Could a fungus from ancient tombs help cure cancer? Meet the Penn team turning deadly spores into the next breakthrough drug. #FungalMedicine #CancerResearch #DrugDiscovery

https://geekoo.news/from-deadly-fungus-to-cancer-fighter-scientists-transform-natures-toxin-into-a-new-drug/

#AI #Genomics #DeepMind #AlphaGenome #Biotech #DrugDiscovery #PrecisionMedicine #ArtificialIntelligence #FutureOfHealth #SyntheticBiology #LifeSciences #HealthTech #MachineLearning #Google

🚀 Mavatar, the Swedish #HealthTech innovator, is launching in the U.S. with a game-changing AI platform for #PrecisionMedicine. Mavatar Discovery helps simulate disease progression, discover biomarkers, and repurpose drugs using transcriptomic data and machine learning.
Read our exclusive interview with Mavatar CEO Johan Juhlin.
👉 https://www.movetheneedle.news/start-ups/using-ai-to-revolutionize-precision-medicine/
#AI #DigitalTwins #DrugDiscovery #RareDiseases #Biotech #OpenScience #Mavatar #HealthcareInnovation

We have an exciting program of talks for you for the @LED3hub Lectures 2025/2026!

If you are interested, already mark your calendars and come by to learn about various aspects of early drug discovery. https://www.universiteitleiden.nl/en/science/led3/led3-lectures

#DrugDiscovery #ChemSky #Chemistry #ChemBio

We have an exciting program of talks for you for the @led3hub.bsky.social Lectures 2025/2026! If you are interested, already mark your calendars and come by to learn about various aspects of early drug discovery. www.universiteitleiden.nl/en/science/l... #DrugDiscovery #ChemSky #Chemistry #ChemBio

RE: https://bsky.app/profile/did:plc:jnlt3o3km3ebst2vcigkwdch/post/3lse3k54hnc27

Are you an academic researcher running #MolecularDocking?

Leverage #BOINC Central to access free, large-scale distributed computing for your #AutoDock #Vina jobs.
Our guide walks you through setup to submission:
https://github.com/BOINC/boinc-autodock-vina/wiki

#Autodock:
https://youtu.be/NJ8sxnipMUs

#Vina:
https://youtu.be/ypBh-Sw_jTg

#Vinardo:
https://youtu.be/dGiZbEje-Ok

#Vina and #Raccoon2:
https://youtu.be/g7jago5-TvU

#DrugDiscovery #VirtualScreening #HPC

The final #FlashTalk session gave another exciting overview of different early #DrugDiscovery topics including #CovalentInhibitors for glycosidases (Rob Lammers), host-directed therapies for bacterial infections (Bart van Lieshout) and covalently drugging transcription factors (Shaima Abdalla).

The second #FlashTalk session at #LED3Symposium was another firework of diverse early #DrugDiscovery topics including β-lactamase evolution (Cristina López Gallego), EC50 determinations (Chenyu Wang), transcription factor inhibitors (Brecht Ellenbroek) and natural products discovery (Pavlo Hrab).

Call for papers

Disease Models & Mechanisms (DMM) invites you to submit your latest research to their upcoming special issue: In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery.

Find out more: https://journals.biologists.com/dmm/pages/in-vitro-models

#InVitro #DrugDiscovery #Research #CallForPapers #Disease #Humans #HumanDisease #Science #Communication #Experiment

We used NGN2-reprogrammed iPSC neurons with glutamatergic hyperactivity and tested phenytoin, perampanel, and carbamazepine.

Read the full paper here 👇
📄 Communications Biology
🔗 http://dx.doi.org/10.1038/s42003-025-08194-6

#Neurotech #SBI #DrugDiscovery #Epilepsy #Organoids #BrainOnAChip #stemcells #bioinformatics #invitromodeling

On Tuesday the UK government announced OpenBind. It looks really exciting for generating a ton of molecule-protein datasets. I think it's going to be important, if it goes well.

https://r.dallaway.com/posts/openbind-cannot-come-soon-enough

#ai #drugDiscovery

Despite a century of use in #DrugDiscovery, specialized metabolism continues to amaze. Justin Nodwell explores a @PLOSBiology study that uses a novel computational approach to uncover unsuspected functions of a compound produced by #Streptomyces. Paper: https://plos.io/43UVUPB Primer: https://plos.io/4n25bOF

https://www.alojapan.com/1296892/japans-oldest-pharma-firm-to-be-sold-to-bain-capital/ Japan’s Oldest Pharma Firm to Be Sold to Bain Capital #acquisition #BainCapital #DrugDiscovery #Economy&Tech #Japan #JapanNews #JapanTopics #JapaneseCompanies #MitsubishiChemical #MitsubishiTanabePharma #news #PharmaCompany #Pharmaceutical #PharmaceuticalCompany #PharmaceuticalIndustry #PrivateEquity Mitsubishi Tanabe Pharma, Japan’s oldest pharmaceutical company with a 350-year history, is approaching a major turning point. Its par…

🌿 Natural products hold the key to life-saving medicines, but their complexity has always been a barrier. Exciting news: enzymatic and genetic breakthroughs are now making their synthesis easier! What could this mean for future drug development? #NaturalProducts #DrugDiscovery #Innovation 🧬💡 https://phys.org/news/2025-05-enzymatic-genetic-advances-synthesis-natural.html

AI: Cure All Diseases - Eric Schmidt on AI

#computation #drugdiscovery #drugs #ai #modeling

🧬 New review out in Drug Discovery Today:

🔗 https://doi.org/10.1016/j.drudis.2025.104382

We take a critical look at how AI — especially AlphaFold(-Multimer/3) — has changed protein complex prediction.

End-to-end models work well for rigid complexes. Flexibility, disorder, and transient interfaces remain unsolved.

AI is shiny. Biology is complicated. We map what’s working, what isn’t, and what’s next.

#ComputationalBiology #Bioinformatics #DrugDiscovery #AlphaFold

CD BioSciences launches customizable aging mouse models, revolutionizing preclinical drug research with advanced gene-editing and comprehensive research support. Accelerating discoveries in age-related disease treatments. #AgingResearch #DrugDiscovery

Excited to be at VU Amsterdam to listen to the Nauta Lecture of György Keserű on "Covalent fragment approaches in drug discovery". He gave a great overview of his group`s many groundbreaking contributions to tool development for #DrugDiscovery and his newest work on photoactivatable fragments.(1/7)

He started by giving a very clear overview of the concept of #CovalentInhibitors and the important advantages that they can have in #DrugDiscovery. He especially highlighted, how powerful covalent fragments can be in this context. (2/7) www.sciencedirect.com/science/arti...

Covalent fragment approaches t...

He started by giving a very clear overview of the concept of #CovalentInhibitors and the important advantages that they can have in #DrugDiscovery. He especially highlighted, how powerful covalent fragments can be in this context. (2/7) https://www.sciencedirect.com/science/article/pii/S0165614723001840?via%3Dihub