Evolutionary and population genetics @UCDavis. Toots, grammar, & spelling are all my own fault. He/him.
#OA popgen book https://github.com/cooplab/popgen-notes/releases
3 years (and 2 kids) later, I finally revised the manuscript:
https://www.biorxiv.org/content/10.1101/2021.07.13.452277v2
we develop a #popgen method to locate genetic ancestors from tree sequences and apply it to arabidopsis thaliana.
software is ready to be applied to any dataset with Relate trees:
https://github.com/osmond-lab/spacetrees
check out our video to learn more: https://www.youtube.com/watch?v=4itER1uEKbQ
thanks for your patience @gcbias !
I've received sad and enraging news yesterday 🤬.
@EC_REA is taking away my MSCA postdoc fellowship.
The reason is an eligibility issue regarding mobility: they consider remote work in a 2021 pandemic world as counting towards the country I was residing in (which could have been anywhere in the world, but I happen to have French citizenship and was stuck there).
1/4
Now there are six cases of independently evolved distyly supergene that are hemizygous in thrums, in contrast to the classical genetic model for distyly.
Check out this cool new study on distylous Nymphoides indica in New Phytologist: https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.19264
#supergene #distyly #heterostyly #MatingSystem #FloweringPlants
The UC Davis Center for Population Biology postdoctoral fellowship is now being advertised. This is a great opportunity to come join our wonderful community of Evolution & Ecology here at Davis. Please RT.
My preprint with Andy Kern on a new genome-wide model of background selection (and statistical methods) applied to humans is now on BioRxiv! https://www.biorxiv.org/content/10.1101/2023.09.07.556762v1
Exhausted and dehydrated, I slowly walk the last few steps. “This has to be it,” I think to myself. Taking a deep breath, I close my eyes and turn the handle, whispering a little prayer as I step through. I open my eyes and the last trickle of hope leaks away. I am still in IKEA.
@connormorozumi
See Yaniv Brandvain's collection of egs in evolution & ecology
https://github.com/ybrandvain/GRFP
Even if you're ok with US law enforcement having access to such searches, these databases are just as easily usable by law enforcement, governments, & other interests outside the US to identify anonymous DNA samples often presumably w even fewer legal guardrails
The big picture here is that a small number of companies, some with serious COIs, have created a near US-wide searchable genetic database that they have effectively turned over to private contractors working for law enforcement.
Such a database would face controversy & legal hurdles if say the government tried to set one up themselves (see the legal debates over CODIS), yet the US has sleepwalked into allowing an even more dubious private system be setup apparently with few legal protections.
Ancestry and 23&me are not publicly searchable and so not usable by regular LE genetic genetic genealogy searches, but LE & genetic genealogists are finding some partial ways around this
On top of this the LE searchable sections of these genetic genealogy databases can be pretty shady. Both gedmatch and familytreeDNA are marketing themselves towards both LE and customers, which feels like a COI.
E.g. FamilytreeDNA forces customers to opt-out of being searchable by LE (except recent EU accounts) and so presumably FamilytreeDNA hoovered up a lot of inactive accounts into their database that now charge LE to access.
This potentially includes forensic genetic genealogists using entire databases
that according to DOJ guidelines are off limits to law enforcement searches. (Note that LE had previously hid their use of MyHeritage in GSK case https://latimes.com/california/story/2020-12-08/man-in-the-window)
The reason that they're violating this policy is likely bc genetic genealogy searches need large databases to find close cousins to an anonymous DNA sample, and databases opted-in for forensic searches are too small. See post by Doc Edge
https://gcbias.org/2018/05/07/how-lucky-was-the-genetic-investigation-in-the-golden-state-killer-case/
Genetic genealogists working with US law enforcement have routinely been searching genetic databases that were opted out of forensic searches violating DOJ guidelines (and covering their tracks). #GeneticGenealogy
https://theintercept.com/2023/08/18/gedmatch-dna-police-forensic-genetic-genealogy/
Flood risk from #Hilary in SE California deserts is genuinely alarming. Widespread
Heads up UC Riverside folks.
NWS Severe Weather Alert - prepare yourself and get any supplies you need now.
Aerial footage from the late night hours on Aug 8th clearly illustrates the wind-driven nature of the catastrophic #MauiFires. Note the elongated tendrils of fire burning in grass and brush moving rapidly in alignment with strong downslope winds.https://t.co/zxH0WyDr8G #Hawaii
I wont soon forget my first encounter with the wild-forget-me-not moth (eldorado national forest) #moths
Important article that sets the record straight on Rosalind Franklin's role in the discovery of DNA as a double helix -- with significant new findings.
#WomenInScience #DNA #DoubleHelix #HistoryofScience #RosalindFranklin
