Spindle cell hemangioma:
👉 Young adults, distal extremities
👉 Dermal/SQ nodule(s)
🔬 Solid + vasoformative
🔬 ±Associated thrombosed BV
🔬 Spindle cells may have small vacuoles (lipoblast-like)
🧬 IDH1/2 mutations (germline = Maffucci syndrome)
#bstpath #dermpath #pathboards @pathology

Glomus Tumor:
💅 Tender, subungual nodule
🔬 Uniform small round cells
🔬 "Punched out" nuclei + distinct borders
🔬 Nested & perivascular arrangement
🔬 Rich vasculature (ranging from small to ectatic)
🔬 Hyalinized-to-myxoid stroma
🎨 SMA(+), Desmin(-)
#bstpath #dermpath #pathology #pathboards @pathology

A follow-up for Tuesday's case:

A brief review of Naevoid BCC (Gorlin) Syndrome 👇

🔬 WSI: https://kikoxp.com/posts/21314
💡 More Info: https://kikoxp.com/posts/21316

#dermpath #molpath #pathboards @pathology

27♀️ w/ multiple scalp lesions

➡️ What syndrome does this patient likely have?
➡️ Which gene/mutation is most common?
➡️ What are some other clinical manifestations?

🔬 WSI: https://kikoxp.com/posts/21314
💡 Answer: https://kikoxp.com/posts/21316

#dermpath #pathboards @pathology

Plexiform fibrohistiocytic tumor:
1️⃣ Kids/YAs, forearm
2️⃣ Nodules of histiocytoid cells + MNGCs
3️⃣ Infiltrative fascicles of spindle cells

Learn more:
➡️ https://buff.ly/3ielHhz ⬅️

#3thingstoknow #pathology #bstpath #dermpath #pedipath #pathboards #pathresidents #meded #pathmastodon #pathmast #pathstodon #pathodon @pathology

Papillary eccrine adenoma:
1️⃣ Rare; distal extremities; ♀️>♂️
2️⃣ Variably dilated ducts w/ papillae
3️⃣ Dense fibrous stroma

Learn more:
➡️ https://buff.ly/3F9OMnq ⬅️

#3thingstoknow #pathology #dermpath #pathboards #pathresidents #meded #pathtwitter #pathmastodon #pathmast #pathstodon #pathodon @pathology

Alveolar soft part sarcoma:
1️⃣ Kids/YAs; thigh; ♀️>♂️
2️⃣ Discohesive nests of large cells w/ pink, granular cytoplasm
3️⃣ t(X;17) - ASPL-TFE3

Learn more:
➡️ http://buff.ly/3idlJWV ⬅️

#3thingstoknow #pathology #bstpath #pathboards #pathresidents #meded #pathmastodon #pathmast #pathstodon #pathodon @pathology

My #bstpath wallhangers were a surprising hit, so I decided to make a more ✨polished✨ version

Please enjoy & let me know if you notice any errors!

Also available as a downloadable pdf:
➡️ bit.ly/3WNZIOp ⬅️

#pathology #pathtwitter #molpath #pathboards