Online Now! Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00192-4?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells

Online Now! An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00191-2?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells

Prioritizing human tissue research: Q&A with Danilo Tagle https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00189-4?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Diversifying the reference iPSC line concept https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00184-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Hallmarks of MSCs: Key quality attributes for pharmacology and clinical use https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00188-2?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00177-8?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Vaccination-based immunotherapy to target profibrotic cells in liver and lung https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00182-1?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

3D reconstruction of a human Carnegie stage 9 embryo provides a snapshot of early body plan formation https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00142-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00141-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00144-4?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00099-2?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

An erythroid-biased FOShi hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00100-6?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00095-5?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00083-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Breathing new life into donor lungs: Theranostic methodology for organ repair https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00190-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

A new era in regenerative medicine: Cell replacement therapy for Parkinson’s disease is on the horizon https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00185-7?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

To play Paneth or goblet: Shapeshifting secretory cells read the room https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00186-9?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

On-demand microglia deliver the therapeutic payload in Alzheimer’s disease https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00183-3?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

From genes to geometry: Controlling embryo models by programming genomic activation https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00180-8?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Online Now! Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00187-0?rss=yes&utm_source=dlvr.it&utm_medium=mastodon #stemcells