Lmst

India has launched BIRSA 101, the nation’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease, marking a major leap in genomic medicine and affordable healthcare. https://english.mathrubhumi.com/lifestyle/health/india-crispr-gene-therapy-sickle-cell-disease-n4em93uz?utm_source=dlvr.it&utm_medium=mastodon #SickleCellDisease #CRISPRIndia #Birsa101 #GenomicMedicine

Review Salmonella and Staph aureus as key pathogens in sickle cell osteomyelitis. #Osteomyelitis #SickleCellDisease #USMLE #InfectiousDiseases #MedicalEducation #Microbiology

https://mymedschool.org/portfolio/u01-20-016-osteomyelitis-in-sickle-cell-disease/?utm_source=mastodon&utm_medium=jetpack_social

NHS alert over often symptomless 'trait' that may be serious if inherited by children

https://fed.brid.gy/r/https://www.mirror.co.uk/news/health/nhs-alert-over-often-symptomless-35996293

Orioles blood drive raises awareness for sickle cell disease https://www.rawchili.com/mlb/320069/ #AmericanRedCross #awareness #Baltimore #BaltimoreHospital #BaltimoreHospitals #BaltimoreOrioles #BaltimoreOrioles #Baseball #blood #BloodDonations #BradChambers #condition #decision #Donation #ExecutiveVicePresident #Health #hospital #hospitals #HowToDonateBlood #ManyPeople #maryland #medstar #MedstarHealth #MLB #news #Orioles #OriolesBloodDrive #patient #SickleCell #SickleCellDisease

𝗪𝗼𝗿𝗹𝗱 𝗦𝗶𝗰𝗸𝗹𝗲 𝗖𝗲𝗹𝗹 𝗗𝗮𝘆 – 𝟭𝟵 𝗝𝘂𝗻𝗲 𝟮𝟬𝟮𝟱

𝗧𝗵𝗲𝗺𝗲: Global Action, Local Impact: Empowering Communities for Effective Self-Advocacy

𝗪𝗵𝘆 𝗜𝘁 𝗠𝗮𝘁𝘁𝗲𝗿𝘀:
Sickle cell disease (SCD) affects over 300,000 births globally every year, with a large burden in low- and middle-income countries like India. It disproportionately impacts marginalized communities, especially tribal populations who face socioeconomic challenges. Awareness and early diagnosis are crucial to reduce complications and improve quality of life.

𝗔𝗯𝗼𝘂𝘁 𝘁𝗵𝗲 𝗗𝗮𝘆:
World Sickle Cell Day was established by the United Nations in 2008 to spotlight sickle cell disease as a major genetic health concern. The day promotes public education, encourages screening, and supports affected individuals and families worldwide.

𝗞𝗲𝘆 𝗣𝗼𝗶𝗻𝘁𝘀 𝘁𝗼 𝗦𝗵𝗮𝗿𝗲:
- Sickle cell disease is a genetic blood disorder causing abnormal red blood cells that affect oxygen delivery.
- Early diagnosis through newborn screening and blood tests is vital.
- Communities need empowerment to advocate for better healthcare access and support.
- Knowing your sickle cell trait status helps in family planning and prevention strategies.

𝗛𝗼𝘄 𝗬𝗼𝘂 𝗖𝗮𝗻 𝗛𝗲𝗹𝗽:
- Get tested or encourage others to get screened, especially before pregnancy.
- Support local and global awareness campaigns.
- Share accurate information about SCD symptoms, treatment, and prevention.
- Advocate for better healthcare policies and resources for affected communities.

Let’s unite on 19 June 2025 to empower communities and create lasting change for people living with sickle cell disease.

#WorldSickleCellDay #SickleCellAwareness #SickleCellDisease #GlobalActionLocalImpact #EmpowerCommunities #GetTested #HealthEquity #GeneticDisorders #EarlyDiagnosis #SupportSickleCellPatients #HealthForAll #BloodDisorders #KnowYourStatus #SCABPharmacy

Africa: Sickle Cell Disease Remains a Challenge in Africa!: [The Point] Sickle cell disease refers to a group of inherited blood disorders with symptoms like anaemia and blocked blood vessels. About 80% of the world's sickle cell disease cases occur in sub-Saharan Africa. Lack of access to comprehensive healthcare in the region adds to the burden of the disease. http://newsfeed.facilit8.network/TLPdqV #SickleCellAwareness #HealthcareForAll #AfricaHealth #SickleCellDisease #HealthEquity

Beam Therapeutics reveals breakthrough sickle cell treatment data at EHA2025, showcasing innovative base editing technology for potential long-term genetic therapy solutions. #Biotech #SickleCellDisease

‘Groundbreaking’ sickle cell disease treatment approved for NHS use in England
Clinical trials find one-time gene therapy exa-cel offers ‘functional cure’ in 96.6% of patients

https://www.theguardian.com/society/2025/jan/31/groundbreaking-potential-cure-for-sickle-cell-in-england-approved-for-nhs-use

#142holdheap #SickleCellDisease #GeneTherapy #Medicine

‘Groundbreaking’ potential cure for sickle cell in England approved for NHS use https://www.theguardian.com/society/2025/jan/31/groundbreaking-potential-cure-for-sickle-cell-in-england-approved-for-nhs-use #Sicklecelldisease #Medicalresearch #Geneediting #Genetics #Society #Biology #Science #Health #UKnews #NHS

Sickle cell retinopathy

In sickle cell disease, widefield fluorescein angiography (FA) is superior for evaluating peripheral ischemia. This imaging modality captures extensive retinal areas, enabling the detection of non-perfusion zones, neovascularization, and other ischemic changes often missed in standard FA. Widefield FA is critical for guiding management strategies, including laser photocoagulation. #SickleCellDisease #WidefieldFA #PeripheralIschemia…

https://retinography.org/sickle-cell-retinopathy-4/

"It was at Barnes that she’d learned people with sickle cell could have children after all. As she started coming here, she’d seen other patients with kids in tow. She hadn’t thought that was possible."

For STAT, Eric Boodman follows a #SickleCellDisease patient as she juggles pain, doubt, and the challenges of a complex disease: https://www.statnews.com/2024/11/11/coercive-care-series-sickle-cell-pregnancy-risks-unwanted-sterilizations

#Longreads #Health #Medicine #Sterilization

Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH
https://www.nhlbi.nih.gov/health/sickle-cell-disease

#GetToKnowSickleCell
#sicklecellanemia
#sicklecelldisease
#sicklecell
#SickleCellTrait
#sicklecellpain
#SCD

"Some stories carry echoes of 'Mississippi appendectomies' of the mid-20th century, in which Black women would go in for a different procedure and wake up to learn that their uterus had been removed."

A STAT #investigation by Eric Boodman on how doctors are pressuring sickle cell patients into unwanted sterilizations: https://www.statnews.com/2024/05/21/sickle-cell-patients-steered-toward-sterilization-for-decades/

#Longreads #Health #SickleCellDisease #Journalism #Doctors

"There’s this counseling, in sickle cell disease in general, when patients are doing something that a clinician doesn’t agree with. I call it the Sickle Cell Death Threat, which is like: "If you don’t do X, you are going to die.'"

Part 1 of @STAT's series on how, for decades, doctors have pushed #SickleCellDisease patients into sterilization:

https://www.statnews.com/2024/05/21/sickle-cell-patients-steered-toward-sterilization-for-decades/

#health #healthcare #medicine #reproductivehealth #SCD #eugenics #HealthEquity

Could gene therapy be a #gamechanger in the fight against #sickle-cell anemia? | DW News

There might be fresh hope for millions of people affected by #SickleCellDisease. In the #US, a new commercially licensed gene #therapy has been administered for the first time to a patient.
It could be a gamechanger in the fight against this disorder of unusually-shaped red #blood cells that can disrupt the victims' blood flow. This leads to severe health complications including #chronic pain and organ damage, which can also be life threatening.
The #genetic condition is found around the world but mainly among people with West or #CentralAfrican backgrounds. According to the World Health Organization 1,000 children are born with the disease every day in Africa. And the existing treatments can be rare and expensive.

https://www.youtube.com/watch?v=YvhidtytB5w

#SickleCellAnemia #GeneTherapy #health #news #Afrika #Afrique #Africa #إفريقيا #tv #DW

While there are numerous caveats, there are now two gene editing therapies available for people with Sickle Cell Disease, and early therapies have been very successful. It's nowhere near cheap at over $2M for one and over $3M for the other, but it's a start I suppose. Only the 1% can afford such therapy for now, but if sanity ever returns to society, I would hope that empathy will eventually win out over profits in the end. #science #crispr #genetherapy #sicklecelldisease https://youtu.be/uHWD8RSw4As

The 20 ‘most painful' health conditions, according to the NHS
https://www.msn.com/en-gb/health/medical/the-20-most-painful-health-conditions-according-to-the-nhs/ar-AA1kSjMR?cvid=0891b67d26254255841cf61460de207b&ocid=winp2fptaskbarhover&ei=7

#Pain
#NHS
#Endometriosis
#SlippedDisc
#Appendicitis
#BrokenBones
#Shingles
#FrozenShoulder
#ClusterHeadaches
#ComplexRegionalPainSyndrome
#CRPS
#HeartAttack
#KidneyStones
#Arthritis
#Gout
#SickleCellDisease
#SickelCell
#Fibromyalgia
#Migraine
#Sciatica
#TrigeminalNeuralgia
#AcutePancreatitus
#StomachUlcer
#PáinAfterSurgery

Sickle cell gene therapies seen as cost effective below $2M threshold —FDA requires 'boxed warning' for CAR-T cancer therapies — Trial raises hopes for simple Alzheimer’s blood test --http://bit.ly/w28kSd #sicklecelldisease #fda #warning #cart #cancer #alzheimers #clinicaltrials #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma

Next in our 'Building Advocacy into Research' collection we have an interview with
@MarieOjiambo, founder of the Sickle Strong Initiative in Kenya & member of @oneSCDvoice
in the US. She is also a Senior Scientific Associate at @CRiverLabs

https://journals.biologists.com/dmm/article/16/12/dmm050629/338280/ #SickleCellDisease