Increasing internal pressure in certain tumors pushes a button (a molecular cascade) in #tumor cells that switches them to a #metastatic escape mode. Knowing this mechanical switch could help to design new treatments.
https://elifesciences.org/reviewed-preprints/100490
#metastatic
Putting the t1000e #metastatic tracker in CLIENT_HIDDEN mode since it doesn't seem to be able to get picked up by the rest of the local mesh. Good reminder that the network is always listening and you shouldn't be broadcasting your GPS on open comms.
I don't think I'd recommend this affordable tracker to beginners unless you just want to kind of listen in to understand what's going on in your local mesh.
It's been a while since my previous instance got shafted by spammers and started being defederated & blocked, and then the one I was going to move to also took a nosedive in uptime terms.
So here I am again.
I still have advanced #metastatic #prostate #cancer but since then it transpires that #SirChrisHoy has selfishly announced that he, too, has the same one except his is slightly more advanced than mine, because of course it is (this is of course ever so slightly light-hearted).
Andrew M. Lewis, Jr & Gladys S. Lewis on #PLOSONE October 24, 2022
The AGMK1-9T7 cell model of #neoplasia: Evolution of #DNA copy-number aberrations and #miRNA expression during transition from normal to #metastatic #cancer cells
B.C. research: New blood test could 'transform' cancer treatment | CTV News https://bc.ctvnews.ca/new-blood-test-could-transform-cancer-treatment-b-c-research-1.6006877 https://bc.ctvnews.ca/mobile/new-blood-test-could-transform-cancer-treatment-b-c-research-1.6006877?cache=yesclipId10406200text/html;charset=utf-80404/7.263352 “researchers at #BCCancer and the Vancouver #Prostate Centre said they've developed a new blood test that provides "unprecedented" insight into a patient's cancer make-up.
"analyzes the DNA that #metastatic #cancers shed into the bloodstream, known as circulating tumour DNA or #ctDNA,"
helps to reveal characteristics that are unique to each patient's cancer, “
Plant Virus Fights Cancers in Mice With 'Widespread Effectiveness'
https://www.sciencealert.com/plant-virus-fights-cancers-in-mice-with-widespread-effectiveness #medicine #metastatic #cancer #plant #virus #cowpea #mosaic
Forget lung, breast or prostate cancer: why tumour naming needs to change
https://www.nature.com/articles/d41586-024-00216-3 #cancer #tumour #metastatic#organ #oncology #treatment #nomenclature #classification
Andrew M. Lewis, Jr & Gladys S. Lewis on #PLOSONE October 24, 2022
The AGMK1-9T7 cell model of #neoplasia: Evolution of #DNA copy-number aberrations and #miRNA expression during transition from normal to #metastatic #cancer cells
The overall 5-year survival rate for primary #bonecancers stands at 76-79%, with higher rates for localized cases. #Metastatic #bonecancer, originating elsewhere, exhibits a poor #prognosis.
https://indianf.com/unlocking-mysteries-bone-cancer/#:~:text=The%20overall%205%2Dyear%20survival%20rate%20for%20primary%20bone%20cancers%20stands%20at%2076%2D79%25%2C%20with%20higher%20rates%20for%20localized%20cases.%20Metastatic%20bonecancer%2C%20originating%20elsewhere%2C%20exhibits%20a%20poor%20prognosis.
Exercise
Reduces pain,
Decreases fatigue.
Hope for metastatic breast cancer
Patients.
#exercise #breastcancer #metastatic #pain #fatigue #cinquain #poetry
This collection of gifts is for all those with a cancer diagnosis, including those with #metastatic, stage 4 disease. http://dlvr.it/Sx7wSw
Educational Review: The different faces of #metastatic #melanoma in the #gastrointestinal tract. (Eva Mendes Serrao et al.)
Click here to read the full article ➡️ https://insightsimaging.springeropen.com/articles/10.1186/s13244-022-01294-5
“Paradoxical” – Metastatic Breast Cancer’s Trojan Horse
Lymph nodes act as one of the body’s first lines of defense against disease. From these organic control centers, immune cells are sent into battle against foreign invaders. But somehow, lymph nodes are also the first stop for most metastatic cancers.
https://scitechdaily.com/paradoxical-metastatic-breast-cancers-trojan-horse/ #BreastCancer #metastatic #LymphNodes #ImmuneCells
A Teenage Girl Refuses More Cancer Treatment; Her Father Disagrees
Tough Decisions From My Ethics Caseload
There was a very interesting case recently involving a young woman I'm going to call Tinslee. She was 17 years old and she suffered, sadly, from recurrent metastatic osteogenic sarcoma. She had bone cancer. It had first been diagnosed at the age of 9. She had received chemotherapy and been under that treatment for a while.
https://www.medscape.com/viewarticle/991956?src=rss
#BoneCancer #recurrent #metastatic #osteogenic #sarcoma #chemotherapy #minor #parent
NALCN-mediated sodium influx confers #metastatic #prostatecancer cell invasiveness
Natalia Prevarskaya and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2022112198
What determines #metastatic colonization of distant organs?
Momo Bentires and colleagues identify an epigenetic axis of #NNMT, #PPRDM5, and #collagen expression in promoting plasticity and extracellular matrix remodeling in aggressive basal-like breast cancer
https://www.embopress.org/doi/10.15252/embj.2022112559
New Weapon Against Brain Cancer: Gene Engineered Cell Therapy’s Two-Pronged Assault on Metastatic Melanomas
Brigham and Women’s Hospital researchers have developed a ‘twin stem cell model’ therapy to treat melanoma brain metastases. One stem cell releases a tumor-attacking virus while the other, genetically modified to resist the virus, strengthens the immune system. This locally delivered therapy, successful in preclinical mouse models, holds promise for future clinical trials.
https://scitechdaily.com/new-weapon-against-brain-cancer-gene-engineered-cell-therapys-two-pronged-assault-on-metastatic-melanomas/ 3BrainCancer #treatment #metastatic #melanoma
Yesterday, in the afternoon plenty of #scRNAseq work, a.o. Céline Delloye-Bourgeois showing her group's latest work on #neuroblastoma development and #metastatic progression. Including some of our own scRNA-seq data. Very cool.
Furthermore, more #SingleCell, also spatial, sequencing on #tumour heterogeneity and early stages. And work on cells that persist during/after #therapy, dubbed persister cells.
Postdoctoral Associate | Metastatic Prostate Cancer Evolution @Nowak_Lab
Come and join our team in NYC @WeillCornell to work on #Metastatic #ProstateCancer #Evolution. Experience in #Genomics is a big advantage!
#ScienceJo...
https://jobrxiv.org/job/weill-cornell-medicine-27778-postdoctoral-associate-metastatic-prostate-cancer-evolution/?feed_id=43644
Client Info
Server: https://mastodon.social
Version: 2025.04
Repository: https://github.com/cyevgeniy/lmst