Lmst

Ovarian multinucleated giant cells are a #macrophage population in the #aging mammalian #ovary. This study reveals a potential role in degradation of cellular debris & #immune signaling, suggesting a contribution to ovarian #inflammation during aging @PLOSBiology https://plos.io/3T84WE0

Multinucleated giant cells (MNGCs) are age-associated in mammalian ovaries. Top and middle panels show representative mouse and nonhuman primate (NHP) ovarian histological sections (from left: 6-12-week mice, 9-month mice, 12-month mice, 15-month mice, 13-year rhesus macaque. Bottom panels show trainable Weka Segmentation (ImageJ) of MNGCs across age.

Neonatal fungi: lifelong metabolic health via macrophage β cell development

https://www.science.org/doi/10.1126/science.adn0953

#HackerNews #NeonatalFungi #MetabolicHealth #Macrophage #βCellDevelopment #ScienceResearch #HealthScience

PhD position - Cardiovascular/Cardiometabolic Immunology

Ludwig Maximilians University Hospital

See the full job description on jobRxiv: https://jobrxiv.org/job/ludwig-maximilians-university-hospital-27778-phd-position-cardiovascular-cardiometabolic-immunology-2/?feed_id=82599

#flow_cytometry #Heart #macrophage #metabolism #RNAseq #ScienceJobs #hirin...
https://jobrxiv.org/job/ludwig-maximilians-university-hospital-27778-phd-position-cardiovascular-cardiometabolic-immunology-2/?feed_id=82599

PhD position - Cardiovascular/Cardiometabolic Immunology

Ludwig Maximilians University Hospital

See the full job description on jobRxiv: https://jobrxiv.org/job/ludwig-maximilians-university-hospital-27778-phd-position-cardiovascular-cardiometabolic-immunology-2/?feed_id=82529

#flow_cytometry #Heart #macrophage #metabolism #RNAseq #ScienceJobs #hirin...
https://jobrxiv.org/job/ludwig-maximilians-university-hospital-27778-phd-position-cardiovascular-cardiometabolic-immunology-2/?feed_id=82529

https://www.bbc.com/news/articles/c1wwdd6v2wjo “The group of researchers at the Francis Crick Institute and University College London performed a deep genetic analysis to try to unpick the cause of the #IBD.
They discovered a section of genetic code – or #DNA – that turns out to be the #macrophage’s “master regulator” of #inflammation.
It sits right at “the top of the pyramid” says Dr James Lee, from the Francis Crick Institute. (1/2)

PhD

Justus Liebig University Giessen Germany

Interested in specializing in macrophage biology and utilizing cutting-edge technologies? Apply now for this PhD opportunity.

See the full job description on jobRxiv: https://jobrxiv.org/job/justus-liebig-university-giessen-germany-27778-phd/?feed_id=75704

#bioinformatics #codex #flow_cytometry #macrophage #scrna_seq #ScienceJobs #hiring #research
https://jobrxiv.org/job/justus-liebig-university-giessen-germany-27778-phd/?feed_id=75704

PhD

Justus Liebig University Giessen Germany

Interested in specializing in macrophage biology and utilizing cutting-edge technologies? Apply now for this PhD opportunity.

See the full job description on jobRxiv: https://jobrxiv.org/job/justus-liebig-university-giessen-germany-27778-phd/?feed_id=75459

#bioinformatics #codex #flow_cytometry #macrophage #scrna_seq #ScienceJobs #hiring #research
https://jobrxiv.org/job/justus-liebig-university-giessen-germany-27778-phd/?feed_id=75459

https://nkvssp.thecomicseries.com/comics/433

Cells at Work!

#puppy #kitteh #ralph #healthcare #cartoon #fridaymorning #webcomics #webcomicchat #comicbookhour #comics #NKVSSP #manga #CellsAtWork #educational #fun #FridayReads #recommended #redBloodCell #platelet #Macrophage #immune #FridayVibes #vibecheck

Studying #Salmonella infection and #macrophage interactions in zebrafish embryos. #Microbiology https://elifesciences.org/articles/89828?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Postdoc in the Cardiovascular Research Institute, at UCSF (Fidler Lab)

UCSF

The Fidler lab at UCSF is recruiting postdoctoral scientists to lead research projects centered on atherosclerosis and thrombosis.

See the full job description on jobRxiv: https://jobrxiv.org/job/ucsf-27778-postdoctoral-scientist/?feed_id=71245

#atherosclerosis #cardiovascular #Clonal_Hematopoiesis #crispr #hematopoiesis #Macrophage #Scienc...
https://jobrxiv.org/job/ucsf-27778-postdoctoral-scientist/?feed_id=71245

#science #macrophage #immunecell

Macrophage in action vs E. coli: MOA Animation of Phagocytosis, a fundamental immunological process

https://www.youtube.com/watch?v=X_T4m3iA5WA

#science #macrophage #immunecell

Macrophage in action vs E. coli: MOA Animation of Phagocytosis, a fundamental immunological process

https://www.youtube.com/watch?v=X_T4m3iA5WA

#science #macrophage #immunecell

Macrophage in action vs E. coli: MOA Animation of Phagocytosis, a fundamental immunological process

https://www.youtube.com/watch?v=X_T4m3iA5WA

Postdoc in the Cardiovascular Research Institute, at UCSF (Fidler Lab)

UCSF

The Fidler lab at UCSF is recruiting postdoctoral scientists to lead research projects centered on atherosclerosis and thrombosis.

See the full job description on jobRxiv: https://jobrxiv.org/job/ucsf-27778-postdoctoral-scientist/?feed_id=69858

#atherosclerosis #cardiovascular #Clonal_Hematopoiesis #crispr #hematopoiesis #Macrophage #Scienc...
https://jobrxiv.org/job/ucsf-27778-postdoctoral-scientist/?feed_id=69858

"Backpacks durably adhered to the surface of macrophages without internalization & maintained an anti-inflammatory phenotype of the carrier macrophage through 7 days in vitro. Backpack-macrophage therapy was scaled up & safely infused into piglets in a cortical impact Traumatic brain injury (TBI) model..The results..demonstrate..the first use of a cell therapy intervention for a large animal model of #TBI & highlight the potential of #macrophage-based #therapy"

https://academic.oup.com/pnasnexus/advance-article/doi/10.1093/pnasnexus/pgad434/7471889?login=false

Attending #SETACLouisville and interested in #PFAS and the #immune system? You’re in luck! 🧵

My virtual talk on how PFAS impact #macrophage function is available to view now! Just search for my name or “1.05.V-030” on the meeting platform.

#SETAC
1/3

Obesity confers #macrophage memory

◽️Obesity triggers #epigenetic reprogramming of the innate immunity, lasting long after return to normal weight

◽️Stearic fatty acid (via TLR4) remodels chromatin & ↑AP-1 accessibility

◽️MΦ shift OXPHOS→ glycolysis

https://science.org/doi/10.1126/science.abj8894

#Macrophage-derived #insulin antagonist ImpL2 causes #lipoprotein mobilization upon bacterial #infection
Adam Bajgar, Tomas Dolezal and coworkers, University of South Bohemia
https://www.embopress.org/doi/full/10.15252/embj.2023114086

Research with lab mice shows an experimental vaccine stimulates the body's basic immune system to protect against a range of pathogens associated with hospital infections.

https://sciencebusiness.technewslit.com/?p=45295

#News #Press #Science #Business #Biotechnology #Chemistry #Infections #Hospital #Superbugs #Macrophage #Bacteria #Fungi #MRSA #Preclinical #Licensing #IntellectualProperty #University

'LPS induced a sustained increase in IFNγ levels and unresolvable inflammatory lung injury in the mice lacking RGS2 but not in RGS2 null chimeric mice receiving WT bone marrow or receiving the RGS2 gene in alveolar #macrophage.'

#Preprint #immunology

https://www.biorxiv.org/content/10.1101/2023.09.22.559016v1

#macrophage

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