Can AI detect acute myeloid leukemia at the same level as an expert? According to Carsten Marr and his team, the answer is yes. Read on to learn more about how the team of researchers trained AI to play a role in the hematopathology diagnostic process!
#hemepath
Here’s another view via core biopsy @NicoGagelmann@twitter.com #DailyHemepath #HemePath @HemOncFellows@twitter.com https://twitter.com/kmirza/status/1023403166354812931
Stain quality is crucial #hemepath #pathology #leusm
click here to learn more: https://kikoxp.com/posts/16027/public
#HairyCellLeukemia is a chronic condition often misunderstood even by professionals. We spoke with a patient expert and with the HCL Foundation’s Graeme Quest about how HCL diagnostics and treatment have transformed over the last 30 years.
https://thepathologist.com/subspecialties/the-leukemia-you-want-to-have
#hemepath #hematopathology #pathology #PathMastodon #cancer #leukemia
Have you seen our latest #hematology and #hematopathology content? Check out our roundup articles – and keep an eye out for more #hemepath coming soon!
If you're a fan of general hemepath, click here:
https://thepathologist.com/subspecialties/a-walk-on-the-hemato-path
If you're laser-focused on the molecular side of blood, click here:
https://thepathologist.com/subspecialties/zooming-in-on-hematopathology
#fASHion at #ASH22 (cc: @acweyand@twitter.com)
Reppin’ H&E and Giemsa colors in my tie today #PathAtash #hemepath
Normal bone marrow cells - what a joy to see!
Festive airport season is the best season!
Ready to represent #PathAtASH #hemepath at #ASH22
See y’all soon!
Pleased to have had the opportunity to publish on a groundbreaking benign #hematology clinic staffed by pathologists!
What do you think of this new approach? Will it change patient care - or how #pathology is viewed by other medical professionals (and by students)? Let us know!
https://thepathologist.com/subspecialties/a-space-waiting-to-be-filled
It's been a bit of a learning curve but I'm really enjoying my time on Mastodon so far. Looking forward to future interactions on this platform. Sharing my favorite image of a heart shaped monocyte. ❤️ #pathology #hemepath #pathart #pathmastodon
@MpncoD@twitter.com @doctorpemm@twitter.com @JoeKhouryMD@twitter.com @KuykendallMd@twitter.com @DJ_Royston@twitter.com @sanamloghavi@twitter.com .@JoeKhouryMD@twitter.com continues the session with a discussion of WHO classification in MPNs: an evolving paradigm @MpncoD@twitter.com #MPNSM #hemepath
cc: @doctorpemm@twitter.com @sanamloghavi@twitter.com @KuykendallMd@twitter.com @DJ_Royston@twitter.com
Will never get used to seeing/hearing me speak in a pre-recorded session | session 7 @MpncoD@twitter.com continues with me discussing 'what is the same, and what is new' in MF | The blood smear is invaluable! #hemepath
cc: @doctorpemm@twitter.com @JoeKhouryMD@twitter.com @KuykendallMd@twitter.com @DJ_Royston@twitter.com @sanamloghavi@twitter.com
Next up, #hemepath superstar @sanamloghavi@twitter.com discusses #MPNSM WHO classification – new updates from a hemapathologist’s perspective: what’s news/what’s changed
Session 7 @MpncoD@twitter.com
cc: @doctorpemm@twitter.com @JoeKhouryMD@twitter.com @KuykendallMd@twitter.com
@DJ_Royston@twitter.com
#hemepath
1) Pancreatic lipomatosis in Diamond‐Blackfan anemia: The importance of genetic testing in bone marrow failure disorders
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajh.25155?af=R
2) An analysis of BPDCN w/translocations involving MYC identifies t(6;8)(p21;q24) as a recurrent abnormality
https://onlinelibrary.wiley.com/doi/abs/10.1111/his.13668?af=R
3) Cryoglobulin-induced red blood cell morphologic changes
http://www.bloodjournal.org/content/131/26/2994
4) “Double-expressor” intravascular large B-cell lymphoma involving the female genital tract
http://www.bloodjournal.org/content/131/26/2993?sso-checked=true
#hemepath
1) A case of disseminated blastic plasmocytoid dendritic cell neoplasm
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajh.25109?af=R
2) Diagnosis of follicular lymphoma from the peripheral blood
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajh.25158?af=R
3) Did you ‘miss' me? A subtle case of intravascular large B‐cell lymphoma
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajh.25132?af=R
4) Exceptional microorganisms on blood smear
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajh.25145?af=R
5) TCR‐δ expression and γδ+ T‐cell infiltrates in primary cutaneous gamma‐delta T‐cell lymphoma and others
https://onlinelibrary.wiley.com/doi/abs/10.1111/his.13671?af=R
#hemepath
1) CSF3R mutations are frequently associated with abnormalities of RUNX1, CBFB, CEBPA, and NPM1 genes in AML
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.31586
2) Mixed-phenotype large granular lymphocytic leukemia (LGLL): a rare subtype in the LGLL spectrum
https://www.humanpathol.com/article/S0046-8177(18)30237-5/fulltext?rss=yes
3) EBV–associated nodal marginal zone lymphoma: part of the spectrum of posttransplant LPD?
http://journals.sagepub.com/doi/abs/10.1177/1066896918784184
4) Diagnostic algorithm for lower-risk myelodysplastic syndromes
https://www.nature.com/articles/s41375-018-0173-2
#hemepath
1) HHV8-associated lymphoproliferative disorder in the peripheral blood
http://www.bloodjournal.org/content/131/25/2868
2) CCR4 mutations associated with superior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment
http://www.bloodjournal.org/content/early/2018/06/20/blood-2018-02-835991?rss=1
3) Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations
http://www.bloodjournal.org/content/early/2018/06/21/blood-2018-04-843771.1
4) Diagnosis of NK and cytotoxic T-cell disorders: a review
https://www.diagnostichistopathology.co.uk/article/S1756-2317(18)30077-X/fulltext?rss=yes
#hemepath
1) Mutations in SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome
http://www.bloodjournal.org/content/early/2018/06/18/blood-2017-12-820308
2) A multiprotein supercomplex controlling oncogenic signalling in lymphoma
https://www.nature.com/articles/s41586-018-0290-0
3) “Faggot” neutrophils in acute promyelocytic leukaemia with ongoing tretinoin therapy
https://onlinelibrary.wiley.com/doi/abs/10.1111/bjh.15445?af=R
4) Visceral leishmaniasis presenting with pancytopenia and circulating blastlike lymphocytes
http://www.bloodjournal.org/content/131/25/2867
#hemepath
1) Gray platelet syndrome mimicking atypical autoimmune lymphoproliferative syndrome: the key is in the blood smear
http://www.bloodjournal.org/content/131/24/2737?sso-checked=true
2) The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
http://www.bloodjournal.org/content/131/24/2661
3) EBV‐positive nodal low‐grade B‐cell lymphoma w/BCL3, IgA and IRTA1 expression
https://onlinelibrary.wiley.com/doi/pdf/10.1111/pin.12687
#hemepath
1) Lymphomas w/pseudo-double hit BCL6-MYC due to t(3;8)(q27;q24) are assoc w/GC iimmunophenotype, extranodal involvement, and frequent BCL2 translocations
https://www.humanpathol.com/article/S0046-8177(18)30212-0/fulltext
2) Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice
http://www.bloodjournal.org/content/early/2018/06/12/blood-2017-08-802769
3) Interference of therapeutic monoclonal antibodies w/routine SPEP and immunofixation in patients with myeloma
https://academic.oup.com/ajcp/advance-article-abstract/doi/10.1093/ajcp/aqy037/5036791
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