The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research.
The mission of the GO Consortium is to develop a comprehensive, computational model of biological systems, ranging from the molecular to the organism level, across the multiplicity of species.
New GO data just out!! The July 2025 GO Release 2025-07-22 is now available.
➡️ http://current.geneontology.org
➡️ http://release.geneontology.org/2025-07-22
📓 DOI 10.5281/zenodo.16423886: https://doi.org/10.5281/zenodo.16423886
39,906 GO terms
9,417,935 annotations
1,602,275 gene products
5,497 species
More release notes at https://community.alliancegenome.org/t/july-2025-go-release-now-available/8468
Already bored of summer? Not to worry, a new GO Release is here!
https://current.geneontology.org/
https://release.geneontology.org/2025-06-01
10.5281/zenodo.15611813
40,122 GO terms
9,395,247 annotations
1,602,165 gene products
5,495 species
It's started!
If you're not in Geneva right now you're missing out on the 2025 Spring GOC Meeting!
https://community.alliancegenome.org/t/spring-2025-goc-meeting/8409
Last chance to register for the upcoming Spring GOC Meeting!
To all Consortium members, if you're planning on coming in-person to the meeting next month in Geneva, remember to register today! Check your email for the registration link, agenda, and hotel info.
You know about the PAN-GO Functionome, but have you explored the power of the Functional Category search? Learn how to find human genes of interest in just a few clicks, using the Functional Categories
Info on the @AllianceGenome forums: https://community.alliancegenome.org/t/8362
ICYMI, the original PAN-GO Functionome announcement: https://community.alliancegenome.org/t/8343
The PAN-GO #Functionome was announced last week in @Nature, but do you know how to use it?
Here's how to find functions for a selected human #gene:
➡️ https://community.alliancegenome.org/t/8353
ICYMI, more on the PAN-GO Functionome at the @AllianceGenome Forums:
💡 https://community.alliancegenome.org/t/8343
The PAN-GO #Functionome was announced last week in @Nature, but do you know how to use it?
Here's how to find functions for a selected human #gene:
➡️ https://community.alliancegenome.org/t/8353
ICYMI, more on the PAN-GO Functionome at the @AllianceGenome Forums:
💡 https://community.alliancegenome.org/t/8343
THE PAN-GO FUNCTIONOME IS LIVE! One of the most notable developments from the group that has been the leader in gene function knowledge for over 25 years. Read our brand new open access @Nature paper and explore the PAN-GO Functionome now!
🛠️ We ask the community to provide feedback to make sure the PAN-GO remains the most accurate resource- use the link on functionome.geneontology.org
Find links and more on the @AllianceGenome Forums: https://community.alliancegenome.org/t/8343
THE PAN-GO FUNCTIONOME IS LIVE! One of the most notable developments from the group that has been the leader in gene function knowledge for over 25 years. Read our brand new open access @Nature paper and explore the PAN-GO Functionome now!
🛠️ We ask the community to provide feedback to make sure the PAN-GO remains the most accurate resource- use the link on functionome.geneontology.org
Find links and more on the @AllianceGenome Forums: https://community.alliancegenome.org/t/8343
Is that love in the air? Yes! You'll LOVE this news- the February 2024 GO Release [2025-02-06](http://release.geneontology.org/2025-02-06/index.html) is now available!
[http://current.geneontology.org](http://current.geneontology.org/)
[http://release.geneontology.org/2025-02-06](http://release.geneontology.org/2025-02-06)
[10.5281/zenodo.14861039](https://doi.org/10.5281/zenodo.14861039)
❣️ 40,267 GO terms
💝 7,905,607 annotations
🧬 1,565,873 gene products
💖 5,443 species
For ontology changes in this release, see http://release.geneontology.org/2025-02-06/release_stats/go-ontology-changes.tsv
Annotation details are at http://release.geneontology.org/2025-02-06/release_stats/go-annotation-changes.tsv
The Spring 2025 GOC Meeting will be May 6-8 in Geneva! Will you be there? Registration details were sent out to all GOC members, check your email!
Wishing everyone a safe and happy holiday season! Although our downloads and other products should be available over the break, we will not have any staff available to address any enquiries until January 5th. We look forward to seeing you all when we return in January 2026!
It's time to start thinking about New Year's Resolutions. But what's one of the easiest ways to be healthier in the New Year? Why, by making sure your GO data is healthy!
Read more on the @alliancegenome.bsky.social forum: https://community.alliancegenome.org/t/go-start-the-new-year-right-with-healthy-data/7929
It's getting chilly; a familiar scent is in the air- but it's not pumpkin spice, it's the smell of a fresh new GO Release!
The November GO Release is out in the wild & ready to party!
current.geneontology.org
release.geneontology.org/2024-11-03
40,635 GO terms
8,031,345 annotations
1,568,326 gene products
5,435 species
Full details: https://community.alliancegenome.org/t/november-2024-release-now-available/7901
Did you know there are different ontology files, and the relations (and tool compatibility) varies between them? Read more on the @alliancegenome.bsky.social Forums:
https://community.alliancegenome.org/t/relations-the-ontology-file-you-use-matters/7887
GO traditionally focused on protein-coding genes, but a new publication by Antonazzo et al. highlights the recent expansion of ncRNA annotation. Definitely worth reading for both researchers and curators!
❓ GO puts the FUN in function, yes - but what is phenomenal for phenomics???
➡️ uPheno! Read more about the fantastic Unified Phenotype Ontology here:
https://community.alliancegenome.org/t/ever-needed-go-but-for-phenotypes-try-upheno/7831
Attention GO Consortium members: if you haven't yet registered or submitted topics of interest for the October GOC meeting, time is running out! Check your emails or the GO Wiki for links.
GOC Fall 2024 Meeting is Tuesday, Oct 15th- Thursday, Oct 17th & will be virtual.
The September 2024 GO Release (2024-09-08/) is now available!
http://current.geneontology.org/
http://release.geneontology.org/2024-09-08
10.5281/zenodo.13769908
40,939 GO terms
7,894,411 annotations
1,573,444 gene products
5,426 species
Ontology/annotation changes and release notes at https://github.com/geneontology/go-announcements/issues/851
The @AllianceGenome, of which GO is a founding member, will have a live webinar on September 19th: An Introduction to the Alliance". Register by Sep 18th!
https://community.alliancegenome.org/t/webinar-an-introduction-to-the-alliance/7798