The mRNA Dialectic: Building a Realistic Bridge Between Hope and Exploitation @SSRN https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5292547
#mRNATechnology #TechnologicalDialectic #Biopolitics #PlatformCapitalism #PrimitiveAccumulationOfTheBody #PostColonialTheory #GlobalHealthInequality #PatentRegimes #Blockchain #CRISPR #OpenSourceBiotechnology #CheapNature
#Crispr
De discussie over gevaren van #CRISPR-Cas is verstomd, maar de vraag wie er geld mee gaat verdienen leeft nog volop. Microbioloog John van der Oost zet zich in om genredigeren ten goede te laten komen van mens, maatschappij en milieu. https://www.resource-online.nl/index.php/2025/06/11/het-finetunen-van-crispr-cas-is-begonnen/
Genetic Engineering Will Change Everything Forever – CRISPR
A heartening story about how CRISPR is being used to develop citrus trees resistant to huanglongbing (HLB, also known as citrus greening), carried by the the Asian citrus psyllid.
In 20 years, the disease reduced citrus production in Florida by more than 60%: infected trees can die in as few as 5 years.
If all goes well, in 2027 resistant trees may be planted in commercial orchards.
#CitrusProduction #Florida #Oranges #BacterialDisease #InsectVector #CRISPR
Impressive work on functional screening in human cells:
https://pubmed.ncbi.nlm.nih.gov/40442371/
With one of the most detailed data analysis and visualization code available:
https://github.com/rasilab/nugent_2024
PS The use of barcoded RNA reminded me our own past work in yeast (https://pubmed.ncbi.nlm.nih.gov/24529707/)
Krypto-Milliardär Brian Armstrong ist bereit, in CRISPR-Baby-Technologie zu investieren. Es die erste große kommerzielle Investition in eines der umstrittensten Projekte der Medizin.
https://t3n.de/news/designer-babys-durch-crispr-coinbase-ceo-will-in-gentechnik-investieren-1691659/
Công nghệ chỉnh sửa gen mới phát triển bởi các nhà khoa học Israel và Trung Quốc hứa hẹn sẽ cách mạng hóa nông nghiệp. Phương pháp này vượt qua hạn chế của CRISPR, cho phép chỉnh sửa hàng ngàn gen một lúc, mở ra cơ hội cho giống cây chất lượng cao hơn. #ChinhSuaGen #NongNghiep #CongNghe #CRISPR https://ift.tt/JBCN3LZ
This isn’t science fiction. A CRISPR-edited cell therapy is curing aggressive cancers with off-the-shelf convenience. #Immunotherapy #CRISPR #CAR-T
https://geekoo.news/off-the-shelf-immunotherapy-turns-the-tide-against-rare-t-cell-cancers/
Gentechnik-Debatte: Landwirte kämpfen mit Klimaschäden auf Feldern | heise online https://www.heise.de/news/Gentechnik-Debatte-Landwirte-kaempfen-mit-Klimaschaeden-auf-Feldern-10435354.html #CRISPR #DNA #Forschung #research #Wissenschaft #science
December 2023
"Researchers are closing in on ways to produce CAR T cells in the body, raising hopes that the notoriously expensive and bespoke cancer therapies might one day become more accessible.
In CAR-T treatment, immune cells called T cells are removed from the person receiving treatment, engineered to target cancer cells and reintroduced to their body. The process has yielded dramatic recoveries from advanced forms of some blood cancers, but its high price and technical difficulty have placed it out of reach for many people.
Results presented at the American Society of Hematology annual meeting in San Diego, California on 11 December suggest that people undergoing treatment might eventually just get an injection of a virus that infects T cells. The virus would then insert the genes needed to guide the T cells to tumour cells."
June 2025:
"Some biotechnology companies have an answer: alter T cells inside the body instead. Treatments that deliver a gene for the CAR protein to cells in the blood could be mass produced and available on demand — theoretically, at a much lower price than current CAR-T therapies. A single dose of commercial CAR-T therapy costs around $500,000. A vial of in vivo treatment might cost an order of magnitude less.
The idea has some high-profile proponents. The founders of Capstan Therapeutics, a company in San Diego, California, that is focused exclusively on in vivo cell therapies, include CAR-T pioneers Levine and Carl June, as well as Drew Weissman, who won a Nobel prize for his work on messenger RNA vaccines. CRISPR–Cas9 pioneer and Nobel prizewinner Jennifer Doudna has co-founded a separate company, Azalea Therapeutics in Berkeley, California, that is developing in vivo CAR T. And big pharma is taking notice. In March, the biopharmaceutical firm AstraZeneca agreed to pay up to $1 billion for the Belgium-based in vivo CAR-T company EsoBiotec, which launched its first human trial of an in vivo CAR-T therapy in January."
Gentechnik-Debatte: Landwirte kämpfen mit Klimaschäden auf Feldern
Angesichts der Klimakrise wächst bei einigen Landwirten die Hoffnung auf gentechnisch veränderte Pflanzen – doch Kritiker warnen vor
Risiken.
#CRISPR #Genetik #Gentechnik #Landwirtschaft #Wissenschaft #news
"A selected encyclopedia of major gene-editing systems, together with illustrated diagrams."
Just mind bogglingly amazing - modern #GeneEditing therapies! Doesn't get more #PrecisionMedicine than this!
"First Personalized CRISPR Gene Editing Therapy Patient Baby KJ Discharged
Three hundred and seven days after he was first admitted to Children’s Hospital of Philadelphia (CHOP), the 10-month-old went home after being treated with a bespoke base editing approach"
#Science #CRISPR #genetics
https://www.insideprecisionmedicine.com/topics/precision-medicine/first-personalized-crispr-gene-editing-therapy-patient-baby-kj-discharged/
A Gene Editing Strategy to Repair Huntington's Defects
"A lot more studies would be needed before we can know if disrupting these repeats with a base editor could be a viable therapeutic strategy to treat patients. But being able to illuminate the biological consequences of interrupted repeats is a really useful and important milestone," explained senior study author Dr David Liu.
#CRISPR #genetics #research #biology #biotechnology #science #Huntingtons
#Time: yes, it’s a #Dimension, but no, it’s not like #Space : Medium
'#DarkPhoton' theory of #Light aims to tear up a century of #Physics : New Sci
World’s first #Personalized #CRISPR #Therapy given to baby with #Genetic #Disease : Nature
Check our latest #KnowledgeLinks
"The first in-human trial of a #CRISPR Cas system delivered by adeno-associated virus 9 gene therapy to treat #HIV was able to target only the intended DNA and cleared the blood within 6 months."
https://www.eatg.org/hiv-news/first-in-human-trial-of-crispr-gene-therapy-for-hiv/
I'd like to read more about DNA & CRISPR. The origins, the background story, but also how CRISPR works etc.
Does anybody know which book I should read? There are multiple books on the topic & it's hard for a layman to choose from.
My background is in IT & (Interaction) Design.
Y por acabar con una noticia positiva, un hito en medicina:
Doudna, a next-gen supercomputer launching in 2026, combines Nvidia’s Vera Rubin chips and Dell’s liquid-cooled servers to supercharge scientific research across AI, biology, climate, and national security. Named after CRISPR pioneer Jennifer Doudna, it marks a major leap in high-performance computing and U.S. tech leadership.
#Doudna #Supercomputing #AI #HPC #Nvidia #Dell #CRISPR #ScienceRevolution #TechLeadership #DOE
Read Full Article Here :- https://www.techi.com/doudna-supercomputer-nvidia-dell-ai-hpc/
Client Info
Server: https://mastodon.social
Version: 2025.04
Repository: https://github.com/cyevgeniy/lmst