Kumar et al. show how caspase-8 adapted to interact with the adaptor ASC, enabling PANoptosome formation and PANoptosis, key processes in inflammation and host defense.

🔗 doi.org/10.1093/molbev/msaf096

#evobio #molbio #immunity #PANoptosis

@cilib @SFB1403 there's only one ptosis and it's #PANoptosis /s