"Runx co-factors compete to recruit a limited pool of Runx factors in early T-progenitors, and a modest increase in Runx protein availability at pre-commitment stages causes premature Runx occupancy at post-commitment binding sites. This results in striking T-lineage developmental acceleration by selectively activating T-identity and innate lymphoid cell programs."
#Immunology #Preprint #Runx #thymus
https://www.biorxiv.org/content/10.1101/2022.11.18.517146v1?med=mas
Funky! using XCP-ng (a #XenServer fork) to run containers using the #Docker or #Podman toolchain. It uses #runx to replace #runc from the default container platform make-up that backs the containers with #xen domains (VMs) instead of kernel namespaces and cgroups. I still need to check whether containers can be administered remotely via a Docker or Podman cli on a different computer, but this looks sweet as! https://xcp-ng.org/forum/topic/5085/runx-tech-preview