#epigenetic

David Ojciusojcius
2026-02-23

Microbial SCFAs as mediators: fine-tuning the gut-brain axis in disorders.

Short-chain fatty acids from gut microbes modulate brain epigenetics, offering neuroprotective effects & therapeutic potential for neurodegenerative disorders.

davidojcius.blogspot.com/2026/

Short-chain fatty acids from gut microbes modulate brain epigenetics, offering neuroprotective effects & therapeutic potential for neurodegenerative disorders.
2026-02-05

In this Commentary, Zhang et al. discuss the novel strategy developed by Chen et al. that improves drought tolerance in #rice, by connecting rhizosphere #ecology, gaseous signaling, and #epigenetic control.
doi.org/10.1111/jipb.70104
@WileyLifeSci
#PlantSci #CropSci #agriculture #JIPB

chris@strafpla.netchris@strafpla.net
2025-12-30

Weirdest question we came up with at #39c3:
If #Chemotherapy quite frequently changes hair color, is this an indicator that hair color is in part defined by an #epigenetic mechanism? Will there be pills to change hair color in the future? I’ll need to ask one of the friends who have students explore strange stuff about this…

MPI Immunbiologie & Epigenetikmpi_ie
2025-12-15

Our PhD program IMPRS-EBM looks for applications. 📢

Want to work at the forefront of epigenetic research at a MPI? Looking for a fully-funded at Max Planck?

We invite you to go on a scientific journey with us at the forefront of epigenetic research. Our MPI-IE & @unifreiburg faculty are committed to understanding **#epigenetic** mechanisms from a molecular biology perspective, complemented by the lenses of **#metabolism** & **#biophysics**.

ie-freiburg.mpg.de/IMPRS-PhD-P

Timeline infographic showing PhD application process from Dec 15 online application opening to Sept 2026 program start, with key dates for interviews and deadlines.
2025-12-10

This global profiling of lysine-malonylated #proteins in #rice leaf sheaths, and the changes in these proteins under biotic stresses, reveals #epigenetic mechanisms for developing #crops with broad-spectrum stress #resistance.
doi.org/10.1111/jipb.70050
@WileyLifeSci
#PlantSci #JIPB #botany

Proposed mechanism by which lysine malonylation enhances rice resistance to herbivores/viruses via metabolic/chromatin modulation, with the histone deacetylase OsHDA711 as a negative regulator. Additional panels illustrate data and morphological results supporting these findings.
2025-11-25

1/ This Review Article in our new Focus Issue outlines how #epigenetic and metabolic rewiring enables innate immune cells to ‘remember’ past challenges, shaping protection, pathology, and new therapeutic strategies.
elifesciences.org/articles/108

Triggers of trained immunity across all tissues.
Scientific Frontlinesflorg
2025-10-09

Complex changes in regulation driven by mechanisms. The results demonstrate how environmental contribute to the development of resistance and metabolic .

sflorg.com/2025/10/eco10092501

2025-08-28

Great talk by Guy Ron at the #MCBIM mini-symposium at Leiden University.

He talked about multiplexed, single-molecule methods to detect #epigenetic modifications that are important in #cancer and can be used for #diagnosis.

nature.com/articles/s41587-022

#Chemistry #ChemBio #DrugDiscovery

Great talk by Guy Ron at the #MCBIM mini-symposium at @leidenscience.bsky.social. He talked about multiplexed, single-molecule methods to detect #epigenetic modifications that are important in #cancer and can be used for #diagnosis. www.nature.com/articles/s41... #ChemSky #ChemBio #DrugDiscovery

2025-08-08

#Fire alters the #phenotype of individual #plants, potentially through #epigenetic mechanisms

New paper:
Phenotypic rebuilding after fire: Understanding within-individual variability in a Mediterranean shrub besjournals.onlinelibrary.wile
By Saiz-Blanco, @cmhmaliani et al @JEcology

@ecology @plants @botany @wildfirescience @plantscience @nature @epigenetics @biodiversity @evolution @ecologies #fireecology #resprouting

Architectural change produced by post-fire resprouting in Anthyllis cytisoides. Undisturbed individuals (a) usually have a single-stem, apical dominant structure. Individuals resprouting post-fire (b) have a multi-stem structure without apical dominance.
2025-08-02

Photoperiod sensitivity affects #flowering time and, ultimately, #yield. Wang et al. reveal new insights into how the LUX-SWI3C module regulates #photoperiod sensitivity in #Arabidopsis at the #epigenetic level.
doi.org/10.1111/jipb.13889
@wileyplantsci
#PlantSci #JIPB #botany

Proposed model for the LUX and SWI3C regulation of photoperiod sensitivity in LD WT, SD WT, and LD/SD lux swi3c mutant plants.
2025-07-27

Gibt es Studien zum Einfluss des Patriarchats auf die Epigenetik des Menschen?

#wildeThese

#Epigenetik #epigenetic #Patriarchat #studie

2025-07-17

Can #AI and #ML help integrate and analyze #epigenetic data of plant stress responses to optimize the training of the parent #plants?
Dobránszki et al. explore the possibilities in this fascinating #JIPB review!
doi.org/10.1111/jipb.13953
@wileyplantsci
#PlantSci #botany #OpenAccess

This diagram illustrates how artificial intelligence and machine learning can predict plant behavior in response to environmental stress by modeling molecular regulatory networks of plant stress responses.
Daniel Hoffmann 🌼Daniel_Hoffmann@mathstodon.xyz
2025-06-27

Gene expression is tuned by #epigenetic changes, which explains why, say, liver and skin cells have the same genome but are otherwise different. Here we introduce a
#Bayesian model for the analysis of epigenetic changes during development. epigeneticsandchromatin.biomed

2025-06-13

Epigenetic regulators like EZH2 are mutated in #Bcell #lymphoma, but what is their effect? This study reveals a role for mutant EZH2 in lymphomagenesis, using a new method for measuring #epigenetic heterogeneity & intra- #chromatin connectivity in #cancer @PLOSBiology plos.io/4mZcS8n

EZH2-mutants exhibit two distinct epigenetic populations. Top: Joint UMAP of OCI-Ly7 WT cells and the isogenic EZH2 Y646N cells (Left) or dMUT cells (Right). Colors indicate the sample index. Bottom: Only mutant-EZH2 cells are plotted, to highlight the subpopulation of mutant cells that cluster with WT cells, referred to as ‘WT-like’. The subpopulation of cells that cluster separately from WT is referred to as EZH2 Y646N ‘extreme’ or dMUT ‘extreme’, respectively.
Matteo Cesarimacesari
2025-06-10

A blood-based clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and factors

"...a validated tool bridging molecular readouts of and clinical assessments of ..."

nature.com/articles/s43587-025

Yliopistobottiyliopistobotti
2025-05-19

Dr Juha Kere from @ki.se was our key note speaker for
the day. He gave an excellent talk about GWAS studies and programming. What a start for our seminar!

bsky.app/profile/inflames-flag

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