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Unser Heft 10/2025 ist raus!

Titelthema: Letzte Folge des Wissenschaftsnarren

Außerdem:
- Großes Special #Hirnforschung
- #Homöpathie;
- Pflanzenabwehr;
- #Pille für den Mann;
- #RNA-Welt;
- Live-Cell-#Imaging;
- #Phagen-Therapie;
- …

Das ganze Heft online: https://www.laborjournal.de/rubric/aktuell/index.php

Titelblatt der neuen Laborjournal-Ausgabe 10/2025: Ein Narr sitzt auf einem Bahnsteig auf seinem Koffer und blättert mit traurigem gesichtsausdruck in einem Laborjournal-Heft. Im Bild Dachzeile und Überschrift "Der Wissenschaftsnarr geht – Ein Abschiedsgruß". Ganz unten in drei grünen Kästen nebeneinander Ankündigungen von drei weiteren Artikelthemen des abgebildeten Hefts.

🧬 When does molecular dynamics improve RNA models? Insights from CASP15 and practical guidelines. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.003

📚 CSBJ: https://www.csbj.org/

#RNA #StructuralBiology #CASP15 #ComputationalBiology #Bioinformatics #MolecularSimulation #MolecularDynamics #Biophysics #MolecularModeling

When does molecular dynamics improve RNA models? Insights from CASP15 and practical guidelines. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.003

🧟 How quickly mRNA degrades is linked to autoimmune disease risk

https://medicalxpress.com/news/2025-09-quickly-mrna-degrades-linked-autoimmune.html

#mrna #molbio #rna #autoimmune #disease #health #biology #medicine

We continue the 5th Virtual #ChemBioTalks with an exciting talk by Chengqi Yi, who talked about targeting and manipulating mutated #RNA to treat human diseases. Interesting insights into site-specific RNA modification. https://www.nature.com/articles/s41589-023-01531-y
#ChemBio #Chemistry #DrugDiscovery

🚀🎩 Welcome to the #pretentious #musings of a self-proclaimed non-expert, regurgitating #RNA #predictions as if it were rocket science. 🤯😴 Spoiler: It's 4.8k words of #mental #gymnastics that boils down to "I don't know, but here's a novel-length #think #piece anyway." 🧐📜
https://www.owlposting.com/p/rna-structure-prediction-is-hard #nonexpert #writing #HackerNews #ngated

#Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying #RNA to stay one step ahead. Now, researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a single protein, IGF2BP3, that links these two processes together in #leukemia cells.
#Biomedical #sflorg
https://www.sflorg.com/2025/09/bmed09262502.html

Rice black-streaked dwarf virus causes major yield loss in #cereal crops.
Xie et al. investigate the #molecular mechanisms of #infection by this devastating #disease.

https://doi.org/10.1111/jipb.13966

@wileyplantsci
#PlantScience #JIPB #rice #wheat #maize #phytopathology #virus #RNA #botany

A working model for RBSDV P6 suppressing rice antiviral RNA decay defense response.

Meet ClaPNAC - a Classifier of Protein–Nucleic Acid Contacts.

ClaPNAC identifies various types of nucleotide-aminoacid contacts in 3D structures of NA-protein complexes.
More in the preprint: https://doi.org/10.1101/2025.05.30.657037

#Bioinformatics #Protein #RNA #DNA #Structure #Contact #3D

RNA Book Of The Month

How Biology Shapes Philosophy, edited by David Livingstone Smith

How Biology Shapes Philosophy is a seminal contribution to the emerging field of biophilosophy. It brings together work by philosophers who draw on biology to address traditional and not so traditional philosophical questions and concerns.

#RNA #ReligiousNaturalism #Bookstodon

#Mitochondrial complex I (CI) assembly in plants is a complex, crucial process.
Chen et al. provide insights into CI assembly pathways in #maize 🌽and discuss the critical role of ZmGLDH and CRK1 in CI assembly.

https://doi.org/10.1111/jipb.13958

@wileyplantsci
#PlantScience #JIPB #RNA #botany