REMAP-CAP Steroids Trial Results about to be discussed (not in covid)

#CCR24

HEMOTION Trial about to report results

HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN

#CCR24

PREOXI Trial results, I find interesting how different the practice seems to be around the world. Mapleson C is standard of care in my region, cheap, quick to setup with some ability to dial in PEEP. Also easy to ventilate in the event of difficulties intubating.
Personally I gave up using NIV except in exceptional circumstances due to the complexity & effects it had on distracting the team from the task at hand.
#CCR24

@DocEd well I think it’s fair to say this community led effort was quite idealistic and we haven’t recruited enough extroverts to get it going! But #CCR24 has reminded me how much great discussion we can have inside this community without needing the bigger audience that twitter offers

@DocEd interesting comment on twitter just now from you about misinterpreting frequentist CIs - could you give an example? I’m in the room at #ccr24 but I missed the transgression!

Putting #SPICE3 together with #A2Btrial it does now seem hard to justify the use of these drugs in the ICU. I’m not very compelled by the arguments that we should try again with even higher doses given the side effect profile of these agents. #CCR24

@Watergypsy Very interesting that the interaction with age that SPICE3 reported seemed to be completely absent in A2B. #CCR24

Another nicely designed & run trial that is unlikely to change my practice. Dexmed to help bridge extubation maybe a good future direction, using it early seems to require quite a lot of propofol!
#CCR24 #A2B

A2B Trial results about to report at #CCR24

PROPOFOL VS DEXMEDETOMIDINE VS CLONIDINE

Protection trial

Just published in NEJM

https://www.nejm.org/doi/full/10.1056/NEJMoa2403769

#CCR24

Excellent headline result! Significant reduction in AKI in the amino acid treated group.
5% absolute risk reduction.

Massive difference in the stage 3 subgroup!
#CCR24

PROTECTION Trial

INTRAVENOUS AMINO ACID THERAPY FOR KIDNEY PROTECTION IN CARDIAC SURGERY

Interesting previous experimental evidence, I’m keen to see the results…
#CCR24

BLING III results have been immediately rolled into an updated RCT meta-analysis, trend towards benefit with continuous infusions.
#CCR24

BLING III

https://jamanetwork.com/journals/jama/fullarticle/2819971

#CCR24

BLING III, amazing organisation and running of a huge trial. Results however unlikely to change my practice…
#CCR24

Opening the meeting with BLING III.
Usual stunning venue and string quartet!
#CCR24

Waiting to fly to the lovely Belfast for the Critical Care Reviews meeting.
#CCR24

Just 50 days to go before my favourite intensive care conference!

https://criticalcarereviews.com

#CCR24 #ICM #titanic