Finally, my warmest thanks to the CRICS-TriggerSep Scientific Board for their crucial role in designing and conducting this trial.
https://www.nejm.org/doi/full/10.1056/NEJMoa2502136
#EVERDAC #CriticalCare #ESICM2025 #NEJM #ICU #Research #CRICSTriggerSep
Apixaban for Extended Treatment of Provoked Venous Thromboembolism. #NEJM "Low-intensity therapy with apixaban for 12 months resulted in a lower risk of symptomatic recurrent VTE than placebo, with a low risk of major bleeding." www.nejm.org/doi/full/10....
Medical Imaging and Pediatric and Adolescent Hematologic Cancer Risk. #nejm
"Our study suggests an association between exposure to radiation from medical imaging and a small but significantly increased risk of hematologic cancer among children and adolescents."
www.nejm.org/doi/full/10....
Medical Imaging and Pediatric ...
In adults with obesity, 72-week treatment with orforglipron led to significantly greater reductions in body weight than placebo; the adverse-event profile was consistent with that of other GLP-1 receptor agonists. #NEJM
www.nejm.org/doi/full/10....
Orforglipron, an Oral Small-Mo...
Marburg Virus Disease in Rwanda, 2024 — Public Health and Clinical Responses. #NEJM Open Access www.nejm.org/doi/full/10....
In resectable lung cancer, neoadjuvant nivolumab plus chemotherapy improved 5-year overall survival, with no lung cancer deaths reported at 5 years in patients with a pathological complete response. #NEJM www.nejm.org/doi/full/10....
@hugoestr los habituales que me faltan de esta semana para estar al día:
#EnGuàrdia
#MacBreakWeekly
#WeirdestThing
#NEJM this week
#LateShow with #StephenColbert
#LeyendasLegendarias
#StarTrek’s #MissionLog
#BeyondTheShadows
#Ted’s #RadioHour
#Criminal
#TheIncomparable
#FillingTheSink &
#MacPowerUsers
Update. Three past editors of the New England Journal of Medicine (#NEJM) answer the attack on their journal from #RFKJr.
https://www.statnews.com/2025/06/30/rfk-jr-medical-journals-nejm-jama-lancet-editors-respond-medical-journals-ethics/
(#paywalled)
"Kennedy claimed that one of us (Angell) said, 'We are no longer a science journal, we are a vessel for pharmaceutical propaganda.' In fact, what Angell said in a 2009 article was that 'it is simply no longer possible to believe much of the clinical research that is published,' due to researchers’ financial ties with pharmaceutical companies."
The editors also point out that the three journals named by Kennedy happen to have published editorials criticizing the #Trump admin assault of science.
#DefendResearch #Medicine #Pharma #ScholComm #TrumpVResearch #USPol #USPolitics
Man fails to take his medicine—the flesh starts rotting off his leg https://arstechni.ca/2pVY #bloodpressure #casestudy #medicine #Health #Ulcer #NEJM
In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintide–semaglutide resulted in a significantly lower body weight than placebo at 68 weeks. #NEJM Reference www.nejm.org/doi/full/10....
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes. #NEJM "zimislecel can restore physiologic islet function" Reference www.nejm.org/doi/full/10....
Man’s health crashes after getting donated kidney—it was riddled with worms https://arstechni.ca/YU3E #MassachusettsGeneralHospital #Strongyloidesstercoralis #parasiticworms #strongyloides #infection #Health #NEJM
Un nuevo agonista selectivo de los receptores tipo 2 de #Orexina que se administra por vía oral es eficaz para combatir la #narcolepsia, e incluso llega a causar #insomnio como efecto colateral 😄
#Oveporexton #Narcolepsy #Orexin #Neurology #Neurología #SleepMedicine #MedicinaDelDormir #NEJM
It reminds me of #AtlasShrugged.
“We are probably going to stop publishing in the Lancet, the New England Journal of Medicine (#NEJM), #JAMA and those other journals because they are all corrupt."
Kennedy said agencies within the #HHS will create their own “in-house” journals. “They are going to become the preeminent journals, because if you get #NIH funding it is anointing you as a good, legitimate scientist,” he said.
https://thehill.com/policy/healthcare/5322269-robert-kennedy-jr-bans-medical-journals/
Exercise improves colon cancer survival, high-quality trial finds https://arstechni.ca/eba6 #clinicaltrial #coloncancer #exercise #aerobic #Health #NEJM #MET
Personalized Gene Editing to Treat an Inborn Error of Metabolism. #NEJM #TIC2025 www.nejm.org/doi/full/10....
@chema
Oh, MAN, I miss the early Internet days.
In 1991 or '92, I brought a tractor-fed dot-matrix printout about 8-10 pages long of a #NewEnglandJournalOfMedicine #NEJM article/study that was possibly related to my malady, to my #Cardiologist, & he was genuinely appreciative.
I'd used #gopher to find it. Or was it #archie ?
Can you imagine a Dr these days paying ANY attention to something I printed off the Internet today?
"Robert F. Kennedy Jr., the nation’s health secretary, singled out N.E.J.M in an interview with the “Dr. Hyman Show” podcast last year as an example of a medical journal that has participated in “lying to the public” and “retracting the real science.”
. . .
“I’m going to litigate against you under the racketeering laws, under the general tort laws,” he said. “I’m going to find a way to sue you unless you come up ...”"
#RFKJr, #Trump’s *#health* secy, singled out #NEJM in an interview w/the “Dr. Hyman Show” podcast last year as an example of a #medical journal that has participated in “lying to the public” & “retracting the real science.”
Andrew Nixon, a spox for the #HHS, declined to comment on whether RFKJr had any involvement w/the letters.
In the interview, RFKJr said he would seek to prosecute medical journals under federal anti-corruption laws.
Amanda Shanor, a #FirstAmendment expert at the University of Pennsylvania, said the information published in reputable #medical journals like #NEJM is broadly protected by the #Constitution.
In most cases, journals have the same robust rights that apply to newspapers — the strongest the Constitution provides, she added.
#law #censorship #democracy #Trump #AbuseOfPower #authoritarianism #tyranny #dictatorship #AntiIntellectualism #science #medicine
