#crystallization

John Vaccaro (johniac)johniac
2025-05-15
StructBiolCommunicationsActaCrystF@mstdn.science
2025-02-05

Crystals of His15 acetamide-modified lysozyme had similar unit-cell parameters to the unmodified tetragonal form but refinement was only possible in an orthorhombic system #AcylatedLysozyme #Crystallization #SpaceGroupAnalysis doi.org/10.1107/S2053230X25000

StructBiolCommunicationsActaCrystF@mstdn.science
2024-11-11

Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization t.co/ilB7Aa3Krg

StructuralBiologyActaCrystD@mstdn.science
2024-10-14

Three deep-learning tools, referred to collectively as CHiMP, were created for analysis of micrographs of protein crystallization experiments at the DLS synchrotron, UK. #Crystallization #ImageClassification #ObjectDetection doi.org/10.1107/S2059798324009

2024-01-09

β„οΈπŸ§Š Rime #ice (also called β€œrimfrost” in Swedish πŸ‡ΈπŸ‡ͺ) #icetodon #winter #nature #snow #weather #tuesday #photography #Crystallization

2024-01-08

πŸ§ͺπŸ”¬πŸ§Š Growing sodium chloride #salt #crystals. Here is a flat crystal, ~7.2 millimetres wide, seen with optical microscopy at 10X, 40X, 200X, and 400X. At high magnifications, we can see small crystalline domains in a highly ordered arrangement. #crystallization #science #microscopy #nature

10X40X. Bottom right corner of the 10X image.200X400X
Guillaume GaullierGuillawme@fediscience.org
2023-10-19

New paper from David Baker's lab: doi.org/10.1038/s41563-023-016
Computational design of #protein #crystals! 🀯
Spontaneous #crystallization by mixing two E. coli lysates. 🀯 🀯
Designed #protein #crystals that survive being autoclaved. 🀯 🀯 🀯

#crystallography #StructuralBiology

Same text as in the toot but in the "Vince McMahon reaction with glowing eyes" meme.
Fabio ColleFabioColleHPHT
2023-08-24

πŸ“ŒNEW PAPERπŸ“Œ

Lithos: doi.org/10.1016/j.lithos.2023.

3D reconstructions of -uCT data reveal the complex growth history of Cpx crystals. An empirical relationship estimates the βˆ†T governing the of augitic Cpx erupted at .

2023-05-01

"Garbage In, Garbage Out" - how many times have you heard this expression in structural biology?!?!

We are running a workshop on sample preparation techniques at the upcoming 2023 American Crystallographic Association meeting July 7, 2023 in Baltimore, MD - register by June 30!

acameeting.com/workshop2-sam23

#structural #SAXS #cryoem #crystallization #crystallography #lightscattering #AUC #workshop #structuralbiology

Flyer about the SAMPREP workshop at the ACA Meeting in July
getacrystal πŸ’Žgetacrystal@mstdn.science
2023-05-01

We are excited to announce the Meritorious Users Program at the National Crystallization Center! Are you a structural biologist at a US PUI or MSI? Is your laboratory under-resourced? Take a look at the program for HT πŸ’Ž screening! We screen 1536 conditions in one experimental plate! Application deadline May 31 for the 1st round of screening!
#crystallization #structuralbiology #crystallography #research #access
getacrystal.org

Flyer describing the Meritorious Users Program at the National Crystallization Center www.getacrystal.org
getacrystal πŸ’Žgetacrystal@mstdn.science
2023-04-25

It's time to see... How HWI is providing scientists with models created to design drugs, vaccines and other treatments for diseases.

youtube.com/watch?v=_Xo8E5Wqv0

www.getacrystal.org

#structuralbiology #crystallization #crystallography

HWI National Crystallization Center highlight
2023-04-15

🌸 #Flower power – #calcium sulphate #crystals come in all shapes and forms! πŸ’ŽπŸ”¬πŸ”ŽπŸ¦΄

#microscopy #electronmicroscopy #imaging #photography #biomineralization #biomaterials #sulphur #sulfur #crystallization #nature

Flower-like calcium sulphate crystals formed spontaneously on the surface of a bone sample after being exposed to tryptic soy broth. Staphylococcus aureus is also cultured on the sample – but that is irrespective. Imaged using scanning electron microscopy.
getacrystal πŸ’Žgetacrystal@mstdn.science
2023-04-04

Happy to share this new video about @getacrystal operations: lnkd.in/eT6MUP6i
@XtalMaker, @gabbybudz, @MirandaLynchPhD, @mumstheword, Tiffany Wright, Eddie Snell, Steve Potter
#structuralbiology #crystallization #crystallography

Link to video highlighting National High-Throughput Crystallization Center operations at HWI.
2023-03-18

Excited to be presenting a Thermo Fisher Scientific Ask the Experts webinar 3/22/23 11am EDT with Devrim Acehan!

We'll discuss emerging methods in cryo-EM of microcrystals, as well as our collaborative work as we seek to further develop microcrystal detection and handling methods.

Register here: tinyurl.com/2p9d9zer

www.getacrystal.org
www.cryo-EM.center

#structuralbiology #crystallization #cryoem #microED #webinar
@strucbio

Thermo Fisher Scientific webinar announcement: Leveraging the integration of cryo-EM and X-ray based methods for a comprehensive approach to structural biology
Max Planck Institute MagdeburgMPI_Magdeburg@social.mpdl.mpg.de
2023-03-15

πŸ“£Andreas Seidel-Morgenstern has been elected as a member of the National Academy of Engineering of the USA for his contributions to #adsorption, #chromatography, #crystallization processes, and the separation of #enantiomer mixtures - congratulations!

mpi-magdeburg.mpg.de/4385805/2

Portrait of Andreas Seidel-Morgenstern. Β© Stefan Deutsch / Max Planck Institute Magdeburg
2023-03-04

Happy to share our recent paper on high-throughput crystallization in the HTX Center is out in Acta D!
'20 years of crystal hits': scripts.iucr.org/cgi-bin/paper

Stay tuned for more!!

@getacrystal
@MirandaLynchPhD @mumstheword
@structbio

#research #structuralbiology #crystallization #crystallography #xray #access

Image showing the HT 1536 crystallization screen in the background, with zoomed in images of individual wells with positive crystal hits (brightfield, UV-TPEG, & SHG imaging).
2022-12-13

Our paper on immiscible #polyolefin blends is out! Here we check out the effects of polyethylene-polypropylene blend composition on #crystallization and melting - morphology plays a huge role in the rheological properties during crystallization as well as the #crystallization temperature of the blend components: pubs.acs.org/doi/full/10.1021/ #rheology #raman #dsc

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