The EGFR #phosphatase RPTPγ is a #redox-regulated suppressor of promigratory signaling
Maitreyi Joshi, Philippe Bastiaens et al show that #RPTPγ is coupled to autocatalytic, ligandless #EGFR #phosphorylation by a ROS-mediated toggle-switch, enabling ultrasensitive EGFR activation at the plasma membrane
https://www.embopress.org/doi/10.15252/embj.2022111806
#RPTP%CE%B3
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