Our #MidWeekMovie shows adult-type fat body precursor cells as they begin to migrate dorsally from the #Drosophila abdomen, 30h APF. Taiichi Tsuyama, Tadashi Uemura and colleagues track the behaviour of AFBp cells during metamorphosis.
📖 @Dev_journal: https://journals.biologists.com/dev/article/150/10/dev200815/310416/Dynamic-de-novo-adipose-tissue-development-during
Our May Development presents... webinar will feature talks from
Anchel de Jaime Soguero, Elena Camacho Aguilar and Tyler Huycke
📅Wed 31 May 16:00BST (UTC +1)
Register to attend: https://us02web.zoom.us/webinar/register/9716740379156/WN_kp6mBFFVTES0AsoaG7ci1A
#DevPres #devbio #neurogenesis #BMP #WNT #patterning
Why not also register to attend our June webinar?
📅21 June 2023 – 16:00 BST. Chaired by James Briscoe
On the topic of growth and morphogenesis with Patricio Pérez-Henríquez, Stefania Tavano and Stefan Harmansa
https://us02web.zoom.us/webinar/register/9716740379156/WN_WP8-zPIaTbKeaXa0KmqjFQ
This #TechnicalTuesday we are highlighting tissue force microscopy (TiFM) from Chon Chan, Fengzhu Xiong, Arthur Michaut, Joana Vidigueira , Olivier Pourquié , L. Mahadevan. The authors use TiFM to measure forces in chick embryos with minimum invasiveness.
📖 @Dev_journal: https://journals.biologists.com/dev/article/150/9/dev201054/308160/Direct-force-measurement-and-loading-on-developing
Issue 9 is now complete!
On the cover: composite of microglia cells of the developing mouse embryo depicting the dynamic gradient between pro- and anti-inflammatory markers and amoeboid or branched morphology:
https://journals.biologists.com/dev/article/150/9/dev201574/307366/4931414P19Rik-a-microglia-chemoattractant-secreted
Also in Issue 9:
▪Research Highlights on senescence, ribosome biogenesis, cell rotation & tissue mechanics
▪Transitions in development with Bhavana Muralidharan
▪Development at a Glance on the PNS
▪#devbio #preprint highlights @preLights
https://journals.biologists.com/dev/issue/150/9
