#reviewedpreprint

2024-06-23

This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.”

‘Structural analysis of the dynamic ribosome-translocon complex’
elifesciences.org/reviewed-pre

Structure of TRAP and its contacts with the ribosome and Sec61.
2024-06-15

​​This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.”

‘Structural analysis of the dynamic ribosome-translocon complex’
elifesciences.org/reviewed-pre

Structure of TRAP and its contacts with the ribosome and Sec61.
2024-06-05

What’s it actually like to publish a #ReviewedPreprint with eLife?

We asked author Chunxiao Li, a palaeontologist at the University of Chinese Academy of Sciences. Read about her experience.
elifesciences.org/inside-elife

"Authors have significant autonomy over the papers. The entire publication and review processes are more transparent." From author Chunxiao Li
2024-05-25

Most species have two sexes. The protist Tetrahymena thermophila has seven.

This fundamental #ReviewedPreprint reveals how it recognises self and non-self mating-types with a novel protein complex. elifesciences.org/reviewed-pre

2024-05-12

Biomineralisation appears to have evolved multiple times using different materials. This #ReviewedPreprint reveals how ROCK, an actomyosin remodelling protein, controls the process in sea urchin larvae. elifesciences.org/reviewed-pre

fluorescence microscopy image of a sea urchin larva
2024-05-02

New #ReviewedPreprint presents a method to fluorescently label peptide MHC complexes on live dendritic cells, allowing for a better understanding of antigen-specific T cell interactions.

Public reviews by @eLife.

sciety.org/articles/activity/1

Labelling strategy presented in the study.
2024-04-24

Analysing T cell motion in different tissue environments: many parameters of T cell motion are similar across tissues, with the exception of parameters related to confinement.

#ReviewedPreprint with public reviews by @eLife.

sciety.org/articles/activity/1

2024-04-18

The origins of RNA viruses can be hard to trace. This #ReviewedPreprint considers a more recent origin for coronaviruses and suggests their diversification occurred mainly through host switching rather than diversification with hosts. elifesciences.org/reviewed-pre

A framework for testing scenarios of virus-host evolution, illustrated with the example of Coronaviridae and their mammalian hosts:
2024-04-17

The balance of mTOR complexes in Sertoli cells regulates the rate of sperm epigenetic ageing, new #ReviewedPreprint reports.

Public reviews by @eLife.

sciety.org/articles/activity/1

Schematic illustrating age-related changes in the balance of mTOR complexes in the apical compartment of seminiferous epithelium.
2024-04-10

What controls the repair of photosystem II, a key process in maintaining and optimising photosynthesis?

Tryptophan oxidation plays a critical role, new #ReviewedPreprint with public reviews by @eLife suggests.

sciety.org/articles/activity/1

2024-04-08

Reviewers of this #ReviewedPreprint on ageing and senescence changed their assessment of the evidence from “incomplete” to “compelling” following the latest revisions by authors. Take a look at the reviews and version histories here: elifesciences.org/reviewed-pre

illustration of a person, whose body is made of a tangle of DNA, holding the end of the strand in the form of a chromosome
2024-04-04

New #ReviewedPreprint improves gene models for the ferret genome and identifies neural progenitors that are comparable to those found in developing human brains.

Public reviews by @eLife.

sciety.org/articles/activity/1

2024-04-02

A new method to therapeutically harness myeloid cells which can be otherwise immunosuppressive and hamper T cell and immunotherapy responses – #ReviewedPreprint with public reviews by @eLife.

sciety.org/articles/activity/1

Confocal microscopy images of HEK293FT cells.
2024-03-27

New #ReviewedPreprint explores how transcription factors regulate transcription through cooperative binding to enhancers in Drosophila.

Check out the full preprint with public reviews by @eLife.

sciety.org/articles/activity/1

2024-03-25

New #ReviewedPreprint presents a tool to identify lysosome-associated proteins in C. elegans.

Read the full article and the public reviews by @eLife.

sciety.org/articles/activity/1

A quote from the preprint review written in grey on white background with orange triangles in two corners of the graphic. The quote reads: The authors "provide a compelling, in-depth assessment of how this method can be used to understand longevity pathways and identify novel proteins." eLife editors about Yu et al. (2023)
2024-03-23

Reviewers of this #ReviewedPreprint on ageing and #senescence changed their assessment of the evidence from “incomplete” to “compelling” following the latest revisions by authors. Take a look at the reviews and version histories here: elifesciences.org/reviewed-pre

illustration of a person, whose body is made of a tangle of DNA, holding the end of the strand in the form of a chromosome
2024-03-19

A cancer gene drives immune escape by stopping tumours and immune cells communicating using exosomes. #Cancer #ReviewedPreprint elifesciences.org/reviewed-pre

blue cancer cells under a microscope
2024-03-19

This #ReviewedPreprint investigates the predictive role of circulating tumor DNA in the prognosis of patients with metastatic triple-negative #BreastCancer.

Public reviews by @eLife.

sciety.org/articles/activity/1

Progression-free survival probability curve for patients with different ctDNA status.

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