#APOBEC3

Giuseppe MichieliGMIK69@mstdn.science
2024-05-03

Exploring #Viral #Genome #Profile in #Mpox #Patients during the 2022 #Outbreak, in a North-Eastern Centre of #Italy mdpi.com/1999-4915/16/5/726

7 novel #mutations were identified, including #SNVs located in genes that are involved in immune evasion mechanisms and/or viral #fitness, six of these appeared to be #APOBEC3-driven. Interestingly, three patients exhibited the coexistence of mutated and wild-type alleles for five non-synonymous variants.

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