@razvan @BakkeHK Not at all. The purpose of using #albumin in #SepticShock is precisely to prevent or mitigate #glycocalyx damage. If oncontic pressure gradient was the purpose, any synthetic colloid would do the job (actually, they won’t, because of the altered endothelial layer, as you suggested)
https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-020-00697-1
https://link.springer.com/article/10.1007/s00134-022-06740-y