#preclinical

Giuseppe MichieliGMIK69@mstdn.science
2025-02-14

#Antiviral Mechanisms and #Preclinical Evaluation of #Amantadine #Analogs that Continue to Inhibit #Influenza A Viruses with M2S31N-Based Drug Resistance, etidiohnew.blogspot.com/2025/0

2023-11-22

A company producing tissue samples in the lab, for drug discovery and preclinical research with robotics and artificial intelligence, raised $38 million in seed funding.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Biotechnology #Tissue #Organs #Preclinical #StartUp #University #Engineering #Finance #VentureCapital #SeedFunds #ArtificialIntelligence #Robotics

2023-11-08

There's one month left for early-bird registration for our 2024 Meeting '#Preclinical Modelling of Human Genetic Disease and #therapy' organised by Wendy Bickmore, Luke Boulter, Sara Brown, Pleasantine Mill, Editor-in-Chief Liz Patton and Editor Owen Sansom

Apply by 8 December at biologists.com/meetings/dmmgen
#dmmgenetics

Disease Models & Mechanisms meeting 'Pre-clinical Modelling of Human Genetic Disease and Therapy' is on 8 – 10 May 2024 at Institute of Genetics and Cancer, University of Edinburgh, UK. The early-bird registration deadline is 8 December 2023.
2023-10-18

The U.S. government's health preparedness agency awarded a contract with a university lab to explore organ models on chips to document effects of radiation sickness.

sciencebusiness.technewslit.co

#News #Press #Science #BARDA #Contract #Preclinical #OrganChip #Microfluidics #MedicalDevice #Radiation #ImmuneSystem #LymphNodes #Lung #Intestine #BoneMarrow

2023-10-05

Research with lab mice shows an experimental vaccine stimulates the body's basic immune system to protect against a range of pathogens associated with hospital infections.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Biotechnology #Chemistry #Infections #Hospital #Superbugs #Macrophage #Bacteria #Fungi #MRSA #Preclinical #Licensing #IntellectualProperty #University

2023-09-22

A start-up biotechnology company says it received the okay for its investigational new drug application of an anti-viral drug to treat a whole class of seasonal flu strains.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Biotechnology #Virus #InfluenzaA #FDA #SeasonalFlu #AntiViral #StartUp #Entrepreneurs #Preclinical #IND #ClinicalTrial #Regulations #Licensing

2023-09-13

A new award from National Institutes of Health funds preclinical work to prepare for a clinical trial assessing a treatment to reverse brain signaling damage in people with Alzheimer's disease.

sciencebusiness.technewslit.co

#News #Press #Science #Business #AlzheimersDisease #Neuroscience #Neuron #Synapse #Neurodegenerative #Preclinical #ClinicalTrial #ALS #RegenerativeMedicine #Australia #SBIR

2023-09-12

A new company developing treatments for neurological and psychiatric diseases from aberrant immune system activity is raising $58 million in seed funds.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Biotechnology #Finance #Autoimmune #Encephalitis #MentalHealth #Psychosis #SeedFunds #VentureCapital #Investment #Preclinical #FDA #OrphanDrug #RareDisease

2023-09-08

Researchers use stem cells to generate human neurons resembling those in the brain that control breathing during opioid reactions, for eventual chip devices to test overdose therapies.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Opioid #Overdose #Preclinical #Toxicity #Neurons #Breathing #Naloxone #Fentanyl #Codeine #Brain #Methadone #StemCells #Biotechnology #Engineering #Chemistry

2023-08-24

A health research foundation grant is funding development of a vaccine protecting against typhoid fever, given in a patch from from a spring-loaded device.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Collaboration #Foundation #Grant #Vaccine #TyphoidFever #Patch #MedicalDevice #Preclinical #ClinicalTrial

2023-08-18

A discoverer of neuroscience therapies and a genomics data science company are developing machine learning models to predict clinical trial outcomes for ADHD drugs.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Collaboration #Biotechnology #Algorithms #MachineLearning #Zebrafish #DrugDiscovery #ClincialTrials #Preclinical #ADHD #Neuroscience #Europe

2023-08-08

A women's health biotechnology company is partnering with a Brazilian drug maker to evaluate a precision target and treatment for ovarian health disorders.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Biotechnology #Collaboration #Melatonin #WomensHealth #Ovaries #PCOS #PrecisionMedicine #Infertility #Brazil #Preclinical #Licensing

2023-07-27

A group of academic and industry researchers exhibited in lab cells and mice a more direct delivery technique that could make gene therapies more accessible and inexpensive.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Biotechnology #Genetics #GeneTherapy #LipidNanoparticles #mRNA #SickleCell #StemCells #Preclinical #BoneMarrow

2023-07-25

A biotechnology company creating living tissue from a person's stem cells says it received FDA clearance for a clinical trial of its replacement knee cartilage.

sciencebusiness.technewslit.co

#News #Press #Science #Business #Tissue #Engineering #RegenerativeMedicine #StemCells #ClinicalTrial #Bone #Cartilage #Biotechnology #Preclinical #BoneMarrow #Adipose #University

2023-07-05

Biochip Device Tests Malaria Drug Efficacy, Safety

A lab-on-a-chip device with human organ cells is shown in lab tests to distinguish between malaria strains and detect drug toxicity when assessing blood for seven days.

sciencebusiness.technewslit.co

#News #Science #Business #Malaria #Parasite #Biochip #MedicalDevice #Preclinical #Engineering #Microfluidic #Blood #Toxicity #Liver #Spleen

Three-chamber malaria biochip device
Giuseppe MichieliGMIK69@mstdn.science
2023-06-07
2023-05-22

Safer Forms of Psilocybin Assessed in Preclinical Study

A #biotechnology company says it identified engineered precursors of a #psychedelic compound that in lab #animals produce safe and intended therapeutic effects.

sciencebusiness.technewslit.co

#News #Science #Business #Psilocybin #MagicMushrooms #Chemistry #Canada #MentalHealth #Psychoactive #Preclinical #Prodrug

Psilocybin mushrooms
2023-05-05

Crispr Therapy Shown to Remove E. Coli in Gut

New #research with lab #animals shows gene-edited viruses can target and remove harmful E. coli #bacteria from the #gut, including strains usually resistant to #antibiotics.

sciencebusiness.technewslit.co

#News #Science #Business #Biotechnology #Genomics #GeneEditing #Crispr #Ecoli #Preclinical #Microbiome #AntibioticResistance #GutMicrobes

Scanning electron microscope image of bacteriophages
2023-04-27

Low-Dose Covid-19 Vaccine Generates Strong Immune Response

Ultra-low quantities of an experimental Covid-19 #protein #vaccine delivered in synthetic cell components are shown in lab animals to generate strong #immune responses.

sciencebusiness.technewslit.co

#News #Science #Business #Biotechnology #Covid19 #SARSCoV2 #Preclinical #Exosomes #Nanoscale #ImmuneResponse #Antibody #TCells

Illustration of exosomes, extracellular vesicles from cells

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