#basalganglia

Fabrizio MusacchioFabMusacchio
2026-01-09

🧠 New preprint by Greenstreet, Geerts, Gallego, and Clopath on across , , and .

Key idea: supervised learning builds a low-dimensional action embedding, and operates directly in this structured space. This explains generalization, interference, and striatal similarity patterns as geometric consequences, not add-ons.

🌍 doi.org/10.64898/2025.12.19.69

Figure 1: A multi-region model learns structured action representations. (
2025-11-03

Songbird connectomics, from my colleague Joergen Kornfeld:
songbird-connectomics.org/

Includes the first connectome of basal ganglia.

Three key papers:

"The songbird basal ganglia connectome", Rother et al. 2025 (Kornfeld lab)
biorxiv.org/content/10.1101/20

"An anatomical substrate of credit assignment in reinforcement learning", Kornfeld et al. 2025 (with Michael Fee as senior author)
biorxiv.org/content/10.1101/20

"Songbird connectome reveals tunnelling of migratory neurons in the adult striatum", Shvedov et al. 2025 (B.B. Scott's lab)
biorxiv.org/content/10.1101/20

#neuroscience #connectomics #ZebraFinch #songbirds #BasalGanglia

2025-10-31

the first songbird #basalganglia #brain connectome:
-8,500 automated neuron reconstructions
-20 million synapses
-16 cell types
songbird-connectomics.org/

RationizedInsanity🏳️‍🌈🇺🇦🇨🇦🇬🇱🇵🇸RationalizedInsanity
2025-09-30

Something I always wondered about people with and :

We're almost always empaths.

The part of our brain - the - responsible for is slightly larger than usual while the part of our brain in our regulating motor planning/control, has faulty neuro-pathways and shrunken parts.

More connections to the PFC as an adaptation, resulting in glitchy motor controls but perhaps very deep emotions.

2025-01-28

#BasalGanglia are critical for decision-making, but how are their subregions coordinated? @nadjagingjehli &co show how the different subregions regulate #decision dynamics under varying degrees of conflict & uncertainty in a perceptual decision task #plosbiology plos.io/3WC13cq

Task-evoked neuronal response. Left: Stimulus-induced mean changes (solid/dotted bold lines) in theta power (4–8 Hz) by condition. Right: Time frequency plots show a task-evoked increase in LFO power (averaged across channels) relative to baseline. Spectra are shown for high minus low conflict (averaged across coherence) aligned to stimulus onset (left panel) and response (right panel) for each basal ganglion component (STN – subthalamic nucleus; GPe – globus pallidus externus; GPi – globus pallidus internus).
Dr. Marie McNeelyPhDMarie@qoto.org
2024-06-16

Dr. Aryn Gittis shared insights about basal ganglia circuits and the new deep brain stimulation protocol that she is developing which leverages knowledge of these circuits and neuron firing patterns to provide longer-lasting effects.

michaeljfox.org/podcast/episod

#basalganglia #brain #neuro #neuroscience #research #science #podcast #podcasts #scicomm #sciencecommunication #parkinsons #ParkinsonsDisease #PD #DBS #BrainStimulation

The podcast title is shown in the top left of the image: "The Parkinson's Research Podcast: New Discoveries in Neuroscience. There is a line art depiction of a microcope to the right. The Michael J. Fox Foundation for Parkinson's Research Logo is below on the left. At the bottom, in white text on an orange background, it says "Episode 16 with Dr. Aryn Gittis". Below in dark blue text on a white background it says "Studying Basal Ganglia Circuits and Developing Deep Brain Stimulation Protocols for Longer-Lasting Effects".
Le Néandertal se sent las, lasHydrePrever@mathstodon.xyz
2023-05-05

@jaztrophysicist @LegalizeBrain @ciredutempsEsme et puis ce #basalGanglia, quelle frime ! Les gens simples disent #lizardBrain #YLC

Alessandro D'Ausilioaledaus@neuromatch.social
2023-04-03

#NewPaper #Neuroscience

Another cool #Anatomy paper on the connectivity between #BasalGanglia and the #Cerebellum

Here some quotes:

"Neural processing in the basal ganglia is critical for normal movement.
...
Many believe that the basal ganglia influence movement via thalamic projections to motor areas of the cerebral cortex and through projections to the cerebellum, which also projects to the motor cortex via the thalamus.
...
However, lesions that interrupt these thalamic pathways to the cortex have little effect on many movements, including limb movements.
...
In this report, we describe several brainstem pathways that connect basal ganglia output to the cerebellum via nucleus reticularis tegmenti pontis (NRTP).
...
The basal ganglia could ... alter movements via descending projections of the cerebellum.
...
Pathways through NRTP ... may underlie deficits associated with basal ganglia disease."

link.springer.com/article/10.1

#Parkinson #MotorControl #MovementDisorders #Neurology

2023-03-06

Interestingly, M1 and SMA responses related to better motor performance and the cortical distribution of responses matches with the involvement of the #basalganglia-thalamo-cortical network (5/5)

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