๐ง New paper by Deistler et al: #JAXLEY: differentiable #simulation for large-scale training of detailed #biophysical #models of #NeuralDynamics.
They present a #differentiable #GPU accelerated #simulator that trains #morphologically detailed biophysical #neuron models with #GradientDescent. JAXLEY fits intracellular #voltage and #calcium data, scales to 1000s of compartments, trains biophys. #RNNs on #WorkingMemory tasks & even solves #MNIST.
๐ง New preprint by Chintaluri et al. (2025): An ion channel #omnimodel for standardized #biophysical #neuron #modelling. A unified #HodgkinHuxley formalism applied to >3,500 ion channel models from #ModelDB. Enables cross-model comparison, #clustering, and reproducible simulation through a shared parametrization:
Recently, we discussed this insightful paper by Squadrani et al (2024) in our #JournalClub. It explores how #astrocytes enhance #SynapticPlasticity during #ReversalLearning by modulating D-serine levels, providing a #biophysical basis for dynamic #LTP thresholds. The findings suggest astrocytic signaling is crucial for #AdaptiveLearning, linking #glial activity to #behavioral flexibility. Hereโs a summary from our JC:
๐ https://www.fabriziomusacchio.com/blog/2025-06-29-astrocyte_enhance_plasticity/
๐ https://doi.org/10.1038/s42003-024-06540-8
A New Tool To Characterise The Socio-Environmental Dimensions Of Urban Rivers: Urban River Socio-Environmental Index
--
https://doi.org/10.1016/j.landurbplan.2025.105388 <-- shared paper
--
#GIS #spatial #mapping #EnvironmentalEvaluation #SocioEcosystem #SocialConnectivity #UrbanRiver #Indicators #RiverRestoration #spatialanalysis #spatiotemporal #water #hydrology #urban #stream #ecosystem #cities #residents #community #nature #humanimpacts #artifical #engineered #URBS #watershed #drainage #management #restoration #geomorphology #hydrogeomorphology #ecology #urbansprawl #interdisciplinary #biophysical #social #community #France #Paris #MorbrasRiver #macroinvertebrates #riparian #vegetation #reaches #typology #landscape #landuse #landcover #variety #blandscaping
#Biophysical #principles predict #fitness of #SARS-CoV-2 #variants, Proc Natl Acad Sci USA: https://www.pnas.org/doi/abs/10.1073/pnas.2314518121?af=R
Our #study sheds light on the impact of specific #mutations on viral fitness and delivers a #tool for predicting the future epidemiological #trajectory of previously unseen or emerging low-frequency variants.
Old Forests Are Irreplaceably Cool
--
https://pubs.aip.org/physicstoday/online/43370 <-- shared technical article
--
https://doi.org/10.1038/s41561-024-01423-3 <-- shared paper
--
โSatellite measurements confirm that the sudden disappearance of mature tropical forests has a more drastic effect on local land temperature than does the gradual growth of young forestsโฆโ
#GIS #spatial #mapping #remotesensing #tropics #tropical #earthobservation #vegetation #forest #forests #loss #gain #differences #landsurface #local #temperatures #heat #coolingeffect #energybudget #biophysical #climatechange #spatialanalysis #spatiotemporal #leafareaindex #aldebo #canopy #structure #geomorphometry #NDVI #model #modeling #ecology #NASA #Aqua #Terra #satellite #atmosphere #circulation
Trees Stalling Effects Of Global Heating In Eastern US
--
https://www.theguardian.com/environment/2024/feb/17/us-east-trees-warming-hole-study-climate-crisis <-- shared media article
--
https://doi.org/10.1029/2023EF003663 <-- shared paper
--
#GIS #spatial #mapping #USA #trees #reforestation #deforestation #planting #climatechange #warming #globalwarming #spatialanalysis #spatiotemporal #colonial #history #naturalresources #forests #treeplanting #CCC #cooling #climate #benefits #biophysical #airtemperature #temperate #zones #albedo #remotesensing #earthobservation
#Road building almost always precedes #forest loss, and road density is by far the strongest correlate of #deforestation out of 38 #biophysical and #socioeconomic factors.
Findings of the study imply that the most vital #conservation function of protected areas is limiting roads and road-related environmental disruption. They suggest that burgeoning, poorly studied ghost roads are among the gravest of all direct #threats to #tropical forests.
Special #seminar this Thursday, 4/4, at noon EST with Jason George from Texas A&M. Dr. George will discuss #biophysical and stochastic modeling of the tumor-immune interaction for optimizing T cell #immunotherapies. And you can join here:
A new paper proposes a #frameworkโthe #PlanetaryCommonsโwhich differs from the global #commons framework by including not only globally shared geographic regions but also critical #biophysical systems that regulate the #resilience and state, and therefore #livability, on #Earth. The new planetary commons should create comprehensive #stewardship obligations through Earth system #governance aimed at restoring and strengthening planetary resilience and #justice.
Double #food production, save #water and at the same time increase #carbon storage - that sounds paradoxical, but would be theoretically possible, at least according to the #biophysical potential of the #earth.
#EarthScience #Environmental #sflorg
https://www.sflorg.com/2023/10/en10112301.html
In the same vein as my #arxivfeed thing, here's a paper that I've been reading and really enjoying. I decided to spend more time on it than I usually do when reading papers because I wanted to search for gaps in my knowledge, and I really don't regret that decision! I'm only at the 4th section at the moment and I find it very well written, especially in the framing of things. So far it's a great overview!
"Neural Field Models: A mathematical overview and unifying framework"
https://arxiv.org/abs/2103.10554v4
#Neuroscience #ComputationalNeuroscience #MathematicalNeuroscience #NeuralFieldModelling #Biophysical #DynamicalSystems
We used #parallelcomputing and #biophysical #simulations to go from deep, #multimodal #feature changes to #causal #differences. Result? Three conductances explained #phenotypic, #disease-related changes, an observation supported by subsequent #snRNA analysis.
Hi,
I am a #physicist and #neuroscientist who tries to bring both fields together in #neuroimaging.
I direct the Dept of Neurophysics at the #MPI for Human Cognitive and Brain Sciences (https://www.cbs.mpg.de/en). Our main tools are #MRI, #histology and #biophysical #modeling for in-vivo histology (#hMRI) and ultra-high resolution #fMRI.
Excited to see #MastodonScience growing so quickly ๐
This is my personal account and my posts/toots are just my personal views.
So we have a new #datapaper out on #biophysical & #agronomic parameters for #maize in #Ghana. This paper will be useful for folk doing #RemoteSensing #EarthObservation #CropModelling in #smallholder #agriculture systems
https://doi.org/10.5194/essd-14-5387-2022
Our next @SwanseaBioMaths Colloquium on Wed Dec 7 will be presented by @wilfred_otten on A #biophysical approach to #soil #fungal processes: from percolation theory to fungal invasion and resilience in soil systems
#biomaths #modelling
https://events.swansea.ac.uk/talk/index/2388/
Oh yes - no words on how much I missed nerding about #biochemistry and #protein #structure in all the lectures I gave the last 5 years - finally time for a special course on #biophysical #chemistry and #structural #dynamics of #proteins โฆ omg #teaching is so much easier when you bring 20y of education and expert knowledge on the topic #StructuralBiology #biophysics #teaching in #chemistry
Super busy here with preparing abstracts for today's #ISMRM conference deadline. Lots of nice results from highly interdisciplinary and collaborative projects; some foundational #MRI #physics and image reconstruction, #histology, #biophysical modeling, #qMRI, #hMRI, #diffusion MRI and layer-specific #fMRI.
In light of the ongoing #twexit I want to share our recent publication in Comms Biol here on #Mastodon
https://www.nature.com/articles/s42003-022-03997-3
A combination of #biophysical tools and #artificialinteligence helped to decode the binding affinity of multivalent peptides to their target protein gephryrin and how their architecture influences binding kinetics. Huge thx to all co-authors at Nanotemper https://nanotempertech.com/
Dynamic Biosensors https://www.dynamic-biosensors.com/
& Dominik Heiders lab! https://heiderlab.de/ ๐
Hi,
I am a #physicist and #neuroscientist who tries to bring both fields together in #neuroimaging.
I direct the Dept of Neurophysics at the #MPI for Human Cognitive and Brain Sciences (https://www.cbs.mpg.de). Our main tools are #MRI, #histology and #biophysical #modeling for in-vivo histology (#hMRI) and ultra-high resolution #fMRI.
Excited to see #MastodonScience growing so quickly ๐
This is my personal account and my posts/toots are just my personal views.
