#FocalAdhesion

2025-01-22

⬆️ New #preprint ! ⬆️

#Cells seem to like to keep their proportions. All thru the process of spreading on a substrate, we find conserved ratios in size of #lamella (under which cell #FocalAdhesion patches grow) and cell body. We show that this requires the interplay of some global regulation (based on #mechanical interactions?) with local processes.

Reconstructed (r,z) cell body shapes and lamella growth as a function of time along spreading. The averaged spatial distribution of paxillin intensity along time is shown at the cell-substrate interface.

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