#smFRET

2025-02-09

"Direct effect of membrane environment on the activation of mGluR2 revealed by single-molecule FRET" in #Structure

πŸ”— doi.org/10.1016/j.str.2025.01.

🧡 #GPCR #mGluR🧼#detergents #cholesterol
πŸ”¬ #smFRET
πŸ’»πŸ§ͺ #MD #mutants

Congrats to C. Banerjee, B. Liauw, and R. Vafabakhsh!

2024-12-21

Our preprint is up! Take a look if you like kinesin, microtubule transport, single molecule FRET or biophysics. It’s a bit of shift to how we’ve been used to thinking about kinesin-1 regulation as we try to get a handle on its conformational dynamics. Super proud of to have this milestone out in the world and all the hard work it represents from everyone involved.
#kinesin #microtubules #biophys #smFRET #SingleMolecule #AxonalTransport biologists.social/@Twelvetrees

Emmanuel Margeatemargeat@mstdn.science
2024-11-06

Check our new preprint !
Triple orthogonal labeling with 2 unnatural aminoacids + 1 SNAP-Tag for 3 color #smFRET.
We resolve a new intermediate in the activation of metabotropic glutamate receptor 2.

#GPCR #clickchemistry

biorxiv.org/content/10.1101/20

Collaboration with Jean Philippe Pin & Philippe Rondard (IGF Montpellier) & Don Lamb (LMU Munich)

2023-03-23

You are driving to St. Louis from England?? The boxes better have flotation devices πŸ˜‚πŸ˜‚
---
RT @EI_science
By delivering the EI-FLEX, we're not only providing them with a powerful tool πŸ› οΈ for #smFRET research, but we're also promoting the values of #OpenScience and #collaboration.

We can't wait to see the #innovative discoveries πŸ’‘ that will emerge from this partnership! twitter.com/Exciting_Ben/statu
twitter.com/EI_science/status/

Emmanuel Margeatemargeat@mstdn.science
2023-01-19

Only 2 weeks left to apply for the 3 postdoctoral positions available in our team, in the fields of atomic force microscopy #AFM, single molecule fluorescence spectroscopy (#smFRET) and #DNAorigami.
More info & application here
integrativebiophysicsofmembran

Emmanuel Margeatemargeat@mstdn.science
2022-11-28

Our team is hiring ! We are looking for three postdoctoral researchers in the field of atomic force microscopy #AFM, single molecule fluorescence spectroscopy (#smFRET) and #DNAorigami.
More info & application process here.
integrativebiophysicsofmembran

Please spread the info !

Emmanuel Margeatemargeat@mstdn.science
2022-11-22

Time for #introduction.
My name is Emmanuel Β« Manu Β» Margeat.
I develop and use single molecule fluorescence , including #smFRET, #FCS, and #SPT.
My research focuses on elucidating the structural dynamics and the interactions of #membrane #proteins, in vitro and in living cells.
I am strongly involved in research management, serving as deputy director of the #CBS, the Centre de Biologie Structurale in Montpellier , or as Council member for the french and the american Biophysical Society #BPS.

Hello #ScienceMastodon I am a biophysicist and leader of an active research group in the field of #singlemolecule studies, #smFRET #singlemoleculetracking and #superresolution microscopy at Ulm University. Looking forward to great scientific exchange

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