Lmst

Chiu et al. used assayed cells expressing New World monkey ACE2 to show that later-evolving strains of SARS-CoV-2 acquired infectivity. Human-driven evolution of viral cells enhanced the potential for human-to-non-human transmission.

🔗 https://doi.org/10.1093/molbev/msaf281

#evobio #molbio #sarscov2

Zum vorigen Post: Viele Atemwegserkrankungen sagt das RKI, vor allem durch "Rhinoviren und #SarsCoV2". Und empfiehlt die Grippeimpfung. Was vernünftig ist.
Sich gegen COVID impfen zu lassen, findet das RKI dagegen anscheinend überflüssig?

De Maio et al. processed >2 million genomes to show that certain multinucleotide mutations are highly recurrent in SARS-CoV-2, including some that have independently occurred hundreds of times across all SARS-CoV-2 lineages.

🔗 https://doi.org/10.1093/molbev/msaf272

#evobio #molbio #sarscov2

🤧 Die Zahl der akuten respiratorischen Erkrankungen ist laut #GrippeWeb im Vergleich zur Vorwoche angestiegen und liegt nun auf einem hohen Niveau!

📊 Seit Monaten zirkulieren vor allem Rhinoviren und #SarsCoV2. #Influenzaviren wurden in den vergangenen Wochen noch selten, aber in ansteigender Häufigkeit nachgewiesen.

Alle Personen, für die die STIKO die Grippeschutzimpfung empfiehlt, sollten sich impfen lassen.

💪 Habt ihr euch in dieser Saison schon gegen #Grippe geimpft?

Zhang et al. passaged SARS-CoV-2 virus in seven cell lines derived from four tissues across five mammalian species, uncovering host-specific selective forces in shaping SARS-CoV-2 evolution.

🔗 https://doi.org/10.1093/molbev/msaf274

#evobio #molbio #sarscov2

From China

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID

https://www.sciencedirect.com/science/article/pii/S0010482525016701

Screenshot from latest Science for ME weekly update

#LongCovid #Covidlung @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Longitudinal assessment of pulmonary perfusion and ventilation defects in long COVID: A one-year study using phase-resolved functional lung (PREFUL) MRI — Ouyang et al.
"We found ventilation defects normalizing by six months, while perfusion defects persisted for up to one year. Severe perfusion defects at the acute phase were associated with a higher risk of long COVID, persistent dyspnea, and fatigue."

From the US

Clinical, Radiographic, and Physiological Correlates of Post-COVID-19 Dyspnea in Military Health System Beneficiaries

https://dx.doi.org/10.1093/ofid/ofaf633

Screenshot from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

Clinical, Radiographic, and Physiological Correlates of Post-COVID-19 Dyspnea in Military Health System Beneficiaries: Results From the Chronic Impairment With Pulmonary Symptoms (ChIPS) Sub-study — Goertzen et al.
"Overall, this study demonstrates both subjective and objective differences between those with ongoing dyspnea following COVID-19 infection that are not explained by standard investigations typically ordered in clinical care for chronic dyspnea."

From Germany:

"this study provides robust evidence of significant cognitive impairments in #PASC patients, with attention, working speed, and lexical fluency being the most commonly affected domains."

https://link.springer.com/10.1007/s00406-025-02144-3

Screenshot from latest Science for ME weekly update

@longcovid
#LongCovid #PwLC #postcovid #postcovid19 #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver @novid #novid

Cognitive impairment, depression, and fatigue in post-COVID and post-vaccination syndrome: a large-scale cross-sectional study — Hanc et al.
"this study provides robust evidence of significant cognitive impairments in PASC patients, with attention, working speed, and lexical fluency being the most commonly affected domains."

Evidence for a severe cognitive subgroup in a comprehensive neuropsychological Post-COVID-19 syndrome classification

https://www.nature.com/articles/s41598-025-25453-y

Screenshot from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #auscovid19 #CovidIsNotOver

@novid #novid

#LongCovid #Prävention #CovidlsAirborne #TeamVorsicht #C19 #SARSCoV2 #MECFS #ME #CFS #FFPMaske #Luftreiniger #CleanAir #SaubereLuft #Prävention #CovidIsntOver 😳😳😳 Ich hoffe, das ist ein Fakefoto😬 Quelle: Facebook

Hr. Dr. Kleinschnitz und Frau Dr. Alena Buyx auf einem Foto.
Quelle: Facebook

Der Tag beginnt heute zum Glück nicht mit Arbeit, sondern mit dem Termin beim Straßenverkehrsamt um den Führerschein zu erneuern und dann mit dem Lebenssaft #SarsCoV2- und Grippeschutzimpfung (das dann aber beim Hausarzt 😆)

Mientras, la vigilancia epidemiológica se ha reducido,
el #SARSCoV2 sigue mutando, recobimándose y evolucionando a velocidad y en cantidad.

Eso suena a que la evolución del virus y la vigilancia epidemiológica están teniendo una correlación negativa que podría estar creciendo en magnitud. :ablobheadshake:

Con tanto profesional de la salud que ha tenido covid repetidamente, el deterioro cognitivo para observar, investigar, analizar, extraer conclusiones lógicas y traducir los datos a información se ha reducido grandemente.
#SARSCoV2

New in Nature today, "A systematic review and meta-analysis of the impact of vaccination on prevention of long COVID", found boosters give ~23% protection against Long COVID in the Omicron era:

The pooled odds ratio (OR) of long COVID in those
vaccinated (any dose) versus unvaccinated is 0.77 (95% confidence interval [CI] 0.70–0.85; p < 0.0001; 10 studies).
primary course vaccination versus unvaccinated (OR 0.81; 95% CI 0.79–0.83; p < 0.0001; 3 studies),
booster vaccination versus unvaccinated (OR 0.74; 95% CI 0.63–0.86; p = 0.0001; 4 studies),
booster vaccination versus primary course vaccination (OR 77; 95% CI 0.65–0.92; p = 0.0044; 3 studies).
These findings indicate that booster vaccination can provide additional protection against long COVID,

https://www.nature.com/articles/s41467-025-65302-0 h/t @kcarruthers

#COVID #COVID19 #SARSCoV2 #PublicHealth #LongCOVID #Vaccines