#cgas

Mathrubhumi EnglishMathrubhumi_English
2025-11-22

Kerala-based private banks will soon launch the Capital Gains Accounts Scheme, enabling customers to claim tax exemption by depositing profits from property sales until a new home is bought or built. A major shift, as the facility was earlier limited to public sector banks. english.mathrubhumi.com/news/k

2023-12-11

#CoolPaper alert 📢📢
So pleased that this is out in published form
@PLOSBiology

The #evolutionary #origins of eukaryotic innate #immune systems have firmly crossed prokaryotic divide. Their study is fascinating, provides really interesting insights & avenues of future discovery

Ed Culbertson & Tera Levin reveal origins of 3 families of #antiviral proteins: CD-NTases (incl #cGAS), #STINGs & #Viperins; each connecting #animal & #bacterial immunity

plos.io/46SfBqM

Figure 5 of the article the post refers to, depicting the evolutionary origin of CD-NTases, Viperins and STINGs
2023-12-11

How did our #InnateImmune systems first evolve? Ed Culbertson & @tera_levin reveal origins of three families of #antiviral proteins: CD-NTases (incl #cGAS), STINGs & #Viperins; each reveals a different story connecting animal & bacterial immunity #PLOSBiology plos.io/46SfBqM

2023-04-17

Issue 8:
Review on RNA-mediated #heterochromatin formation in our RNA focus series

Highlight on common adaptive strategies to differently induced chromosomal instability #CIN

#cGAS/STING DNA sensing activating #immunoproteasomes

#Epigenetic reprogramming in plant shade responses

Cover: Yoo Lab, RIKEN

embopress.org/toc/14602075/202

This cover highlights the article Evidence for existence of an apoptosis-inducing BH3-only protein, sayonara, in Drosophila by Yuko Ikegawa, Sa Kan Yoo and colleagues. The study discovers the first cell death-inducing BH3-only protein in fruit flies, termed Sayonara. Sayonara, meaning 'Good bye' in Japanese, originally derives from a popular phrase used by samurai, the Japanese premodern warriors. (Cover concept by the authors; scientific illustration by SciStories)
2023-03-20

DNA sensing via the #cGAS/STING pathway regulates #immunoproteasome function and #MHC class I #antigen presentation to promote #Tcell activation - with implications for the pathology of idiopathic pulmonary fibrosis

Silke Meiners et al ForschungszentrumBorstel@norden.social

embopress.org/doi/10.15252/emb

Schematic visualization of the article's synopsis
2023-03-07

STING directly recruits #WIPI2 for #autophagosome formation during STING-induced #autophagy - autophagy-dependent clearance of cytoplasmic DNA attenuating #cGAS-STING signaling.

embopress.org/doi/10.15252/emb

Schematic visualization of the article's synopsis

Researchers report new mechanism in an ancient pathway of #immune response.

#cGAS #signaling

phys.org/news/2023-03-mechanis

2023-01-05

#DNAdamage #DNArepair #kinase #DNAPK and #cGAS synergize to induce cancer-related #inflammation in #glioblastoma
Clara Taffoni, Johanna Marines, Nadine Laguette et al at IGH Montpellier
embopress.org/doi/10.15252/emb

Schematic visualization of the article's synopsis
2022-12-22

R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response

nature.com/articles/s41586-022
#immuneresponse #immunesystem #dna #rna #rooms #cytoplasma #cgas

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