Bei einigen neurologischen Entwicklungsstörungen besteht häufig eine Mutation im Gen RNU4-2, zeigen Forschende in Nature Medicine. Neue Erkenntnis dank Erforschung des #DarkGenome. Experten sehen wichtigen Schritt für die Diagnostik: https://www.sciencemediacenter.de/alle-angebote/research-in-context/details/news/mutationen-im-rnu4-2-gen-loesen-entwicklungsstoerungen-aus?mtm_campaign=mastodon&mtm_kwd=mutation-gen-entwicklungsstoerungen

Scientists Reveal Structure of Ancient Virus-Like Genetic Element
https://www.sci.news/genetics/line-1-retrotransposon-12539.html
#Genetics #Genome #Parasites #DarkGenome #LINEー1 #retrotransposons #JumpingGenes

Dark Genome Discovery: Researchers Reveal “Ancient Genetic Parasite” Implicated in Human Diseases
https://scitechdaily.com/dark-genome-discovery-researchers-reveal-ancient-genetic-parasite-implicated-in-human-diseases/
#Genetics #Genome #Parasites #DarkGenome #LINEー1 #retrotransposons #JumpingGenes

Clearly, there is still much to learn about this corner of the dark genome defined by HEATR5 proteins and their co-factors.

#Biorxiv #Preprint #MembraneTraffic #DarkGenome #DarkProteome #RareDisease #AlphaFold #AlphaFold2 #ProteinPrediction #Golgi #Clathrin #CellBiology #biochemistry #Bioscience

@bbruneau We are glad you are here Benoit- #DevBiol #Heart #Chromatin #DarkGenome