Stephan Hacker

Assistant Professor at Leiden University. Covalent inhibitors and chemoproteomic technologies to discover new targets for antibiotics. Views my own. he/him/his
#Antibiotics #ChemicalBiology #Chemoproteomics #CovalentInhibitors #ChemiVerse #Chemistry #ChemBio

2026-02-12

Great opportunity to work as a #PhD or #postdoc with a great PI (Markus Lakemeyer), in the exciting scientific environment at Uni Jena.

Interested in #ChemBio, #Biochemistry, #Chemistry, #Microbiology and/or pharmaceutical sciences? Check it out:

PhD: jobs.uni-jena.de/jobposting/84
Postdoc: jobs.uni-jena.de/jobposting/c7

2026-02-12

We had a great #TuesdayTalk at our Faculty of Science this week by Sebastiaan Haffert. He talked about the various technological and scientific challenges of building extremely large telescopes that allow them to look for exoplanets and hopefully find proof for extraterrestrial life.

2026-02-03

RE: mstdn.science/@ChemBioTalks/11

I am very happy that we again managed to invite two world-leading scientists as keynotes for the 6th Virtual @ChemBioTalks.

We are working on an exciting additional program. Stay tuned!

Mailing list: fd24.formdesk.com/universiteit

#Chemistry #ChemBio #ChemBioTalks

2026-02-02

RE: mstdn.science/@LED3hub/1160023

Very much looking forward to the @LED3hub Lecture by Christina Woo! I am sure it will be a great one.

If you are interested in #ChemicalProteomics and/or targeted protein degradation #TPD, you will not want to miss it.

#Chemistry #ChemBio #DrugDiscovery #degrader

Stephan Hacker boosted:
2026-02-02

We are looking forward to the LED3 Lecture of Christina Woo on February 26th. She will talk about "Rewriting Protein Modifications".

If you are interested, make sure to come by!

universiteitleiden.nl/en/scien

#ChemBio #Chemistry #ChemicalProteomics #TPD

2026-01-29

Great @LED3hub Lecture by Anne Osbourn of the John Innes Centre. She talked about the amazing diversity of plant natural products, the gene clusters for their synthesis and their recombinant production for applications in #food and #health.

nature.com/articles/s41589-023

#Plants #NaturalProducts #Chemistry #ChemBio

Stephan Hacker boosted:
2026-01-29

We are very happy that Anne Osbourn from the John Innes Centre visited us today for a LED3 Lecture. She talked about "Harnessing plant metabolic diversity for food and health applications".

#Plants #NaturalProducts #GeneClusters #DrugDiscovery #ChemBio #Chemistry #Food #Health

Stephan Hacker boosted:
GDCh Division of BiochemistryGDCh_BioChem@mstdn.science
2026-01-26

Are you interested in cutting edge #Biochemistry and #ChemBio?

Check out our #Biochemistry2026 meeting in Würzburg from March 16th to 18th.

Deadlines for reduced early bird registration fee and abstracts have been extended to January 28th.

veranstaltungen.gdch.de/micros

2026-01-08

RE: mstdn.science/@LED3hub/1158590

We have an exciting remaining program for our @LED3hub Lectures of this academic year. Make sure to mark your calendars and come by.

Stephan Hacker boosted:
2026-01-08

Are you interested in cutting-edge research in Early Drug Discovery and Development?

We have an amazing program for our LED3 Lectures for the remaining months of this academic year. Make sure to check out the program and mark your calendars for the talks that you want to attend!

universiteitleiden.nl/en/scien

#DrugDiscovery #Chemistry #ChemBio #Seminars #Lectures

Stephan Hacker boosted:
2026-01-07

We are looking forward to the LED3 Lecture of Anne Osbourn on January 29th She will talk about "Harnessing plant metabolic diversity for food and health applications".

If you are interested, make sure to come by!

universiteitleiden.nl/en/scien

#ChemBio #Chemistry #Plants #Metabolites

Stephan Hacker boosted:
GDCh Division of BiochemistryGDCh_BioChem@mstdn.science
2026-01-07

If you are a #PhD candidate and want to attend #Biochemistry2026 (veranstaltungen.gdch.de/micros), make sure to apply for our meeting award, which comes with 500 € for the attendance and a free year of membership in @GDCh_BioChem!
en.gdch.de/network-structures/

Stephan Hacker boosted:
GDCh Division of BiochemistryGDCh_BioChem@mstdn.science
2026-01-07

Are you interested in cutting-edge #Biochemistry and #ChemBio? Join us for the GDCh #Biochemistry2026 conference in Würzburg on March 16th to 18th, 2026.

Registration is now open and you can submit an abstract until January 10th, 2026: veranstaltungen.gdch.de/micros
(1/2)

Stephan Hacker boosted:
GDCh Division of BiochemistryGDCh_BioChem@mstdn.science
2026-01-07

We have a great line-up of speakers including:
Jennifer Andexer, Helge Bode, Stephan Hammer, Akane Kawamura, Alexandria (Ali) Deliz Liang, Carina de Oliveira Mann, Stefan Raunser, Schraga Schwartz, Pierre Stallforth, Carine Tisné, Satpal Virdee, Wilfred van der Donk
#Chemistry #Meeting
CC: @gdch

Stephan Hacker boosted:
GDCh Division of BiochemistryGDCh_BioChem@mstdn.science
2026-01-07

📢 Deadline Extended to January 15th, 2026!

Apply for our Meeting Award to get:

✅ 500 € grant for the #Biochemistry2026 conference
✅ 1 year of free Fachgruppe Biochemie membership

Apply now: en.gdch.de/network-structures/

Share with a #ECR who needs to see this!

#Chemistry #ChemBio #PhD @gdch

2026-01-06

Great speech by the new president of Leiden University, Luc Sels, at the New Year's reception of our Faculty of Science. He gave great insights into his vision for the future of our university including excellent fundamental science, collaboration, internationalization and societal impact.

2026-01-06

Very interesting Tuesday Talk by Meindert Lamers at the New Year's reception of our Faculty of Science. He talked about the power of different electron microscopy techniques to visualize biological samples on length scales from tissues to individual molecules. nature.com/articles/s44386-025

2026-01-06

Our dean Jasper Knoester addresses our Science Faculty in his New Year's speech. Interesting insights into the future strategic goals of our faculty and great to hear him highlight the priority themes including the @LED3hub with new theme leader Mario van der Stelt.
universiteitleiden.nl/en/scien

2026-01-04

Overall, I hope that 2026 will yield at least the same degree of scientific progress as 2025. (12/12)

#Chemistry #ChemBio #Science #Antibiotics #Synthesis #TPD #Degrader #Proteomics #Kinases #RNA #Screening #CovalentInhibitors #DirectToBiology

2026-01-04

New antibiotic for Clostridioides difficile infections: The groups of Nathaniel Martin of our @LED3hub and of Wiep Klaas Smits of the LUMC published the powerful semisynthetic guanidino lipoglycopeptide EVG7 to treat Clostridioides difficile infections. While I saved #antibiotic discovery for last, there is surely still a high need for new antibiotics, may they be natural products, semisynthetic derivatives or fully synthetic compounds. (11/12)
nature.com/articles/s41467-025

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