Repetitive transcranial magnetic stimulation alleviates glial activation through suppressing HMGB1/TLR4 pathway in a rat model of Parkinson’s disease [2023]
https://doi.org/10.1007/s11033-023-08561-8
"This study showed that rTMS might be a promising method for alleviating neuroinflammation in PD rat models, and the effects might be mediated through the downregulation of the HMGB1/TLR4 pathway."
.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury [Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity, #neuroinflammation, and #cerebrovascularbreakdown associated with #stroke and #trauma.[105]
https://pmc.ncbi.nlm.nih.gov/articles/PMC5938896/
#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana
#Streeck 🙏 #NinaWarken 🙏
Herr #Merz #Söder #Klingbeil 😀 #Cannabis
![Phytocannabinoids CBD and Δ9-THC
In addition to the phytocannabinoid Δ9-THC, it is estimated that the cannabis plant consists of over 400 chemical entities, of which more than 60 of them are phytocannabinoid compounds. Some of these compounds have been identified as acting uniquely on both CB1 and CB2 receptors separately and simultaneously, and/or to inhibit or activate receptor functions. CBD, like Δ9-THC, is a major phytocannabinoid accounting for up to 40% of the plant's extract. CBD was first discovered in 1940 more than 20 years before Δ9-THC.[104,105] Until recently, Δ9-THC dominated cannabis research. All classes of phytocannabinoid compounds found in marijuana and hemp, including Δ9-THC and CBD, are derived from various changes to base molecular structure of cannabigerol-type compounds [Figure 1].[34,49]](https://files.mastodon.social/media_attachments/files/115/451/684/710/243/698/original/5232140f38ba5b8c.png)
Myeloid cells drive #neuroinflammation in #MultipleSclerosis by promoting immune activation in the #CentralNervousSystem. This study identifies SLAMF5 as a key myeloid receptor that regulates this process, showing that its blockade reduces disease progression @PLOSBiology https://plos.io/3Vb7xhx
Circadian Harmony: Aligning Sleep-Wake Cycles for Brain Health
#SleepScience #BrainHealth #CircadianRhythm #SleepStages #Memory #Neuroinflammation #Glia #Microglia #Neurodegeneration #Melatonin #Serotonin #SleepBetter
#COVID19-associated #neuroinflammation and #astrocyte death in the #brain linked to ORF3a-induced activation of Sur1-mediated ion channels, https://etidiohnew.blogspot.com/2025/08/covid19-associated-neuroinflammation.html
Neuroinflammation and Oxidative Stress: How Science is Helping Your Brain
#BrainHealth #Neuroscience #HydrogenTherapy #OxidativeStress #Neuroinflammation #BrainRecovery #NeuroScience #MentalHealth #InnovativeMedicine #Neuroprotection
Inflammation, Mitochondria, and Mood: The Biological Roots of Mental Health
#MentalHealth #Neuroscience #BrainScience #Neurotransmitters #Mitochondria #Neuroinflammation #MentalWellness #BiologyOfTheMind #Psychology #HealthScience
The Brain’s Response to Injury: Proteins, Immune Cells, and Structural Changes
#BrainHealth #ConcussionRecovery #NeuroScience #TraumaticBrainInjury #TauProteins #Neuroinflammation #BrainAnatomy #AutoimmuneBrain #BrainResearch #MentalHealthMatters
Understanding Brain Trauma: Cellular Responses and Molecular Cascades
#BrainInjury #Neuroinflammation #TraumaticBrainInjury #Microglia #Astrocytes #BloodBrainBarrier #Neuroregeneration #BrainHealth #Neuroscience #BrainRecovery
From Trauma to Treatment: Navigating Brain Injury and Inflammation
#BrainInjury #Neuroinflammation #Concussion #BrainHealth #Microglia #NeuroScience #BrainRecovery #Neurodegeneration #MentalHealth #NeuroscienceResearch
Understanding CTE: The Long-Term Effects of Repeated Head Injuries
#BrainHealth #CTE #TraumaticBrainInjury #Neurodegeneration #BrainScience #HeadInjury #Neuroinflammation #TauProteins #BrainResearch #ProtectYourBrain
When Brain Balance Tips: Understanding Neuroinflammation After Head Injuries
#BrainHealth #Microglia #Neuroinflammation #Neurodegeneration #Alzheimers #Parkinsons #BrainScience #Neuroscience #BrainAging #Neurobiology #ProteinAggregates #BrainRepair #Neuroimmunology #BrainCells #CognitiveHealth
Sleep, Stress, and Brain Health: The Intricate Balance of Your Mind's Support Systems
#BrainScience #Neuroscience #GlymphaticSystem #BrainHealth #Neurobiology #SleepAndMemory #Neuroinflammation #BrainSupportSystems #MindAndBody #BrainResearch
Tryptophan and the Kynurenine Pathway: Metabolic Routes Impacting Mood and Neurodegeneration
#BrainChemistry #Neuroimmune #KynureninePathway #GutBrainAxis #Neuroinflammation #Microglia #Astrocytes #Neurodegeneration #OxidativeStress #MentalHealth #BrainHealth #Metabolism #NervousSystem #DietAndBrain #Neuroscience
The Chemistry of Mood: Serotonin, Tryptamine, and Neurotransmitter Regulation
#Neurochemistry #BrainHealth #GutBrainAxis #Tryptophan #Serotonin #Microbiome #Neuroinflammation #Toxins #BloodBrainBarrier #BrainRecovery #Neuroscience #MentalHealth #CellularBiology #BrainProtection #MolecularScience
AHRs and Microbiome: The Tiny Guardians of Your Brain-Gut Connection
#BrainAndGut #Microbiome #AHR #Neuroscience #GutBrainAxis #Neurobiology #MentalHealth #VascularHealth #Mitochondria #Neuroinflammation #StressAndHealth #BiologyExplained #HealthyMindBody
Inside the Brain: Exploring Neurotransmitters, Pathways, and Neuroimmune Interactions
#BrainChemistry #Neuroscience #Neurotransmitters #NeuralCircuits #Dopamine #Serotonin #Neuroinflammation #Neurodegeneration #BrainHealth #Neuroplasticity
Neurons, Glia, and Blood Vessels: The Complex City of the Brain
#BrainHealth #Neuroscience #AlzheimersDisease #Neuroinflammation #Microglia #CognitiveHealth #Neurodegeneration #BrainResearch #NeurotrophicFactors #HealthyBrain #MindAndMemory #BrainScience #NeuralNetworks #BrainCare #Neuroprotection
The Brain’s Tiny Guardians: Microglia and Neuroinflammation Explained
#Microglia #Neurodegeneration #BrainHealth #Alzheimers #Parkinsons #Neuroinflammation #CognitiveHealth #BrainScience #Neuroscience #Neurotherapy
From Gut Microbes to Mood: The Science Behind Your Brain’s Health
#GutBrainAxis #MicrobiomeScience #Neuroinflammation #MentalHealthMatters #GutHealth #BrainWellness #Microbiota #Neurotransmitters #StressAndMood #ImmuneSystem #Neuroplasticity #Antidepressants #GutBrainConnection #MindBodyBalance
