#Transplant

The Good News Network: Positive Stories 24/7goodnewsnetwork.org@web.brid.gy
2025-10-10
2025-10-10

👨‍⚕️ Người đàn ông 71 tuổi được cấy gan lợn đã chỉnh sửa gene vào cơ thể mình. Các bác sĩ Trung Quốc cho biết đây là ca ghép gan động vật vào người đầu tiên, nhằm giải quyết tình trạng thiếu thận và gan. Hiện bệnh nhân đang hồi phục, nhưng vẫn cần theo dõi lâu dài để đánh giá an toàn và hiệu quả.

#yte #health #gan #transplant #medicine #science #Vietnam #China #bácsĩ #y học #ghếpgan #độngvật #geneticediting

vietnamnet.vn/dieu-gi-xay-ra-v

2025-10-10

🩺 171 ngày kỳ diệu sau ca ghép gan lợn biến đổi gene – bệnh nhân đã hồi phục nhanh chóng, mở ra triển vọng mới cho y học ghép tạng.

#yhoạckhông #yte #transplant #ganlợn #geneediting #medicine #health #Vietnam #medicalinnovation

vtcnews.vn/171-ngay-ky-dieu-cu

2025-10-08

ctvnews.ca/vancouver/article/u

“Their research found enzymes that remove present surface layer A and B antigens, and convert them into O type antigens.”

#medicine #Science #transplant

Swapnil Hiremath 🍁🇨🇦hswapnil.medsky.social@bsky.brid.gy
2025-10-03

The decedent model of kidney transplant research now used for….’removing’ the A antigen to transplant into a brain dead recipient with anti-A titres www.nature.com/articles/s41... #NephSky #Transplant

Enzyme-converted O kidneys all...

2025-09-21

A young man meets the 19-year-old kidney donor who saved his life

videovortex.tv/w/nQG9fKDbgRjMf

Swapnil Hiremath 🍁🇨🇦hswapnil.medsky.social@bsky.brid.gy
2025-09-18

Lot of possible badness going on with certain OPOs apple.news/AQIiKWjWvTW6... #NephSky #Transplant

gengar1658 at KillBaitgengar1658@killbait.com
2025-09-05

Early Diagnosis and Liver Transplants Vital for Treating Liver Disease in Children

Liver disease in children is a rare but serious condition that often differs significantly from adult liver diseases. While adult liver problems such as cirrhosis and hepatitis are more common, children's liver issues are more likely to arise from congenital or genetic disorders like biliary atresia... [More info]

Old Man in the Shoejenzi
2025-09-03

Also, did get a organ ? Is that what the discussion was about with them together. Remember he was apart from everyone oddly before the Ukraine invasion - was that because he had an organ replaced?

Open Health AIOpenHealthAI
2025-08-20

CNI nephrotoxicity (tacrolimus/cyclosporine): Immunosuppression – 2 classes: CNI, mTORi (sirolimus), GC (prednisone), purine synthesis inh (azathioprine, MMF) | Calcineurin inhibition → afferent arteriolar vasoconstriction → ↓ renal blood flow → ↑ Cr/BUN + HTN | Histo: Acute → tubular vacuolization; Chronic → obliterative vasculopathy, striped fibrosis, tubular atrophy | Rx: Dose ↓, switch to mTORi (sirolimus)

#2025

Swapnil Hiremath 🍁🇨🇦hswapnil.medsky.social@bsky.brid.gy
2025-07-27

The current HHS wades into the Wild West of OPOs in the organ #transplant industry Let’s hope some good comes out of it rather than a witch-hunt as a lot of badness currently does exist? www.medpagetoday.com/rheumatology...

Yes, HCQ Does Help Preserve Re...

Swapnil Hiremath 🍁🇨🇦hswapnil.medsky.social@bsky.brid.gy
2025-07-16

Pathologies of 🐷 to human kidney transplant 3 patients - from Jayme Locke et al in @ajkd.bsky.social Mesangial IgM/C4 deposits + cellularity seen even preimplantation, endothelial injury, even (viral) inclusion in one case www.ajkd.org/article/S027... #transplant #nephsky #renalpath

Fi gure 1 Case 1 xenografts. (A) Left preimplantation biopsy shows glomerulus with mild increase in mesangial matrix and segmental increase in mesangial cellularity (PASH x20). (B) Right postimplantation biopsy, POD-2, shows diffuse tubular epithelial cell necrosis with loss of nuclei and frequent granular casts. The glomerulus shows rare lumina occluded by fibrin thrombi (arrows); the rest of the capillaries are congested (PASH x20). (C) Left preimplantation biopsy; immunofluorescence shows global granular staining for IgM limited to the mesangium (FITC anti-human IgM). (D) Right preimplantation biopsy shows electron dense immune complex deposits within the expanded mesangium (Uranyl acetate and lead citrate, x4000). (E) Low power of the biopsy in D shows nearly intact foot processes; the mesangial matrix and cellularity is mildly increased, and the glomerular basement membrane appears thin (Urinayl acetate and lead citrate x1600). (F) Right postimplantation biopsy, POD-2, shows severe endothelial cell injury with loss of endothelial cell nuclei; the lumina are completely obliterated by degenerated swollen endothelial cells, fibrin tactoids (arrow) and entrapped fragmented red blood cells; the foot processes are completely effaced (Uranyl acetate and lead citrate, x3200).Figure 2 Case 2 xenografts. (A) Left preimplantation biopsy shows glomerulus with mild increase in mesangial matrix and segmental increase in mesangial cellularity; adjacent arteriole is unremarkable (PASH x20). (B) Left postimplantation biopsy, POD-3, there is moderate to severe acute tubular injury showing luminal dilatation with tubular epithelial cells simplification and frequent casts within injured tubular lumen and interstitial edema; the glomerulus, in addition to mildly increased mesangial matrix and mild mesangial hypercellularity, shows scattered inflammatory cells including PMNs (arrow) within the capillary lumina lined by swollen endothelial cells with segmental partial to near complete obliteration of the peripheral capillary lumina (PASH x20). (C) Left preimplantation biopsy; immunofluorescence shows weak but global granular staining for IgM limited to the mesangium (FITC anti-human IgM). (D) Left postimplantation biopsy, POD-1; immunofluorescence shows strong and global, granular staining for C3 predominantly limited to the mesangium (FITC anti-human C3). (E) Right preimplantation biopsy; the foot processes are nearly intact; the glomerular basement membrane appears thin (Uranyl acetate and lead citrate x3400). (F)Left preimplantation biopsy; and (G) Left postimplantation biopsy, POD-1; there are frequent electron dense immune complex deposits within the expanded mesangium (Uranyl acetate and lead citrate, x5800 and 3400 respectively). (H) Right postimplantatiFigure 3 Case 3 xenografts. (A) Left preimplantation biopsy shows glomerulus with mild increase in mesangial matrix and segmental increase in mesangial cellularity; there is no tubulointerstitial injury (PASH x20). (B) Left postimplantation biopsy, POD-7, the peritubular capillaries (arrows) contain inflammatory cells indicative of peritubular capillaritis; the tubulointerstitium shows moderate acute tubular injury and interstitial edema (PASH x20). (C) Left postimplantation biopsy, POD-3, the C4d stain is negative in the peritubular capillaries (C4d immunohistochemical stain x20). The C4d is focally positive in peritubular capillaries in postimplantation, POD-5 (D) and diffusely positive in postimplantation, POD-7 (E) biopsies (C4d immunohistochemical stain x20). (F) Right postperfusion biopsy; immunofluorescence shows global granular staining for C3, limited to the mesangium (FITC anti-human C3). (G) Right preimplantation and (H) right postperfusion biopsies; the foot processes are nearly intact; the glomerular basement membrane appears thin (Uranyl acetate and lead citrate x2600 and 1450 respectively). (I) Right postperfusion biopsy on higher power shows rare electron dense immune complex deposits (arrow) within the expanded mesangium (Uranyl acetate and lead citrate x7900). (J) Right postimplantation biopsy, POD-7, shows mildly increased mesangial matrix and segmentally swollen endothelial cells; however, no significant foot process effacement is present (Uranyl acetate a
Swapnil Hiremath 🍁🇨🇦hswapnil.medsky.social@bsky.brid.gy
2025-07-15

Importance of reporting cancer outcomes in kidney #transplant In @kireports.bsky.social www.kireports.org/article/S246... #NephSky

Figure 1 Absolute importance of cancer outcomes (a) and relative importance scores (b) stratified by patients/caregivers and health professionals. Legend: (a) Proportion of patients/caregivers (left) and health professionals (right) rating outcomes as critically important (7-9 points, blue), important (4-6 points, orange) or of limited importance (1-3 points, green) on a 9-point Likert scale (absolute importance). (b) Mean relative importance scores for patients/caregivers and HPs from the analysis of the BWS survey. Bars represent the mean preference score with 95% CIs.
2025-07-14

The irony is not lost on me that my 30th #kidney #transplant anniversary is also very close to the 43rd anniversary since all this nonsense started.
No surprise I'm feeling it a little bit.
TX anniversary is 3 weeks tomorrow 😀 :GoodTea:

2025-07-13

Sunday, July 13, 2025

Germany-funded long-range weapons to arrive in Ukraine by late July — Impeccable results: New Skynex video shows Ukrainian forces destroying Russian drones with German gun — Ukraine destroys Russian drone unit after Kherson infant killed, child should never have been a target — “Cut off the head”: Ukrainian intelligence accuses Putin’s favorite brigade of another war crime … and more

activitypub.writeworks.uk/2025

A screenshot from the video of Skynex in action published by Ukraine's Air Force on July 12, 2025

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