#myelination

2024-09-09

New #tissueclearing paper checks oligodendrocyte distribution throughout the entire mouse brain. Looks pretty neat!

Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan
Xu et al., preprint at biorxiv 2024
doi.org/10.1101/2024.09.06.611

Github: github.com/yxu233/Xu_Bergles_b

#neuroscience #lightsheet #microscopy #preprint #oligodendrocyte #myelination

Figure 1. Visualization of whole brain myelin patterns.
A. Oligodendrocyte somata and myelin sheaths are fluorescently labeled in Mobp-EGFP mice.
B. Representative confocal images showing colocalization of ASPA and endogenous EGFP.
C. Quantification of ASPA colocalization across mouse strain and age in gray and white matter.
D. Schematic illustration of clearing pipeline (left) along with images of cleared brains at each step
(right).
E. Schematic of brain mounting with UV light (purple) activated glue and 3D printed sample holders. Lightsheet illumination objectives scan perpendicular to sample.
F. Representative FOVs of single horizontal plane from lightsheet volume acquired with low
resolution 5×/0.16 NA air objective (left). FOVs highlight the diversity of myelin patterns across
brain regions (insets right).
2024-07-12

The diversity of #oligodendrocyte precursor cells (OPCs) is unclear. @Czopka_Lab explores a #PLOSBiology study describing a novel marker for a subpopulation of #OPCs that controls #oligodendrogenesis & #myelination. Paper: plos.io/3xS0sKE Primer: plos.io/3xTyrCx

2023-03-13

A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology plos.io/3YHNvdR

2023-03-13

A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology plos.io/3YHNvdR

2023-03-13

A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology plos.io/3YHNvdR

Javier Díaz-NidoJavier_DN@red.niboe.info
2023-02-06

Grammy Nominees Are a Brainy Bunch: Music Rewires the Brain

Our brains are hard-wired for the benefits of music. Every time a musician practices, their brains rewire by strengthening synapses, building new neurons, and rebuilding the myelin sheath.

#Neuroscience #Brain #Neuron #Synapse #SynapticPlasticity #Neurogenesis #Myelin #Myelination #Perception #Music

neurosciencenews.com/music-rew

2023-01-26

Anthea Weng, Erik Rabin & co show that alpha-T-catenin is expressed in peripheral #nerves as a constituent of Schwann cell adherens junctions:

journals.biologists.com/bio/ar

“We show that a cell connecting gene that is found in nerves and their surrounding supporting cells may play key roles in the basis of many diseases.”

We interviewed Anthea and Erik to find out more about their research:

journals.biologists.com/bio/ar

#Catenin #Myelination #Neuroglia #Neurons #Science #BiologyOpen #Biology

Anthea Weng and Erik Rabin.
Sara Hijazis_hijazi@mas.to
2022-11-21

#Introduction Hi! I am Sara and I’m still trying to get used to Mastodon.

I am a #neuroscientist and an #activist.

I am intrested in #inhibitory networks, learning and #memory , slice and in vivo #ephys and #myelination

I fight for #queerliberation and #transrights , against #racism and for a #freepalestine.

My favorite statement: The personal is political.

Christian Tidonatidona@mstdn.science
2022-11-18

Did you know that #myelination of neuronal axons by #oligodendrocytes in our #brain is a plastic process in which #myelin structure (white matter) can change in response to neuronal activity?

Here is a very interesting review article by Juliet Knowles and colleagues at Stanford University:

Adaptive and maladaptive myelination in health and disease

#OpenAccess article in Nature Reviews #Neurology: nature.com/articles/s41582-022

#neuroscience #psychiatricdiseases

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