#Serological

Giuseppe MichieliGMIK69@mstdn.science
2025-12-21
Giuseppe MichieliGMIK69@mstdn.science
2025-06-06

#Serological insights into #MERS-CoV dynamics of #antibody responses during acute and convalescent phases and their clinical relevance for #diagnostics and immunity, etidiohnew.blogspot.com/2025/0

Giuseppe MichieliGMIK69@mstdn.science
2024-10-17

#Serological analysis in #humans in Malaysian #Borneo suggests prior exposure to #H5 avian #influenza near migratory #shorebird habitats

Source: Nature Communications, AbstractCases of H5 highly pathogenic avian influenzas (HPAI) are on the rise. Although mammalian spillover events are rare, H5N1 viruses have an estimated mortality rate in humans of 60%. No human cases of H5 infection have been reported in Malaysian Borneo, but HPAI has circulated in poultry and…

etidioh.wordpress.com/2024/10/

Giuseppe MichieliGMIK69@mstdn.science
2024-07-27

A Computationally Optimized Broadly Reactive #Hemagglutinin and #Neuraminidase #Vaccine Boosts #Antibody-Secreting Cells and Induces a Robust #Serological Response, Preventing #Lung #Damage in a Pre-Immune #Model pubmed.ncbi.nlm.nih.gov/390663

... the combination of #H2, #H5, #H7, #N1, and #N2 #COBRA #antigens presents a potential for the formulation of a universal influenza virus vaccine.

Giuseppe MichieliGMIK69@mstdn.science
2024-07-27

#Dynamics of #influenza #transmission in vampire #bats revealed by longitudinal monitoring and a large-scale anthropogenic #perturbation, BioRxIV: biorxiv.org/content/10.1101/20

Mechanistic #models fit under a Bayesian framework, which enabled joint inference from #serological and #molecular data, showed that common vampire bats maintain BIV independently of the currently assumed fruit bat #reservoir through immune waning and seasonal #transmission pulses.

Giuseppe MichieliGMIK69@mstdn.science
2024-06-07

Large-Scale #Serological #Survey of #Influenza A Virus in South #Korean Wild #Boar (Sus scrofa) pubmed.ncbi.nlm.nih.gov/388426

Detected subtypes included 23 cases of pandemic 2009 #H1N1, six of human seasonal #H3N2, three of classical swine H1N1, 13 of triple-reassortant swine #H1N2, seven of triple-reassortant swine H3N2, and seven of swine-origin H3N2 variant. Notably, none of the serum samples tested positive for avian IAV subtypes #H3N8, #H5N3, #H7N7, and #H9N2 or canine IAV subtype H3N2.

Giuseppe MichieliGMIK69@mstdn.science
2023-06-08

''Our experimental studies showed that these #H3N8 viruses were transmissible in #ferrets, and #serological data suggest that the #human population lacks effective immunological protection against it. With its wide geographical distribution and continuing evolution in chickens, other spillovers to humans can be expected and might lead to more efficient transmission in humans.''

Giuseppe MichieliGMIK69@mstdn.science
2022-11-29

Dumont, R., Richard, V., Lorthe, E. et al. A population-based #serological study of post- #COVID #syndrome #prevalence and #risk factors in #children and #adolescents. Nat Commun 13, 7086 (2022). doi.org/10.1038/s41467-022-346

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