Pertussis toxin (Microbiology 🦠)
Pertussis toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. Research suggests PT may have a therapeutic role in treating a number of common human ailments, ...
https://en.wikipedia.org/wiki/Pertussis_toxin
#PertussisToxin #Ab5Toxins #Microbiology #WhoopingCough #ProteinFamilies #InvertebrateToxins
Lost & Found #6
by Christoph — In this episode, again three bookmarks that came to my attention while cleaning up our account on 𝕏 (formerly Twitter) and that are not at all out of date. Give them a brief look and judge for yourself. Here is Lost & Found #6.
Read more > https://schaechter.asmblog.org/schaechter/2025/05/lost-and-found-6.html
#microbiology
Life will find a way.
Often, the way involves working with others, but when conditions get hard, it's every microbe for themselves. It won't do to rely on a potentially less reliant ally.
https://www.eurekalert.org/news-releases/1082551
#sciencenews #microbiology
Whoa iqtree is finally up to version 3. It's setup in a separate github repo so if you rely on automated setup scripts (like I do) you'll have to make minor changes.
Time to run some tests to see if recent results remain consistent.
When you start working on bacterial immune systems and end up with RNA polymerase, sigma factors and quorum sensing:
The first part of the story is now online on BioRxiv!
https://www.biorxiv.org/content/10.1101/2024.09.12.612765v2
The regulation of the Type V-A CRISPR-Cas system in Francisella is modulated by a novel regulatory protein called MtvS. Intriguingly, MtvS-dependent regulation is mediated through quorum sensing despite the lack of canonical quorum sensing genes in Francisella.
#recommendations: looking for good RSS feeds that cater to #biology and/or #microbiology. General #science feeds are also appreciated if well written. Thanks in advance! #help #rss #rssfeed
ONT is finally fully discontinuing the original MinION Mk1B model (the original silver stick we're all familiar with). End of en era. I hope at least some future flow cells will continue to be compatible with the older platform 😔
Interested in #Cdiff #BugSlayers #sporulation and interdisciplinary research combining #microbiology #structuralbiology and #biochemistry? Please get in touch about possibilities to join us in #Salgadolab. #microSky
RE: https://bsky.app/profile/did:plc:oxo226vi7t2btjokm2buusoy/post/3lonofzfwk22l
Pseudouridine Stabilizes tRNA
Noteworthy — The modified nucleoside pseudouridine has many reasons to be considered a star among post-transcriptional RNA modifications. It was the first to be identified, in 1960. Incorporating it into mRNA vaccines was a big reason for their success. And it also shows up in numerous antibiotics. Now there's more.
Read more > https://schaechter.asmblog.org/schaechter/2025/05/pseudouridine-stabilizes-trna.html
#microbiology
https://open.spotify.com/show/35NfoxKLNe20JTXHXjOX3h?si=c55af01417ce4ba
“I’m thrilled to announce that the Garden State Microbiome podcast is now live on Spotify and Apple Podcasts!
This new weekly podcast showcases the marvelous microbiologists working in and around New Jersey, offering a look at the research, discoveries, and personal stories shaping our field.”
#microbiology
This bacteria is listed as a biowarfare agent and lurking in Australia's soil
By Tom Hartley
A deadly disease outbreak associated with the wet season in Northern Australia has created a medical mystery for Queensland scientists who are working tirelessly to understand its spread.
#InfectiousDiseases #Microbiology #MedicalResearch #ClimateChange #RespiratoryDiseases #HealthPolicy #Floods #TomHartley
🦠 How do dormant bacteria know when to wake up?
🔗 An ecological and stochastic perspective on persisters resuscitation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.002
📚 CSBJ: https://www.csbj.org/
#Microbiology #AntibioticResistance #SystemsBiology #InfectionRelapse #Persisters #StochasticProcesses #StochasticBiology #InfectionControl
'I was dying': After a heavy downpour, Luke spent 12 long days fighting for his life
By Tom Hartley and Kate Ainsworth
Luke Bantoft has survived melioidosis but the experience has left him "petrified" of returning to his home where he believes he caught it. Experts say the source of the outbreak could be the Bruce Highway upgrade.
#InfectiousDiseases #Microbiology #MedicalResearch #ClimateChange #RespiratoryDiseases #HealthPolicy #Floods #TomHartley #KateAinsworth
Joseph Lister, British surgeon and scientist, born OTD in 1827, performed the first truly antiseptic #surgery in 1865 https://toilet-guru.com/cholera-pump.html?s=mb #medicine #history #microbiology
"These mutation patterns are a kind of historical record in the genome, and they point to early-life exposure to colibactin as a driving force behind early-onset disease," said Dr Ludmil Alexandrov, a professor at University of California San Diego, among other appointments.
#cancer #research #science #medicine #bacteria #microbiology
Chrysamoeba es un alga ameboide de agua dulce con largos filopodios y un flagelo, usando pseudópodos para capturar su alimento.📷Ferry Siemensma #alga #algae #microbiologia #microbiology
Amazing find in Oregon: Cable bacteria that act like living wires. Named Candidatus Electrothrix yaqonensis, its unique structure could spark bioelectronic advances. #BioTech #Microbiology #Innovation
Evolution of Ant-Fungus Farming
by Mechas — Agriculture has triggered enormous changes in human society. But it is not unique to humans.
Read more > https://schaechter.asmblog.org/schaechter/2025/05/evolution-of-ant-fungus-farming-.html
#microbiology
Wishing y’all a wonderful #StarWarsDay and of course #InternationalRespectForChickensDay.
May the force, and the poultry, be with you.
🦠 Microbiologists discover new species of methane-producing archaea in the human gut
https://phys.org/news/2025-04-microbiologists-species-methane-archaea-human.html
#biology #microbiology #microbiome #archaea #bacteria #methane
