#SarsCOV2

2025-06-29
datum (n=1)datum@zeroes.ca
2025-06-28

She refers to the high quality data from "Brain imaging before and after COVID-19 in UK Biobank"

reduction in grey matter thickness and tissue contrast [...] greater changes in markers of tissue damage [...] and a greater reduction in global brain size in the SARS-CoV-2 cases [2]

[2] medrxiv.org/content/10.1101/20

#COVID #COVID19 #SARSCoV2 #CovidIsNotOver #LongCOVID #BrainFog #BrainScience #Brain

datum (n=1)datum@zeroes.ca
2025-06-28

MD in the UK:

The amount of people I know who now have cognitive issues is staggering. Young, old, it doesnt matter. These are ‘non long Covids’. Biobank called it early- loss of grey matter/reduced volume. People making mistakes everywhere, can’t remember simple lists, can’t find words etc [1]

Don't try and say this doesn't ring a bell, if you live in a community of more than 10.

[1] Dr. Taylor, bird.makeup/users/drclairetayl

#COVID #SARSCoV2 #COVID19 #CovidIsNotOver #CovidCompetent #LongCOVID

datum (n=1)datum@zeroes.ca
2025-06-28

@offby1 aaaargh and in BC, dailyhive.com/vancouver/canada

we already had wastewater indicating an incoming wave of some size

not looking forward to the wastewater heat map in the coming weeks, which will almost certainly have a bright area in Vancouver which then diffuses to the rest of the province

COVID-19 sniffer dogs at disembarkation points would be highly protective but nooooo that'd cost upwards of $1000/day per dog and handler, which is a full 25% of the cost of a hospitalized person in BC. Can't have prevention or avoidance, gotta overload our HCWs and healthcare system!

#BCPoli #COVID #COVID19 #tourism #SARSCoV2 #CovidIsNotOver

2025-06-28

#FYI #USA #MicrobeTV #TWiV #ThisWeekInVirology #DanielGriffin #VincentRacaniello #infectiousdiseases #vaccinate #vaccines #influenza #polio #RSV #covid19 #covid #sarscov2 #NB181

TWiV 1230: Clinical update week 28. Jun 2025

Business as usual: RFKjr lying, targeting to kill childrend and the vulnerable, CDC has new antivaxx working groups, while infectious diseases spread and getting worse -.-

youtube.com/watch?v=lvjItbi_6sQ

Ms. Opossum graphs COVID data.ratnegative@zeroes.ca
2025-06-27

UPDATED: #BC #SARSCoV2 variants.

Of 63 samples from 5/18 - 5/25 (vs. 63, 5/11 - 5/17; 39, 5/4 - 5/10):
NB.1.8.1.* (incl. PQ.*): 49.2% (⬆️ 30.2%; ⬆️ 15.4%)
XFG.*: 6.4% (⬆️ 4.8%; ⬆️ <4%)
LP.8.1.1.* (incl. NY.*): 22.2% (⬇️ 44.4%; ⬇️ 56.4%)

ratnegative.tumblr.com/BCVaria #COVID19

----------

Of the samples collected in B.C. on these weeks, the prevalence of significant variants/lineages are as follows:

- 5/18 - 5/25 -
• NB.1.8.1.* (incl. PQ.1, ".2, ".8, ".10, ".15): 49.2%
• XEC.* (incl. XEC.4.5, ".11.1, ".32.1, "34): 7.9%
• LP.8.1.* (incl. LP.8.1.1.*, NW.1.2, PF.2): 25.4%
→ LP.8.1.1.* (incl. NY.12): 22.2%

- 5/11 - 5/17 -
• NB.1.8.1.* (incl. PQ.1, ".2, ".5, ".6, ".15): 30.2%
• XEC.* (incl. XEC.2, ".4.1.1): 3.2%
• LP.8.1.* (incl. LP.8.1.1.*, NW.1.*): 54%
→ LP.8.1.1.* (incl. NY.2, ".3, ".9, ".13): 44.4%

X.X.* in text = X.X & descendants.

X.X.* in graph = all descendants of X.X, except for ones that have their own segment of the week’s bar. Please see "Notes on Usage" section.

Ms. Opossum graphs COVID data.ratnegative@zeroes.ca
2025-06-27

UPDATED: Northern Health est.'d #COVID19 cases, extrapolated from #PrinceGeorge #wastewater #SARSCoV2 load.

According to #BCCDC ww. data: on average, from 6/12 - 6/18, there would've been 12 cases/day in Northern Health (⬇️ 19, 6/5 - 6/11).

ratnegative.tumblr.com/BCWaste 5/5

Ms. Opossum graphs COVID data.ratnegative@zeroes.ca
2025-06-27

UPDATED: Interior Health est.'d #COVID19 cases, wastewater #SARSCoV2 load.

According to #BCCDC ww. data: on average, from 6/13 - 6/19, there would've been 44 cases/day in Interior Health (⬆️ 39, 6/6 - 6/12).

ratnegative.tumblr.com/BCWaste 4/5

Ms. Opossum graphs COVID data.ratnegative@zeroes.ca
2025-06-27

UPDATED: Island Health est.'d #COVID19 cases, wastewater #SARSCoV2 load.

According to #BCCDC ww. data: on average, from 6/13 - 6/19, there would've been 47 cases/day in Island Health (〰️ 45, 6/6 - 6/12).

ratnegative.tumblr.com/BCWaste 3/5

Ms. Opossum graphs COVID data.ratnegative@zeroes.ca
2025-06-27

UPDATED: Metro #Vancouver est.'d #COVID19 cases, wastewater #SARSCoV2 load.

According to #BCCDC ww. data: on average, from 6/12 - 6/18, there would've been 179 & 545 cases/day in the Van. Coastal & Fraser HAs (⬇️ 216 & ⬇️ 619, 6/5 - 6/11).

ratnegative.tumblr.com/BCWaste 2/5

Ms. Opossum graphs COVID data.ratnegative@zeroes.ca
2025-06-27

🧵UPDATED: #BritishColumbia est.'d #COVID19 cases, the same per 100,000 pop. by health authority.

According to #BCCDC wastewater #SARSCoV2 data: on average, from 6/12 - 6/18, there would've been 827 cases/day in #BC (⬇️ 935, 6/5 - 6/11).

ratnegative.tumblr.com/BCWaste 1/5

2025-06-27

alhora, depenent de molts factors i autors. Com gairebé sempre no serà malevolència sinó simple i planera incompetència. #Origen #CoVID19 #SARSCoV2

2025-06-27

però el #labaccident no era gens descartable. Però @WHO no arriba... al fons de l'assumpte i encara valida la hipòtesi que fos a través del menjar congelat, una hipòtesi que unicament contenta als xinesos, que així poden arguir que va venir de fora de les seves fronteres. És, amb molt, la hipotesi més inversemblant sobre la taula. #SARSCoV2 #SAGO

"I hate to tell you but I told you". Les errades de #bioseguretat són possibles, i les #AvaluacionsDeRisc poden suportar moltes coses i poques,...

JNSLCTJNSLCT
2025-06-26

Neuroimmune pathophysiology of long COVID
Janna K. Moen PhD, Christopher A. Baker PhD, Akiko PhD

.. In this review we provide a comprehensive overview of the current body of literature on neurological manifestations of SARS-CoV-2 infection and Long COVID, with an emphasis on neuroimmune mechanisms drawn largely from autopsy studies and animal models. ..

onlinelibrary.wiley.com/doi/10

2025-06-25
Screenshot of abstract
2025-06-25

pmc.ncbi.nlm.nih.gov/articles/ “The overall SAR of 37.2% was lower in the contacts of both vaccinated index cases (34.9% vs. 63.2%; p = 0.014) and index cases with a previous SARS-CoV-2 infection history (27.0% vs. 46.3%; p = 0.002). Index case vaccination showed a protective effect against infection for their household contacts (aOR = 0.21; 95%). The household SAR was high when the #Omicron variant circulated. Vaccinated index cases were less likely to transmit #SARSCoV2 to their contacts.”

2025-06-25

From Hungary:

"we report for the first time the activation of P2X7 receptors following #SARSCoV2 infection is involved in the induction of anxiety & mood alterations through inflammatory pathways"

sciencedirect.com/science/arti

Image from Science for ME update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #CovidIsNotOver
@auscovid19 #auscovid19

Neuropharmacology
Targeting P2X7 mitigates neurobehavioural alterations in a mouse model of post-acute sequelae of SARS-CoV-2 infection — Szabó et al.
"we report for the first time that the activation of P2X7 receptors following SARS-CoV-2 infection is involved in the induction of anxiety and mood alterations through inflammatory pathways."

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