Lmst

#Fungal infections are hard to treat due to #DrugResistance. @blake_billmyre &co use a high-throughput #TNseq system in #Cryptococcus neoformans to identify >1400 essential genes & reveal a role for #mitochondrial genes in #fluconazole sensitivity @PLOSBiology https://plos.io/4dz3iVm

Schematic of TN-seq in C. neoformans. Top left: Transposon insertions (orange arrow) into nonessential genes results in viable cells. In contrast, insertions into essential genes will result in dead and nonrecoverable cells. Top right: TN-seq works by generating a library of cells where each cell has a single independent transposon insertion in a random location. As in A, those insertions into essential regions cause the cells to die and are nonrecoverable. As a result, the total library (bottom) is depleted in insertions in essential regions. Bottom: The Ac/Ds transposon was split into an Ac transposase and a Ds transposon containing a neomycin resistance marker. This Ds transposon was integrated into an intron of URA5 and the Ac transposase was integrated into the safe haven locus. The resulting stain is ura− and neomycin resistant. Upon initiating transposition via growth on galactose, the strain becomes URA+ and mutant at another locus (depicted here as YFG1).

New entry of AI-generated #comics and #jokes added to our #website:

#Fungal #Forecast

comics.lucentinian.com/7935
#AILaughs #DailyComedy #Laughs #VisitNow #NewsLaughs

🍄 #Fungal infection with a systemic impact: #Aspergillus affects not just the lungs 🫁 but also the gut and metabolism. A new study from Jena shows the #microbiome is key.

#BalanceOfTheMicroverse @unijena #UniklinikJena
@dfg_public @bmftr_bund

👉 press release
https://shorturl.at/XTuPd

👉 DOI: https://lnkd.in/ddv3RJsw

The growth of 𝘓𝘪𝘨𝘪𝘭𝘢𝘤𝘵𝘰𝘣𝘢𝘤𝘪𝘭𝘭𝘶𝘴 𝘮𝘶𝘳𝘪𝘯𝘶𝘴 (orange), a member of the murine lung microbiome, along the hyphae of the lung-pathogenic fungus 𝘈𝘴𝘱𝘦𝘳𝘨𝘪𝘭𝘭𝘶𝘴 𝘧𝘶𝘮𝘪𝘨𝘢𝘵𝘶𝘴 (blue), with lung tissue in the background.

#Lichens are symbionts. There is a #fungal component (most are about 90 percent fungus) and a photosynthetic component (#algae or #cyanobacteria). Whether lichens can survive on #Mars 🔴 depends on the species. https://arstechnica.com/science/2025/04/lichens-can-survive-almost-anything-and-some-might-survive-mars

Pretty cool that more and more information is spreading about #fungal #networks! Here a link from National Geographic on impressive work some colleagues did on mycorrhizal networks https://www.nationalgeographic.com/science/article/fungi-underground-mycelium-network-plants-the-last-of-us

Man Develops #Fungal #Lung #Infection Due to #Dirty #Sock #Smelling #Habit

https://www.odditycentral.com/news/man-develops-fungal-lung-infection-due-to-dirty-sock-smelling-habit.html

Common #Fungal Compound May Be the Key to Fighting Deadly #Flu Infections

https://scitechdaily.com/common-fungal-compound-may-be-the-key-to-fighting-deadly-flu-infections/

Spray-induced #gene silencing is an innovative, #EcoFriendly technology for controlling #plant #fungal diseases by applying #RNA molecules that silence key fungal genes via RNA interference.
Learn more in this new guide!
https://doi.org/10.1111/jipb.13848
@wileyplantsci
#PlantSci #JIPB #botany

Image of a whole-leaf section of a plant, with some leaves in pale green with dark spots indicating fungal infection. The text next to the image reads "Spray-Induced Gene Silencing (SIGS)."

A blueprint for making #cereal #crops more resistant to #fungal #disease.

#agriculture #immune #receptor #MLA13 #AVRA13-1 #powdery_mildew

https://phys.org/news/2025-02-blueprint-cereal-crops-resistant-fungal.html

Forest species in a climatic transition zone absorb phosphorus through root enzymes or fungal partners, ensuring resource use and coexistence.👍
#forest #fungal
@Forestecosystems
https://www.sciencedirect.com/science/article/pii/S2197562023000428

Overall, we hope this work demonstrates that a Mucorales-specific biomarker can be used to identify invasive #mucormycosis. Long term, we hope that this work will support efforts to improve patient outcomes for this devestating invasive #fungal disease. 12/

Check out the paper for more gorgeous #fungal #bioimaging from this team of women clinician scientists. Congratulations again to @AlyssaHudson83 and @forestcita. A big thank you to @NoahsPinkB Leukaemia Fund for supporting Alyssa's training. https://bit.ly/4eG3lyz

#Mucormycosis is a devastating #invasive #fungal disease affecting immunocompromised people and is acquired from the environment. Early and accurate diagnosis is essential, as untreated this fungus rapily invades and destroys tissue. Infection is life altering and deadly. 2/

#Agarwood is a nontimber #forest product with high #economic and #medicinal value. Using a polyphasic approach, Du et al. reveal 10 novel and 1 known saprobic #fungal #taxa from terrestrial agarwood-producing #trees. https://doi.org/10.1111/jse.13128
@WileyEcolEvol
#JSE #ecology #evolution #botany

Diagram describing saprobic fungi associated with two native Chinese agarwood-producing tree species (Aquilaria sinensis and A. yunnanensis) in Guangdong and Yunnan provinces, China. Based on morphological characteristics, multigene phylogenetic analyses, and pairwise homoplasy index (PHI) test, 10 collections are introduced as one new genus – Aquilariomyces, nine new species – Aquilariomyces aquilariae, Corynespora aquilariae, Melomastia maomingensis, Nigrograna aquilariae, Parathyridariella aquilariae, Peroneutypa maomingensis, Phaeoseptum aquilariae, Pseudothyridariella aquilariae, and Triangularia aquilariae, and one known species – Camarographium clematidis, belonging to different families of Ascomycota, namely, Corynesporascaceae, Diatrypaceae, Didymosphaeriaceae, Nigrogranaceae, Phaeoseptaceae, Pleurotremataceae, Podosporaceae, and Thyridariaceae.

Zajímají vás houby a jejich ekologický význam?😮

🖥️Připojte se 24. 9. 2024 na speciální díl SciStarter LIVE a objevte projekt #FunDiS – dokumentování #fungal diversity v Severní Americe!🍄🌎

Více info a registrace na: http://scistarter.org/go/LIVE

#citizenscience #obcanskaveda

Big Friday news from SYLVA! In mid-August, our project partner Helmut Hund GmbH installed the Northern-Pilot Pollen Monitor POMO® BAA500 in the heart of the Pallas Yllästunturi National Park in 🇫🇮 , as part of the @SYLVAbioaerosol project.

They also reported that #fungal spores were sampled right after the POMO® BAA500 was set into operation at the Pallas station! 🎉

#allergy #bioaerosol #horizoneurope #EUgreenresearch

Photos: Helmut Hund GmbH

A 6 months internship (M2) is open in our laboratory for January 2025 to work on #RNA, the genetics and biochemistry of its #splicing, export from the nucleus and degradation in the cytoplasm. With new tools and exciting preliminary results in #Cryptococcus neoformans, an intron-rich and fascinating human #fungal pathogen.

https://cosminribo.eu/posts/2024-07-m2topic/

#Fungal #resistance in #plants associated with heritable differences in #microbiota abundances.

#Sclerotinia #rhizosphere #microbiome #genomic

https://phys.org/news/2024-05-fungal-resistance-heritable-differences-microbiota.html

Report: Global #wine production worst in 62 years due to 'extreme #climate events'

The 10% decrease is the world's steepest drop in wine production in 62 years, according to the industry report. The #grape harvest was the worst reported since 1961.

By Mike Heuer, UPI

Published Apr 29, 2024

"#Fires, #droughts and other conditions commonly associated with a changing global climate greatly contributed to making the world's 2023 wine production the worst in 62 years, industry officials have reported.

"A 'State of the World Vine and Wine Sector in 2023' report released Thursday by the France-based International Organization of Vine and Wine cites 'extreme environmental conditions' as a primary cause of a 10% drop in global wine production in 2023.

"John Barker, director of the wine organization, said 'drought, #ExtremeHeat and fires, as well as #HeavyRain causing #flooding and #fungal disease across major northern and southern hemisphere wine production regions" were primary factors in the decrease in global wine production.

"The 10% decrease is the world's steepest drop in wine production in 62 years, according to the industry report. The grape harvest was the worst reported since 1961.

"A 26% drop in wine production in #Australia and a 23% drop in #Italy made those nations the worst in 2023. #Spain lost more than 20% of its wine production, and #Chile and #SouthAfrica each recorded 10% drops."

https://www.accuweather.com/en/climate/report-global-wine-production-worst-in-62-years-due-to-extreme-climate-events/1645758

#ClimateChange #ClimateCrisis #FoodShortages #HungerGames

Scientists map #soil #RNA to #fungal #genomes to understand #forest ecosystems.

#microbiome #Metatranscriptomics

https://phys.org/news/2024-04-scientists-soil-rna-fungal-genomes.html

#fungal

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