Gabrielle is giving a talk today in the Warwick SLS-WMS Postdoc Association Seminar Series.
"Hacking the logic of clathrin-coated vesicle creation”
10 am in A1.51, Gibbet Hill
#membranetraffic
A riddle for Golgi Day: how many Golgis can you spot in this photo? #membranetraffic #CellBiology
I’m currently looking for a post-doc in the UK, particularly to work on projects that employ in-vitro reconstitution and quantitative #microscopy approaches to study #cellbiology processes (esspecially #membranetraffic) + would be grateful for sign-posting towards openings! 🙏 #academicchatter
We received this payment card protector to incentivise us to take part in an Office for National Statistics Crime survey.
I said, ‘ah they’ve used the classic Biorender concentric-ring endoplasmic reticulum icon as their logo.’
My partner responded, ‘I think that’s meant to be a finger print because it talks about protecting your identity.’
Only the real ones would understand… #CellBiology #membranetraffic
EMBO Workshop
From molecules to organisms: An integrative view of cell biology
16 – 21 March 2025 | Radstadt, Austria
Organised by Sharon Tooze and Marino Zerial
Deadline is 1st Dec
https://meetings.embo.org/event/25-cell-bio
And now for some new News!
This week we welcomed Anneline Moret to our lab. Anneline is a EUTOPIA co-tutelle student between our lab and Paris Cergy University. She'll be working on engineered membrane traffic of integrin in a cancer context.
In September, Mary's paper on ATG9A-flavour INVs was posted on bioRxiv.
ATG9 vesicles are a subtype of intracellular nanovesicle
This was a highlight from the UK Membrane Traffic meeting last year. Looks like there is some new analysis in here compared to the preprint.
Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes
As I’m writing an overview of membrane trafficking mechanisms for my PhD thesis introduction, I’m remembering Prof David Stephens (1971-2024) and Dr Ian Moore (1964-2018) and how they shaped my thinking and nurtured my enthusiasm through conversations that have stuck with me for many years or comprehensive and captivatingly written reviews. I’m sure countless other scientists can say the same. Both were gone too soon, but their legacy will continue to inspire us #CellBiology #MembraneTraffic
As I ponder the molecular anatomy of the trafficking organelles I’ve been working on during my PhD in the final stretch of my thesis writing, I remain in awe of this tour-de-force of a paper that tackled this question nearly 20 years ago. Takamori et al., Cell (2006): https://www.cell.com/cell/fulltext/S0092-8674(06)01400-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867406014000%3Fshowall%3Dtrue
The v-ATPases visibly poking out of the vesicle membranes in their electron tomograms look so cute - they’re my all-time favourite proteins!
This is an interesting paper from Min Lui and Alan Jian Zhu about EHPB1 inhibiting the clathrin adaptor protein1 (AP1) to ensure wingless is delivered to both the apical and basolateral surfaces.
https://www.embopress.org/doi/full/10.1038/s44319-024-00289-1
Deeply saddened by the news that my friend David Stephens died last night.
David was an outstanding cell biologist based at Bristol whose work spanned #MembraneTraffic #cytoskeleton #ciliogenesis and more. He was “one of the good guys”. Kind, supportive, generous with his time, and rigorous about his science. I’ll miss him.
Gabrielle is giving today's @Warwick_CMCB talk at 13.05 in T0.08/09
“Hacking the logic of clathrin-coated vesicle formation”
UK #MembraneTraffic people: this year's meeting is organised by Jez Carlton and Chris Stefan. It'll be at KCL (Guy's) 16th Dec.
There's a call for talks and sign up. If you're interested but not on the email list, HMU.
Just a note of appreciation for this review of phosphoinositide signalling in membrane trafficking from Volker Haucke’s lab: https://www.nature.com/articles/s41580-022-00490-x
It’s so comprehensive + the graphics are beautiful. I’ve regularly referred to it over the last couple of years to find the primary literature references I was after and every time I open the PDF I still go, ‘wow, that’s amazing!’ #CellBiology #membranetraffic #thesiswriting #PhDlife
Hooray for #MembraneTraffic #CellBiology
Scott Emr and Wesley Sundquist Awarded 2024 Horwitz Prize for Discovering the ESCRT Pathway
Seeing these vesicles zooming around the cell + then darting over to the mitochondria within seconds after you add the drug to trap them there never gets old 🔬🤩 #CellBiology #microscopy #membranetraffic #BiologyIsBeautiful
From: @steveroyle
https://biologists.social/@steveroyle/113125154969359577
We have a new preprint out!
It's about the molecularly diverse world of Intracellular Nanovesicles (INVs).
ATG9 vesicles are a subtype of intracellular nanovesicle
https://www.biorxiv.org/content/10.1101/2024.09.12.612637v1
@MAFesenko @Moore_cell Peyton Ewbank
@roylelab @Warwick_CMCB
I was in Cambridge yesterday to do a PhD viva of Jessica Eden, the first PhD from the lab of David Gershlick at CIMR. For anyone interested, her main thesis paper is up on bioRxiv investigating RABGAP1 in trafficking and processing of APP (amyloid precursor protein).
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