#Harmonine is a defense compound produced by the #Asian #ladybeetle #Harmoniaaxyridis
It is an important factor in beetle #immunity and has #BroadSpectrum #antimicrobial #activity #inhibiting the growth of #mycobacteria and demonstrating #multistage #antimalarial activity
The Asian lady beetle uses harmonine as a general hygiene measure, but switches to an effective defense strategy based on dozens of peptides when threatened

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297383/

https://www.mpg.de/7246516/Asian-lady-beetles

Scientists reveal machine learning could accelerate discovery of #antimalarial properties in #plants.

#AI #bioprospecting

https://phys.org/news/2023-05-scientists-reveal-machine-discovery-antimalarial.html

On the worsening #AntiMalarial #DrugResistance in #Africa

#malaria #drugs #artemisinin #PlasmodiumFalciparum #Plasmodium #falciparum #protozoa #Anopheles #mosquito

https://www.dw.com/en/africa-antimalarial-drug-resistance-on-the-rise/a-64306141

Rectal #artesunate, a promising #antimalarial drug, has no beneficial effect on the survival of young children with severe #malaria when used as an emergency treatment in resource-constrained settings.
#Medical #sflorg
https://www.sflorg.com/2022/12/med12202202.html