Lmst

Gabrielle is giving a talk today in the Warwick SLS-WMS Postdoc Association Seminar Series.

"Hacking the logic of clathrin-coated vesicle creation”

10 am in A1.51, Gibbet Hill

Because #ScienceIsInternational, it means that #LabSnacksAreInternational. Some maple syrup treats from Quebec on the menu for today…
#LabLife

A packet of Maple cone blend (cornets à l’érable) from Quebec. The packet says 12 x 22g, but the seal is broken and you can see that at least two are missing.

James and Selena's paper is out in JCB!

We present a structural model of the interaction between TACC3 and ch-TOG. Then we discover Affimers that can inhibit this interaction. Expression of the Affimers in cells uncovered a new role for TACC3-ch-TOG in maintaining the pericentriolar material during mitosis.

https://doi.org/10.1083/jcb.202407002

#CellBiology #StructBio #cytoskeleton

Final day in the lab for Natalia. She brought in some Brazilian treats…

cheese balls and brigadeiros on a table - ready to eat!!

Paper accepted! 🎉 Details to follow…

Today's CMCB Lab Talk is from our lab and will be given by.... Steve 😮

"Structural characterisation and inhibition of the interaction between ch-TOG and TACC3”

A1.51 at 1pm

Royle Lab News boosted:

Paper accepted!! What a great way to start the day.

#LifeOfPI

And she's out! @MAFesenko passing with minor corrections 🎉 #PhDone

Photo of Mary with her examiners Sharon Tooze and John James

Mary is giving her pre-viva talk

#PhNearlyDone #CellBiology

Woman at a lectern delivering a talk with a screen behind her showing a cell and vesicles.

We made a lab fun page!

Come for pictures of scientists waiting for food in restaurants, stay for the bespoke album-inspired lab art!

https://roylelab.org/fun.html

Lab social: on Friday we went to Magic Wingdom and then on to an Escape Room. We made it out!

Four people in a room with a tiled floor. One person is sat on a ridiculously ornate medieval throne while two others stand at the side proud of the achievement of escaping the room, while another is kneeling to the side clutching a sword. None of them are in medieval dress which makes the picture look funny.

Today we had our LEAF certification inspection. LEAF is a standard set by UCL to improve the #sustainability and #efficiency of the #laboratory. A big thank you to Gabrielle Larocque, our lab green champion, who spearheaded our application. Posting now, because apparently it will take a while for our certification to come through!

We recently welcomed Anneline Moret to our lab. She will study for her PhD at Warwick and at CY Paris Cergy University.

Meet Anneline here:

https://roylelab.org/people/current/anneline_moret.html

Building our new website…
…time for another cuppa.

And now for some new News!

This week we welcomed Anneline Moret to our lab. Anneline is a EUTOPIA co-tutelle student between our lab and Paris Cergy University. She'll be working on engineered membrane traffic of integrin in a cancer context.

#CellBiology #MembraneTraffic

We said farewell to Laura Downie who moved to a postdoc position at KCL/Crick. Laura joined our lab in 2018 completing her PhD and a short postdoc with us.

Laura opening presents at her leaving party. She is sat on a red sofa in the atrium of our building with friends.

Also in October, Sahil defended his PhD in Paris.

Sahil was a EUTOPIA co-Tutelle student so-supervised by Steve and Ambroise Lambert & Olivier Gallet in CY Cergy Paris University.
Thesis title: “Advanced Tools for rapid targeted tuning of cell-microenvironment interactions in Ovarian cancer/Outils avancés pour la modulation du trafic des intégrines dans le cancer de l'ovaire”
Sahil starts a postdoc position at Kings in London very soon.

Wide angle picture of Sahil giving a talk at his defence. There is a title slide on the screen and Sahil is standing at a podium wearing a suit.

October was a busy month for the lab. Firstly, Jean Poylo finished his Masters project with us and moved to Grenoble to start his PhD. Good luck Jean!