Interesting bioRxiv preprint by the group of Matt Disney. They used fully functionalized fragments to enrich their targets and identify their binding sites on #RNA. Interesting insights into preferential binding to UTRs and the construction of RiboTACs.

https://www.biorxiv.org/content/10.1101/2025.11.05.686775v1
#NucleicAcids #TargetedDegradation #Chemistry #ChemBio