Sometimes a protein's name will skew towards a clinical application: it may not give a good indication of its tissue distribution. PAPPA:p & PAPPA2:p have no tryptic peptide overlap.

#PAPPA (pappalysin, pregnancy-associated plasma protein A) & #PAPPA2 (pappalysin 2, pregnancy-associated plasma protein A2): Human Protein Atlas mRNA tissue distributions & GPMDB protein tissue tabbulations. #proteomics