“This innovative strategy could potentially revolutionize our ability to address genetic hearing impairments, offering hope for more effective and durable treatments for individuals across a wider age range and at various stages of hearing loss progression.” #isogg #DNA #epigenetics #hearingloss #geneadons
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1511938/full
Job - Alert 💡
Doctoral Researcher in Functional Cancer Biology (m/f/d)
Deadline: 2025-07-26
Location: Germany, Frankfurt, Hessen
Apply: https://www.academiceurope.com/ads/doctoral-researcher-in-functional-cancer-biology-m-f-d/
#hiring #PhD #cancerbiology #cellbiology #cancerresearch #epigenetics #lifescience
Listos en #Gijón para empezar la 3ª Conferencia Severo Ochoa de la #SEBBM " #Epigenetics, #aging and #cancer "
https://sebbm.es/actividades-sebbm/3rd-severo-ochoa-conference-epigenetics-aging-and-cancer/
Experiments with cultured cells equivalent to human epidermis find that vitamin C promotes the proliferation of skin cells, specifically keratin-containing cells, leading to increases in skin thickness and strength. The mechanism is evidently demethylation of DNA, reactivating genes that control cell proliferation.
Summary: https://www.eurekalert.org/news-releases/1088729
Original paper: https://www.jidonline.org/article/S0022-202X(25)00416-6/fulltext
New to epigenetics? University College London has produced Epigenetics for the Lay Person. #DNA #isogg #epigenetics #geneadons
https://www.ucl.ac.uk/population-health-sciences/womens-health/research/epigenetics-lay-version
Researchers get viable mice by editing DNA from two sperm https://arstechni.ca/hpEB #reproduction #epigenetics #imprinting #Science #Biology
In the most recent episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified, the mechanisms governing epigenetic reprogramming, and the critical conditions that maintain genomic integrity during early development. #podcast #epigenetics #chromatin
Listen here: https://activemotif.com/podcasts-azim-surani
In this episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified, the mechanisms governing epigenetic reprogramming, and the critical conditions that maintain genomic integrity during early development. #podcast #epigenetics #chromatin
Listen here: https://activemotif.com/podcasts-azim-surani
"plant genomes exhibit hierarchical organization within the nucleus, into large A and B compartments, intermediate topologically associating domain (TAD)–like domains, and fine gene-scale chromatin domains."
"Examining the chromatin structures at different levels of the hierarchy allows us to elucidate their epigenetic features, providing insights into the three-dimensional organization of plant genomes."
https://academic.oup.com/jxb/advance-article/doi/10.1093/jxb/eraf218/8138202
“The authors explained that carnosic acid works by activating enzymes in the body's "natural defense system." They created a stable form known as diAcCA, which once consumed, converts to carnosic acid in the gut and is then absorbed into the bloodstream.”#isogg #dna #epigenetics #alzheimers #rosemary
https://www.foodandwine.com/rosemary-carnosic-acid-alzheimers-treatment-11754104
Korfmann et al. compare methylome and genome variation in two plant specoes, showing that CG methylation captures recent demographic events missed by SNPs, and present a new deep learning method using methylation to infer demographic histories.
🔗 doi.org/10.1093/gbe/evaf101
I often look for easy-to-understand excerpts in studies but this one was pretty complicated so I asked ChatGPT 4.5 to summarize:
“What did the researchers look at? They studied human cells that had mutations in three of the six proteins making up the Origin Recognition Complex (ORC)—a group typically known for starting DNA replication. It breaks the long-held view that ORC’s job ends at replication. #DNA #isogg #epigenetics
https://www.sciencedirect.com/science/article/pii/S221112472500587X
Inside Your Brain’s Thought Factory: The Science of Neural Creativity
#BrainScience #Neuroplasticity #Neurotransmitters #Epigenetics #MindAndConsciousness #NeuralSignals #Bioluminescence #BrainHealth #QuantumMind #CognitiveScience
“For example, APOE ε2 is known to offer protection against cardiovascular disease and Alzheimer’s. FOXO3A helps cells handle oxidative stress and repair DNA, both key processes in aging.” #DNA #epigenetics #isogg #aging #geneadons
https://scitechdaily.com/unlocking-the-secrets-of-longevity-how-centenarians-defy-aging/
New publication: Independent avian epigenetic clocks for ageing and development. #epigenetics #epigeneticclock #parusmajor #ageing #DNAmethylation
https://doi.org/10.1111/1755-0998.14128
“Why Aging Comes in Dramatic Waves in Our 40s and 60s
A new study suggests that waves of aging-related changes occur at two distinct points in our life” #DNA #isogg #aging #epigenetics
“In summary, this research presents a novel case for rilmenidine to be considered a potential calorie restriction mimetic through its prolongevity and health preserving effects, increased stress resistance, and increased autophagy.” #isogg #DNA #epigenetics
https://onlinelibrary.wiley.com/doi/10.1111/acel.13774
Discover how lifestyle choices like diet, exercise, and stress management shape epigenetics to boost health. Learn science-backed tips to influence gene expression and optimize wellness in our latest blog! #Epigenetics
http://learningbreeze.com/biology/how-lifestyle-choices-shape-epigenetics-and-boost-health/
In the most recent episode we talked with Petra Hajkova from the MRC Laboratory of Medical Sciences about her work on epigenetics research on mammalian development, highlighting DNA methylation, histone modifications, and TET enzymes, along with her journey in molecular genetics and future research on epigenetic maintenance. #podcast #epigenetics #chromatin
🎧 Listen here: https://activemotif.com/podcasts-petra-hajkova
Interesting study that may help combat super-bugs.
“Mutants deficient in these enzymes exhibit varying degrees of antifungal drug sensitivity.” #DNA #isogg #epigenetics #C.auris
