Overall, I hope that 2026 will yield at least the same degree of scientific progress as 2025. (12/12)

#Chemistry #ChemBio #Science #Antibiotics #Synthesis #TPD #Degrader #Proteomics #Kinases #RNA #Screening #CovalentInhibitors #DirectToBiology

Overall, I hope that 2026 will yield at least the same degree of scientific progress as 2025. (12/12) #Chemistry #ChemBio #Science #Antibiotics #Synthesis #TPD #Degrader #Proteomics #Kinases #RNA #Screening #CovalentInhibitors #DirectToBiology

Interesting paper by the group of Ashraf Brik in @jacs.acspublications.org. Pd-mediated modification of cyclic peptides allows to combinatorially generate S-arylated derivatives and directly screen them for activity in cells. pubs.acs.org/doi/10.... #ChemSky #ChemBio #DirectToBiology #D2B

Direct Cellular Screening of P...

Interesting paper by the group of Ashraf Brik in JACS. Pd-mediated modification of cyclic peptides allows to combinatorially generate S-arylated derivatives and directly screen them for activity in cells.

https://pubs.acs.org/doi/10.1021/jacs.5c09059
#ChemSky #ChemBio #DirectToBiology #D2B