I wrote a book: "The brain, in theory" (to be published by Princeton University Press).

First chapter and TOC:
http://romainbrette.fr/WordPress3/wp-content/uploads/2024/12/The-brain-in-theory-TOC-and-first-chapter.pdf

@allenmichie discovered Interplay in the past year or so and have adored it ever since

@neuralreckoning This is not my area of expertise, but I do think neurovascular coupling is considered activity-dependent (in a number of ways, including via glutamate transmission to astrocytes and small molecule/peptide secretion). Is that what you have in mind? https://pmc.ncbi.nlm.nih.gov/articles/PMC4821024/

Also perhaps of note, I do think the BOLD signal tends to be fairly well-aligned with FDG-PET signals measuring glucose-related metabolism, but I think it's a fairly recent development to be able to image them on similar spatiotemporal scales, so that may still be an active debate.
https://www.nature.com/articles/s41597-020-00699-5

there we go https://sciop.net/datasets/nih-reporter

From the lab of Helene Schmidt:

"Large-scale 3D EM connectomics dataset of mouse hippocampal area CA1", Corteze et al. 2025
https://www.biorxiv.org/content/10.1101/2025.04.04.647285v1.full

Spectacular.

#neuroscience #hippocampus #mouse

Excited to share a summary of my new preprint looking at exploration effects in ventral prefrontal and hippocampal fMRI networks. A 🧵 ...1.15

You want help understanding how science funding works so we can defend it? @analog_ashley has your back. Here is her entire lesson breakdown for how to teach about science funding, complete with slides, data, and a compassionate and student-centered approach.

https://www.thetransmitter.org/how-to-teach-this-paper/how-to-teach-students-about-science-funding/

@elduvelle one of my favorites as well!

Trainees (especially US): What could our community be doing better for you right now?

Maybe there’s an email you haven’t received? Or a meeting you wish were organized differently in the era of travel uncertainties?

Answering on behalf of a friend is great. If we don’t know, we can’t help.

@NicoleCRust In addition to Jonny's suggestion, which I second - just telling us what you do and don't know about what's going on would go a long way.

And, when you don't know what to say (which is every PI I've spoken to), try engaging with someone who has a better idea so you can update us.

For example, Seattle Children's Research Institute had our "associate VP of government relations and policy" give us an update at an all-hands, which was immensely helpful for contextualizing how state and federal elected officials and attorneys were responding to executive orders, and how we fit into that picture.

Did it give us immediate solutions? No. But it set some expectations, helped us think about timelines, and scoped the issues in tangible ways. Made it feel like someone could respond rationally; like the ship wasn't just sinking without a captain

A hippocampal population code for rapid generalization https://www.biorxiv.org/content/10.1101/2025.03.15.643456v1?med=mas

"In an interview with Lancaster Farming, [SUSS's Bob] Holmes discussed ambient country further, describing the genre as 'sustained instrumentation meant to evoke certain feelings.' Holmes believes ambient country is the meeting point between Pink Floyd’s psychedelia and the darker moments of The Velvet Underground."

What Is Ambient Country?:

https://countrytown.com/news/what-is-ambient-country/lKgqhomIi4o/19-02-24

Amazon is going to be disabling the privacy feature that processes voice commands locally on Echo devices at the end of this month. Instead, all voice commands will be sent to Amazon's cloud for processing.

I have already followed my own steps to remediate this:

1. Unplug Echo Device
2. Throw Echo Device in Trash
3. Done

#amazon #echo #privacy

Well, if you need something to do to keep your spirits up during these trying times, why not learn to draw with this 1913 book.

https://archive.org/details/whattodrawhowtod00lutz

Via https://publicdomainreview.org/collection/what-to-draw-and-how-to-draw-it-1913/

#art #drawing #books #WhatToDraw

In the past few months, I built my own DIY music streaming service so I could move away from Spotify and achieve more privacy, autonomy, and control over my music and music consumption, and better compensate artists for their work.

I just published a guide for others to do the same. It doesn't require coding or system administration (I don't know how to do either). Let me know what you think!

https://tech.raphmim.com/build-your-own-music-streaming-service-to-achieve-more-control-and-autonomy
#OpenSource #Privacy #Decentralization #Linux #Music #Streaming #Tech

Posted my favorite traditional #surfmusic records of 2024

https://www.stormsurgeofreverb.com/content/gremmy-awards-2024-best-trad-surf-record

The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. In her latest column, @Neurograce asks if this logic still serves us as we tackle more sophisticated outputs.

https://www.thetransmitter.org/systems-neuroscience/claims-of-necessity-and-sufficiency-are-not-well-suited-for-the-study-of-complex-systems/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20250207-grace-lindsay-study-of-complex-systems

"Dorothy Ashby was truly dedicated to music and culture. Her creations not only generated a deep appreciation for the harp in jazz, but her sound laid the foundation of so much music that we grew up on and listen to today."

Undaunted Perseverance — Harpist Brandee Younger on the legacy of Dorothy Ashby:

https://www.wbgo.org/music/2024-01-08/undaunted-perseverance-harpist-brandee-younger-on-the-legacy-of-dorothy-ashby

Over the past few weeks, science funding in the U.S. has become shrouded in uncertainty. Ten trainees with diversity-based funding share how the changes are affecting their research and career plans.

By @avaskham, Claudia López Lloreda, Calli McMurray

https://www.thetransmitter.org/funding/a-gut-punch-how-u-s-neuroscience-trainees-are-grappling-with-diversity-based-funding-flux/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20250214-trainees-grappling-with-diversity-funding-flux

If you are in the U.S., you can buy produce directly from black farmers and they will ship it to you. It can cost less than your supermarket and will piss off people in power.

https://blackfarmersindex.com/

#interesting #youshouldknow #food #economy #business #smallbusiness