Lmst

From Germany:

Transcriptome analysis of classical blood cells reveals down-regulation of proinflammatory genes in the classical monocytes of Long-COVID patients

https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1710783/abstract

Screenshot from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Transcriptome analysis of classical blood cells reveals down-regulation of proinflammatory genes in the classical monocytes of Long-COVID patients — Fricke et al.
"UMAP clustering of cells revealed distinct expression proﬁles between patients and controls in classical and intermediate, but not non-classical, monocytes. Differential gene expression analysis, based on a fold change threshold greater than 3 and a p-value threshold below 10−18, identified 40 DEGs in classical, 13 in intermediate, and 6 in non-classical monocytes, while other cell types showed minimal changes."

#COVIDISNOTOVER #WEARAMASK #DEMANDAFREECOVID19VACCINE

COVID-19 cases = 700+ last week, 800+ this week... but the Québec government DID NOT PROCURE *ENOUGH* #COVID19 vaccine to vaccinate ALL Québécois/ses. #SLOWCLAP #FAIL #polQC #QCpoli #assnat #BS #cdnpoli #polcan

Data on COVID-19 in Québec

Situation in Québec

The most recent data on the evolution of COVID-19, for the week of November 2 to 8, 2025, in Québec show:
« 805 new cases cases for a total of 1,540,919 cases

« 4 new deaths for a total of 21,531 deaths

👀 #CovidIsNotOver #COVIDisAirborne #N95sSaveLives #CleanAirNow #LongCovid #LongCovidKids #WeNotMe #TogetherWeCan #ShareTheCare https://bsky.app/profile/moriartylab.bsky.social/post/3m5cr2rpkh32g

Ayé, je viens de faire mon vaccin anti COVID. C'était gratuit et sans rendez-vous en pharmacie. Mesurons notre privilège de disposer d'un système de santé qui fonctionne encore avant qu'on nous en prive !
#CovidIsNotOver #vaccination

Photomontage d'un chat portant dans une patte, un flacon où est écrit le mot vaccine et une seringue dans l'autre patte.

Hat es schon jemand angesehen/angehört?

Enquete-Kommission Corona
Heute (10.11.): „Schutz vulnerabler Bevölkerungsgruppen und Umgang mit Langzeitfolgen (Long-Covid/Post-Vac)“

https://www.bundestag.de/ausschuesse/weitere_gremien/ee01/anhoerungen/1118986-1118986

#COVID #COVID19 #LongCOVID #CovidIsNotOver #EnqueteKommission #Corona

I don't know if this show that Julia Doubleday is writing about will convey the feelings of still being in a group of people continuing to protect ourselves from Covid, as well as Julia Doubleday expresses it herself here. This is a great read for those of us Covid-Aware/Cautious.

"They said back to normal, and they meant back to normal. All of it. Capitalism, racism, sexism, environmental destruction, and disease. Back to the office. Welcome back, back to the Hive Mind. Hustle for your check. Buy yourself something nice. Immigrants are the problem. Disabled people are the problem. Trans people are the problem. Woke is dead. Now take that fucking mask off your face."

https://www.thegauntlet.news/p/pluribus-captures-the-isolation-of

#Covid #CovidIsNotOver #LongCOVID #WearAMask

Wer die dreistündige Anhörung zum Schutz vulnerabler Bevölkerungsgruppen der Enquete-Kommission des Bundestages heute wie ich nicht live verfolgen konnte, findet hier die Aufzeichnung:
https://www.bundestag.de/mediathek/video?videoid=7643805

#MECFS #LongCovid #PostCovid #PostVac #Corona #Pandemie #Enquete #Bundestag #CovidIsNotOver

💔 #ItDidntHaveToBeThisWay #Measles #CovidIsNotOver #COVIDisAirborne #N95sSaveLives #CleanAirNow #LongCovid #LongCovidKids #WeNotMe #TogetherWeCan #ShareTheCare
https://www.statnews.com/2025/11/10/measles-canada-americas-paho-who-elimination-status/

We are entering The Holiday Season, which for me is now The Dreaded Season of Managing Obligations and Being That Person "Navigating" Covid Risks at Indoor Gatherings.

I quite dislike it.

By now most people have stopped inviting me, but there are still the family obligations that are the most difficult to not attend.

#CovidIsNotOver

⬆️ Impfmöglichkeit Booster Auffrischung 💉 #Novavax #Nuvaxovid #JN.1 📍 #Aachen #NRW 📆 mit Termin (📞); Termine ab 29.11.25 📞 0241-91993694 🚦Ü12. Stikotreue unklar, gern berichten. @drmccoy.info @safeairdocs.bsky.social @bildungabersicher.net #COVID19 #CovidIsNotOver #TeamVorsicht #Impfung #nuvax25

In 2020 somebody scrawled "PCR-Test = Idiotentest" onto this wall. They had added other anti-measure sentiments on the footpath but in chalk, so those are no longer there.
Because this uninformed and incurious attitude has become more prevalent, I #MaskUp
#CovidIsNotOver #MaskUpMonday #SaltingTheVibes

a white woman stands in front of a wall full of graffiti and tags. She is wearing a grey and blue toque, a dark blue coat and a blue respirator.

#CovidIsNotOver #CovidIsAirborne #KeepMasksInHealthCare #maskup #WearAMask #VaccinesPlus #covid19 #covid #SARSCov2 #DavosSafe #BringBackMasks #CovidConscious #CleanAir #CovidCautious

A colorful illustration showing two smiling characters, one with a stethoscope, washing their hands at a sink. A speech bubble emphasizes the importance of washing hands to prevent airborne viruses. The background is bright orange, enhancing the cheerful tone.

Raj's dashboard, updated today, shows Stratus wildly diversified, having spawned multiple third-generation pango aliases & descendant recombinants (incl much of Other on this chart). Previous data had suggested XFG was stagnant.

GISAID data for the latter two-weeks-and-change of the most recent period is dominated by submissions from California (120 sequences), followed by New York (87), Minnesota (49), and Colorado (36)—paltry all round.

Despite profound diversification of XFG, CDC had yet to break out estimates for any of its subvariants.

#CDC's most recent dataset, updated Sept 26, showed Stratus XFG family dominating, with Nimbus NB.1.8.1 / PQ in second place, down to one-fourteenth share, this nearly neck-in-neck with FDA Vaccine Target LP.8.1 at one-seventeenth share.

Note that, in absence of robust data from states, CDC has given up modeling historical estimates, instead giving only shares of reported sequences.

❖ #ThisIsOurPolio #variants #CovidIsNotOver #dataviz #datavis

Chart: Est. & Reported U.S. Variant Proportions by Common Name
Sources: CDC, Cov-Lineages, NYITCOM, others

[ beadsland on Ko-fi ]

Reskin of CDC's Variants Nowcast, and any significant variants in GISAID not broken out by CDC.

Four bar-style tree-charts, for four-week periods through 9/28–10/25. Legend of last four-week period, organized by subheadings of color-grouped families and convergent clusters. Percentages overlay each color key, reflecting share as of most recent tree-chart.

Stratus XFG family accounts for over three quarters share.

For 9/28–10/25, leading GISAID sequences make up for outdated CDC Nowcast. Packed bubble charts fill single-variant tiles.

Legend:

LF.7 + NTD-meets-RBD [red]:
77% - XFG.2†, XFG.3†, XFG.14.1†, XFG.3.4.1 / QF†, XFG.5.1†, XFG.4.1†, XFG.5.2†, XFG.3.4.3 / QS† & other Stratus XFG

JN.1.11 [browns]:
2% - FDA-Vaccine-Target LP.8.1
1% - KP.3
½% - other JN.1.11

LF.7 + NTD-meets-RBD [purples]:
½% - XFC
¾% - other LF.7 + NTD-meets-RBD

JN.1 + FLiRT-LF-7 [blues]:
0% - LF.7.9
1% - other LF.7

JN.1 [greens]:
0% - JN.1.16.1 / LF
0% - other WHO-Vaccine-Target JN.1

Other [greys]:
8% - Nimbus NB.1.8.1 / PQ
10% - Other (not tallied)
_____

Stratus XFG is a child of April's WHO-Vaccine-Target scion LF.7 and Juneish JN.1.11 scion LP.8.1.2 / NW.

XFC is a child of April's WHO-Vaccine-Target scion LF.7 and Mayish JN.1.11 scion LP.8.1.1 / NY.

† Variants, not broken out by CDC, that represent significant share of recent GISAID sequences.

All of this is to say is that those of you who understand that #CovidIsNotOver would likely seriously relate to #Pluribus. I will note however that you may need to take breaks while watching, because the subject matter is heavy.

🚦Ü18. STIKO-Strenge unklar, gern berichten. Infos: www.radiocottbus.de/lausitz-news... Kontaktformular: www.osl-online.de/impfsprechst... #COVID19 #CovidIsNotOver #TeamVorsicht #Impfung #impflp81

Impfmöglichkeit Booster Auffrischung 💉Grippe #Biontech #Comirnaty #L.P.8.1 📆Di13-17, Do13-16:30 Uhr m. Termin (📞, 📧, Kontaktformular) 🏥Gesundheitsamt 📍Großenhainer Str. 62 01968 #Senftenberg #Brandenburg 📞03573-8704342 📧 Hygiene@osl-online.de #COVID19 #CovidIsNotOver #TeamVorsicht #Impfung #impflp81

:idle3: «Si ves a alguien con mascarilla y tu reacción es "¿por qué siguen haciéndolo?" — Es porque ellos siguen las recomendaciones científicas, y tú no.

:idle3: Ustedes siguen una norma social creada por la privatización de la salud pública, y ellos no.

:idle3: ¡No hay necesidad de seguir preguntándose!»
https://x.com/loscharlos/status/1983640215999930820?s=46&t=qEya17FQSjp9bz3bzc2DGg
———
#COVID19 no es estacional, si no usas mascarilla en espacios cerrados, se da al #SARSCoV2 oportunidad para mutar y dañar salud y vida. #CovidIsNotOver

Medscape: "Canadian Cardiologists Must Step Up Care for Long COVID"

https://www.medscape.com/viewarticle/canadian-cardiologists-must-step-care-long-covid-2025a1000u2r

Report on an educational session from the Canadian Cardiovascular Congress (CCC) 2025 about cardiovascular issues associated with #LongCovid .

Hashtags:

@longcovid
#PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19@fedigroups.social #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #auscovid19

⬆️ Impfmöglichkeit Booster Auffrischung 💉Grippe #Biontech #Comirnaty #L.P.8.1 📍 #Rendsburg #SH 📆 Mo-Do 10:30-11:30 & Di 16-17:30 ohne Termin 🚦Mindestalter/STIKO-Strenge unklar; Praxisfremde: Formular mitbringen Info: hausarztpraxis-kronwerk.de #COVID19 #CovidIsNotOver #TeamVorsicht #Impfung #impflp81

Hausarztpraxis Kronwerk in Ren...

#COVIDisNotOver

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