#Filoviruses

Giuseppe MichieliGMIK69@mstdn.science
2024-07-23

Non #Ebola #Filoviruses: Potential #Threats to Global #Health #Security mdpi.com/1999-4915/16/8/1179

In this #review, we summarize current #knowledge on non-Ebola filoviruses (#Bombali virus, #Bundibugyo virus, #Reston virus, #Sudan virus, #TaiForest virus, #Marburg virus, #Ravn virus, #Lloviu virus, ... and Dehong virus) and suggest some strategies to accelerate specific #countermeasure development.

2023-01-31

Inmazeb is an FDA-approved antibody therapeutic for #Ebola virus. Now we know exactly HOW this powerful antibody cocktail neutralizes the virus.

Thank you @cellpress for featuring this fascinating #StructuralBiology work from LJI's Saphire Lab, Boston University researchers, and Regeneron: sciencedirect.com/science/arti

#Immunology #Virology #DrugDevelopment #CryoEM #Filoviruses #EbolaVirus #InfectiousDisease #antibodies

Structural figure from the Cell Host & Microbe paper. Shows the Ebola virus glycoprotein in gray. We see how the three antibodies in Inmazeb target sites on the glycoprotein. Antibody REGN3 (dark blue) targets the receptor binding site. Antibody REGN3470 (light blue) targets the glycan cap. Antibody REGN3479 targets the fusion loop. Structure shown at 3.1 angstrom resolution.
myownpetard blue checkmarkmyownpetard
2022-11-27

i really hope ebola doesn't spread any further. i wish it wouldn't have spread to any human at all! that is some fcked up shit.

2022-11-12

#Introduction toot.

I'm a molecular virologist studying #BSL4 pathogens, primarily #filoviruses like #Ebola #Lloviu and #Marburg viruses at the #NEIDL at #BostonUniversity
I'm a big proponent of collaborating and #OpenScience

I love exploring the outdoors; #camping #hiking #kayaking #snowshoeing
I also enjoy #gardening and #brewing beer and cider.
I'm a huge #nerd at home too: my non-science reading list is mostly #nature #sciencefiction and #fantasy and I play #dungeonsanddragons

#nomoa

2022-11-06

#introduction
Hi all. I'm just starting to explore mastadon. I'm a #diseaseecologist who studies #zoonotic #viruses in wildlife and how they #spillover into livestock and people. I work for a science-based nonprofit called EcoHealth Alliance. My research focuses on #bats and their associated #henipaviruses, #coronaviruses and #filoviruses in Asia and Africa.

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