Wider use of #TranexamicAcid to reduce #SurgicalBleeding could benefit patients and health systems | The BMJ https://www.bmj.com/content/385/bmj-2024-079444 “Because there is strong evidence that tranexamic acid reduces bleeding and transfusion and no indication of any increased risk of thrombosis, the benefits exceed the harms in patients having major surgery. Even in patients who do not require #transfusion, reducing bleeding will reduce postoperative #anaemia and facilitate more rapid recovery.”

📚 Keeping Up with the Evidence 📚
The field of TXA in resuscitation is evolving rapidly. Ongoing research continues to refine our understanding of its optimal use, dosing strategies, and potential applications in various clinical contexts. Staying updated with the latest evidence is vital for healthcare professionals involved in resuscitation efforts.
#TranexamicAcid #Resuscitation #Hemostasis (7/7)

🌟 The Power of Timing: Early Administration 🌟
In the realm of TXA administration, timing is crucial. Research consistently highlights the importance of early initiation of TXA to maximize its benefits. The sooner it is administered after the onset of bleeding, the greater the potential for improved outcomes.
#TranexamicAcid #Resuscitation #Hemostasis (6/7)

🚑 Expanding the Application: Beyond Trauma 🚑
While TXA initially gained prominence in trauma resuscitation, its potential benefits are being explored in other critical care settings. From postpartum hemorrhage to gastrointestinal bleeding and even intracerebral hemorrhage, studies are investigating TXA's effectiveness in diverse scenarios.
#TranexamicAcid #Resuscitation #Hemostasis (5/7)

🔍 The CRASH-2 Trial: A Resounding Revelation 🔍
The landmark CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) trial paved the way for the use of TXA in resuscitation. This large-scale study involving over 20,000 trauma patients demonstrated that early administration of TXA significantly reduced mortality due to bleeding.
#TranexamicAcid #Resuscitation #Hemostasis (4/7)

🌪️ The Storm of Traumatic Hemorrhage 🌪️
Traumatic hemorrhage remains a leading cause of preventable death worldwide. In critical situations where severe bleeding jeopardizes a patient's life, prompt and effective hemostatic interventions are essential. This is where TXA steps in.
#TranexamicAcid #Resuscitation #Hemostasis (3/7)

💊 Understanding Tranexamic Acid 💊
TXA is an antifibrinolytic medication that works by preventing the breakdown of blood clots. It helps stabilize clot formation and reduces bleeding in various clinical scenarios. Originally used in surgical and trauma settings, TXA's potential benefits in resuscitation have sparked widespread interest and research.
#TranexamicAcid #Resuscitation #Hemostasis (2/7)

🩸 Tranexamic Acid 🩸
When it comes to resuscitation efforts, every tool that can potentially save a life is worth exploring. One such tool that has emerged as a game-changer is tranexamic acid (TXA). Today, let's delve into the use of TXA in resuscitation and its significant impact on patient outcomes.
#TranexamicAcid #Resuscitation #Hemostasis (1/7)

Referenced link: https://medicalxpress.com/news/2023-06-tranexamic-acid-trauma.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-06-tranexamic-acid-trauma.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1669021654549135360#m

RT by @physorg_com: Shining a new light on #tranexamicacid for trauma care @nejm https://www.nejm.org/doi/10.1056/NEJMoa2215457 https://medicalxpress.com/news/2023-06-tranexamic-acid-trauma.html

Did you know that #hypothermia can adversely affect blood clotting? This is why it is very important to keep acute #trauma patients warm.

We'll post links to informative content wherever we find it, and in this case that happens to be #linkedin

The First Clot Is The Best Clot by Safeguard Medical.

https://www.linkedin.com/pulse/first-clot-best-safeguard-medical/

#tranexamicacid #lacticacid #fibrinogen #ATC #acidaemia #mortality #medic #emergency

Any of you have #TranexamicAcid use #protocols you'd like to share? Primarily interested in who you do not give IV or PO to. Any experience with irrigation for #TotalJointReplacement?