Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness them are limited to a small fraction of bacteria. A team led by #HIRI has introduced an approach that can make more bacteria amenable to genetic engineering. The method, called IMPRINT, uses cell-free systems to enhance #DNA transformation across various bacterial strains. 🦠🧬 The findings were published in #MolecularCell: https://www.helmholtz-hiri.de/en/newsroom/news/detail/news/unlocking-the-world-of-bacteria/

Listen up, #CRISPR Fan(zor)atics! ✂️🧬 In a new #MolecularCell spotlight, Costas Patinios, a postdoc in #HIRI’s Beisel lab, recaps Feng Zhang's recent remarkable discovery describing eukaryotic #RNA-guided DNA endonucleases, called Fanzors. Read more here: https://authors.elsevier.com/a/1hjJC_OylrlCTl

hmmmm, the "exlusome"

#structbio #molecularcell #Science

From: @bioRxiv_cellbiol
https://botsin.space/@bioRxiv_cellbiol/109956833473897972

Beautiful work.
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RT @BeckmannLab
Check our most recent work in collaboration with the amazing @inada_lab. The study unveils the molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. #ribosome #cryoEM #MolecularCell Here's a thread with the most exciting findings🧵...
https://twitter.com/BeckmannLab/status/1626536169642110976

Reading about nonsense-mediated altered splicing. The original papers describing this phenomenon were published in #Science and #MolecularCell in 2002. Evidence that this phenomenon was probably not real was published in 2005 in #RNA.

This pattern is not exceptional. Who still remembers the claims published in #Science that #translation was nuclear ?